Potassium in PDB 4lcu: Structure of Kcsa with E118A Mutation

The structure of Structure of Kcsa with E118A Mutation, PDB code: 4lcu was solved by C.M.Nimigean, D.J.Posson, J.M.Mccoy, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.90 / 2.75
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	155.952, 155.952, 75.952, 90.00, 90.00, 90.00
R / Rfree (%)	18.3 / 21.6

The binding sites of Potassium atom in the Structure of Kcsa with E118A Mutation (pdb code 4lcu). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 6 binding sites of Potassium where determined in the Structure of Kcsa with E118A Mutation, PDB code: 4lcu:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6;

Potassium binding site 1 out of 6 in the Structure of Kcsa with E118A Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of Kcsa with E118A Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K201 b:37.2 occ:0.25 OG1 C:THR75 2.8 40.4 1.0 O C:THR75 3.0 45.6 1.0 K C:K202 3.3 39.0 0.2 CB C:THR75 3.4 42.1 1.0 C C:THR75 3.8 40.2 1.0 CA C:THR75 4.3 44.8 1.0 CG2 C:THR75 4.6 38.1 1.0 O C:THR74 4.8 40.2 1.0 N C:VAL76 4.8 25.1 1.0

Potassium binding site 2 out of 6 in the Structure of Kcsa with E118A Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of Kcsa with E118A Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K202 b:39.0 occ:0.25 O C:THR75 2.5 45.6 1.0 O C:VAL76 2.8 41.7 1.0 K C:K201 3.3 37.2 0.2 K C:K203 3.4 41.7 0.2 C C:VAL76 3.6 37.9 1.0 C C:THR75 3.7 40.2 1.0 CA C:VAL76 3.9 40.1 1.0 N C:VAL76 4.3 25.1 1.0 N C:GLY77 4.6 30.7 1.0 CA C:THR75 4.9 44.8 1.0 CB C:THR75 4.9 42.1 1.0 OG1 C:THR75 5.0 40.4 1.0

Potassium binding site 3 out of 6 in the Structure of Kcsa with E118A Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Structure of Kcsa with E118A Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K203 b:41.7 occ:0.25 O C:GLY77 2.3 46.8 1.0 O C:VAL76 2.7 41.7 1.0 C C:GLY77 3.3 37.6 1.0 K C:K202 3.4 39.0 0.2 K C:K204 3.6 40.9 0.2 C C:VAL76 3.8 37.9 1.0 CA C:GLY77 3.9 40.4 1.0 N C:TYR78 4.2 29.4 1.0 N C:GLY77 4.4 30.7 1.0 CA C:TYR78 4.6 39.5 1.0 O C:TYR78 4.8 35.5 1.0 C C:TYR78 4.9 42.8 1.0

Potassium binding site 4 out of 6 in the Structure of Kcsa with E118A Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Structure of Kcsa with E118A Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K204 b:40.9 occ:0.25 O C:TYR78 2.3 35.5 1.0 O C:GLY77 3.1 46.8 1.0 C C:TYR78 3.2 42.8 1.0 K C:K203 3.6 41.7 0.2 N C:GLY79 3.9 34.9 1.0 CA C:TYR78 3.9 39.5 1.0 C C:GLY77 4.1 37.6 1.0 CA C:GLY79 4.2 30.7 1.0 K C:K205 4.3 0.2 0.3 N C:TYR78 4.5 29.4 1.0

Potassium binding site 5 out of 6 in the Structure of Kcsa with E118A Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Structure of Kcsa with E118A Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K205 b:0.2 occ:0.25 O C:HOH302 3.8 72.8 1.0 O C:TYR78 4.2 35.5 1.0 K C:K204 4.3 40.9 0.2 CA C:GLY79 4.8 30.7 1.0 O C:GLY79 4.8 38.4 1.0

Potassium binding site 6 out of 6 in the Structure of Kcsa with E118A Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 6 of Structure of Kcsa with E118A Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K206 b:59.9 occ:0.25 O C:HOH305 3.3 40.3 1.0 O C:HOH306 3.4 69.7 1.0

D.J.Posson, A.N.Thompson, J.G.Mccoy, C.M.Nimigean. Molecular Interactions Involved in Proton-Dependent Gating in Kcsa Potassium Channels. J.Gen.Physiol. V. 142 613 2013.
ISSN: ISSN 0022-1295
PubMed: 24218397
DOI: 10.1085/JGP.201311057