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Potassium in PDB 4mz1: Crystal Structure of the Inosine 5'-Monophosphate Dehydrogenase, with A Internal Deletion of Cbs Domain From Campylobacter Jejuni Complexed with Inhibitor Compound P12

Enzymatic activity of Crystal Structure of the Inosine 5'-Monophosphate Dehydrogenase, with A Internal Deletion of Cbs Domain From Campylobacter Jejuni Complexed with Inhibitor Compound P12

All present enzymatic activity of Crystal Structure of the Inosine 5'-Monophosphate Dehydrogenase, with A Internal Deletion of Cbs Domain From Campylobacter Jejuni Complexed with Inhibitor Compound P12:
1.1.1.205;

Protein crystallography data

The structure of Crystal Structure of the Inosine 5'-Monophosphate Dehydrogenase, with A Internal Deletion of Cbs Domain From Campylobacter Jejuni Complexed with Inhibitor Compound P12, PDB code: 4mz1 was solved by Y.Kim, M.Makowska-Grzyska, M.Gu, W.F.Anderson, A.Joachimiak, Csgid, Centerfor Structural Genomics Of Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 45.57 / 2.40
Space group I 4 2 2
Cell size a, b, c (Å), α, β, γ (°) 118.062, 118.062, 435.160, 90.00, 90.00, 90.00
R / Rfree (%) 17.2 / 21.2

Other elements in 4mz1:

The structure of Crystal Structure of the Inosine 5'-Monophosphate Dehydrogenase, with A Internal Deletion of Cbs Domain From Campylobacter Jejuni Complexed with Inhibitor Compound P12 also contains other interesting chemical elements:

Bromine (Br) 3 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the Crystal Structure of the Inosine 5'-Monophosphate Dehydrogenase, with A Internal Deletion of Cbs Domain From Campylobacter Jejuni Complexed with Inhibitor Compound P12 (pdb code 4mz1). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Crystal Structure of the Inosine 5'-Monophosphate Dehydrogenase, with A Internal Deletion of Cbs Domain From Campylobacter Jejuni Complexed with Inhibitor Compound P12, PDB code: 4mz1:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in 4mz1

Go back to Potassium Binding Sites List in 4mz1
Potassium binding site 1 out of 3 in the Crystal Structure of the Inosine 5'-Monophosphate Dehydrogenase, with A Internal Deletion of Cbs Domain From Campylobacter Jejuni Complexed with Inhibitor Compound P12


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of the Inosine 5'-Monophosphate Dehydrogenase, with A Internal Deletion of Cbs Domain From Campylobacter Jejuni Complexed with Inhibitor Compound P12 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K502

b:31.7
occ:1.00
O A:GLY298 2.7 27.2 1.0
O A:CYS301 2.8 31.7 1.0
O A:GLY296 3.1 30.0 1.0
O A:HOH604 3.5 24.7 1.0
C A:CYS301 3.7 30.2 1.0
C A:GLY298 3.8 30.8 1.0
C A:PRO297 4.0 26.8 1.0
O A:PRO297 4.0 27.1 1.0
CB A:CYS301 4.0 24.8 1.0
C A:GLY296 4.1 29.8 1.0
CA A:CYS301 4.2 26.2 1.0
N A:CYS301 4.2 26.8 1.0
N A:GLY298 4.2 27.9 1.0
CA A:PRO297 4.4 24.3 1.0
SG A:CYS301 4.6 33.0 1.0
CA A:GLY298 4.6 26.6 1.0
O A:SER299 4.7 32.3 1.0
N A:SER299 4.8 30.0 1.0
C A:SER299 4.8 28.5 1.0
N A:PRO297 4.8 26.2 1.0
N A:THR302 4.8 27.8 1.0
CA A:SER299 4.9 24.7 1.0

Potassium binding site 2 out of 3 in 4mz1

Go back to Potassium Binding Sites List in 4mz1
Potassium binding site 2 out of 3 in the Crystal Structure of the Inosine 5'-Monophosphate Dehydrogenase, with A Internal Deletion of Cbs Domain From Campylobacter Jejuni Complexed with Inhibitor Compound P12


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of the Inosine 5'-Monophosphate Dehydrogenase, with A Internal Deletion of Cbs Domain From Campylobacter Jejuni Complexed with Inhibitor Compound P12 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K502

b:27.3
occ:1.00
O B:GLY298 2.7 26.3 1.0
O B:CYS301 2.7 27.8 1.0
O B:GLY296 3.0 29.1 1.0
O B:HOH608 3.6 28.6 1.0
C B:CYS301 3.7 27.9 1.0
C B:GLY298 3.8 28.2 1.0
C B:PRO297 3.9 27.2 1.0
CB B:CYS301 3.9 25.7 1.0
O B:PRO297 4.0 30.3 1.0
N B:CYS301 4.1 27.0 1.0
CA B:CYS301 4.1 25.1 1.0
C B:GLY296 4.1 31.9 1.0
N B:GLY298 4.1 30.9 1.0
CA B:PRO297 4.3 26.6 1.0
O B:SER299 4.5 35.5 1.0
SG B:CYS301 4.5 36.1 1.0
CA B:GLY298 4.6 26.4 1.0
N B:SER299 4.7 27.8 1.0
C B:SER299 4.7 34.2 1.0
N B:PRO297 4.8 31.1 1.0
CA B:SER299 4.8 29.8 1.0
N B:THR302 4.8 25.7 1.0

Potassium binding site 3 out of 3 in 4mz1

Go back to Potassium Binding Sites List in 4mz1
Potassium binding site 3 out of 3 in the Crystal Structure of the Inosine 5'-Monophosphate Dehydrogenase, with A Internal Deletion of Cbs Domain From Campylobacter Jejuni Complexed with Inhibitor Compound P12


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of the Inosine 5'-Monophosphate Dehydrogenase, with A Internal Deletion of Cbs Domain From Campylobacter Jejuni Complexed with Inhibitor Compound P12 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K504

b:32.4
occ:1.00
O C:CYS301 2.8 26.8 1.0
O C:GLY298 2.8 32.8 1.0
O C:GLY296 3.0 32.5 1.0
O C:HOH650 3.7 29.3 1.0
C C:CYS301 3.7 25.1 1.0
C C:GLY298 3.9 30.5 1.0
CB C:CYS301 4.0 26.6 1.0
C C:PRO297 4.0 29.1 1.0
O C:PRO297 4.0 29.9 1.0
C C:GLY296 4.1 32.4 1.0
CA C:CYS301 4.2 25.6 1.0
N C:CYS301 4.2 31.7 1.0
N C:GLY298 4.3 28.6 1.0
CA C:PRO297 4.4 30.1 1.0
SG C:CYS301 4.6 34.4 1.0
O C:SER299 4.7 37.7 1.0
CA C:GLY298 4.7 24.6 1.0
N C:PRO297 4.8 29.4 1.0
C C:SER299 4.8 34.1 1.0
N C:THR302 4.8 25.2 1.0
N C:SER299 4.9 24.5 1.0

Reference:

Y.Kim, M.Makowska-Grzyska, M.Gu, W.F.Anderson, A.Joachimiak. Crystal Structure of the Inosine 5'-Monophosphate Dehydrogenase, with A Internal Deletion of Cbs Domain From Campylobacter Jejuni Complexed with Inhibitor Compound P12 To Be Published 2013.
Page generated: Mon Aug 12 11:36:14 2024

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