Potassium in PDB 4km7: Human Folate Receptor Alpha (FOLR1) at Acidic pH, Triclinic Form

The structure of Human Folate Receptor Alpha (FOLR1) at Acidic pH, Triclinic Form, PDB code: 4km7 was solved by A.R.Kovach, A.S.Wibowo, C.E.Dann Iii, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.10 / 1.80
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	33.709, 55.384, 69.504, 72.23, 86.95, 90.12
R / Rfree (%)	22.2 / 26.9

The binding sites of Potassium atom in the Human Folate Receptor Alpha (FOLR1) at Acidic pH, Triclinic Form (pdb code 4km7). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Human Folate Receptor Alpha (FOLR1) at Acidic pH, Triclinic Form, PDB code: 4km7:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Human Folate Receptor Alpha (FOLR1) at Acidic pH, Triclinic Form


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human Folate Receptor Alpha (FOLR1) at Acidic pH, Triclinic Form within 5.0Å range: probe atom residue distance (Å) B Occ A:K301 b:14.9 occ:1.00 OG A:SER110 3.0 13.7 1.0 ND2 A:ASN220 3.1 27.0 1.0 NE1 A:TRP60 3.2 15.4 1.0 OD1 A:ASN112 3.3 16.5 1.0 ND2 A:ASN222 3.3 13.2 1.0 CB A:SER110 3.6 13.1 1.0 OD1 A:ASN220 3.7 25.9 1.0 CB A:ASN222 3.7 14.6 1.0 CG A:ASN220 3.8 26.0 1.0 CG A:ASN222 4.0 16.6 1.0 CE2 A:TRP60 4.0 16.2 1.0 CE2 A:PHE214 4.1 15.5 1.0 CG A:ASN112 4.1 12.4 1.0 CA A:SER110 4.1 13.0 1.0 CB A:ASN112 4.1 9.7 1.0 CD1 A:TRP60 4.2 10.2 1.0 CD A:PRO111 4.2 14.0 1.0 CZ2 A:TRP60 4.3 16.1 1.0 CD1 A:LEU106 4.3 18.7 1.0 CZ A:PHE214 4.6 17.1 1.0 N A:PRO111 4.8 14.3 1.0 N A:ASN112 4.8 11.7 1.0 C A:SER110 4.9 15.5 1.0

Potassium binding site 2 out of 2 in the Human Folate Receptor Alpha (FOLR1) at Acidic pH, Triclinic Form


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Human Folate Receptor Alpha (FOLR1) at Acidic pH, Triclinic Form within 5.0Å range: probe atom residue distance (Å) B Occ B:K301 b:14.8 occ:1.00 OG B:SER110 2.9 10.9 1.0 NE1 B:TRP60 3.2 14.4 1.0 ND2 B:ASN222 3.2 8.3 1.0 ND2 B:ASN220 3.3 13.4 1.0 OD1 B:ASN112 3.3 14.5 1.0 CB B:SER110 3.5 9.8 1.0 CB B:ASN222 3.7 9.3 1.0 OD1 B:ASN220 3.9 19.0 1.0 CG B:ASN222 4.0 11.3 1.0 CG B:ASN220 4.0 13.9 1.0 CE2 B:TRP60 4.1 14.0 1.0 CA B:SER110 4.1 11.9 1.0 CD1 B:TRP60 4.1 11.7 1.0 CB B:ASN112 4.1 11.2 1.0 CG B:ASN112 4.1 12.6 1.0 CD1 B:LEU106 4.2 19.0 1.0 CE2 B:PHE214 4.2 17.0 1.0 CD B:PRO111 4.3 10.1 1.0 CZ2 B:TRP60 4.4 13.8 1.0 N B:ASN112 4.7 9.8 1.0 N B:PRO111 4.8 12.1 1.0 CZ B:PHE214 4.8 18.2 1.0 C B:SER110 4.9 11.4 1.0 O B:HOH490 4.9 21.1 1.0

A.S.Wibowo, M.Singh, K.M.Reeder, J.J.Carter, A.R.Kovach, W.Meng, M.Ratnam, F.Zhang, C.E.Dann. Structures of Human Folate Receptors Reveal Biological Trafficking States and Diversity in Folate and Antifolate Recognition. Proc.Natl.Acad.Sci.Usa V. 110 15180 2013.
ISSN: ISSN 0027-8424
PubMed: 23934049
DOI: 10.1073/PNAS.1308827110