Potassium in PDB 4h33: Crystal Structure of A Voltage-Gated K+ Channel Pore Module in A Closed State in Lipid Membranes, Tetragonal Crystal Form

The structure of Crystal Structure of A Voltage-Gated K+ Channel Pore Module in A Closed State in Lipid Membranes, Tetragonal Crystal Form, PDB code: 4h33 was solved by J.S.Santos, G.A.Asmar-Rovira, G.W.Han, W.Liu, R.Syeda, V.Cherezov, K.A.Baker, R.C.Stevens, M.Montal, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	16.40 / 3.10
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	53.370, 53.370, 108.160, 90.00, 90.00, 90.00
R / Rfree (%)	28.1 / 30.5

The binding sites of Potassium atom in the Crystal Structure of A Voltage-Gated K+ Channel Pore Module in A Closed State in Lipid Membranes, Tetragonal Crystal Form (pdb code 4h33). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Crystal Structure of A Voltage-Gated K+ Channel Pore Module in A Closed State in Lipid Membranes, Tetragonal Crystal Form, PDB code: 4h33:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Crystal Structure of A Voltage-Gated K+ Channel Pore Module in A Closed State in Lipid Membranes, Tetragonal Crystal Form


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of A Voltage-Gated K+ Channel Pore Module in A Closed State in Lipid Membranes, Tetragonal Crystal Form within 5.0Å range: probe atom residue distance (Å) B Occ A:K201 b:0.9 occ:0.25 O A:GLY59 2.4 78.7 1.0 K A:K202 3.1 67.5 0.2 O A:VAL58 3.1 78.7 1.0 C A:GLY59 3.5 78.7 1.0 CA A:GLY59 4.2 74.3 1.0 C A:VAL58 4.2 78.9 1.0 N A:TYR60 4.5 75.7 1.0 N A:GLY59 4.7 75.0 1.0 CA A:TYR60 4.8 76.0 1.0

Potassium binding site 2 out of 3 in the Crystal Structure of A Voltage-Gated K+ Channel Pore Module in A Closed State in Lipid Membranes, Tetragonal Crystal Form


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of A Voltage-Gated K+ Channel Pore Module in A Closed State in Lipid Membranes, Tetragonal Crystal Form within 5.0Å range: probe atom residue distance (Å) B Occ A:K202 b:67.5 occ:0.25 O A:VAL58 2.6 78.7 1.0 K A:K201 3.1 0.9 0.3 C A:VAL58 3.5 78.9 1.0 O A:THR57 3.6 80.4 1.0 K A:K203 3.9 93.2 0.2 CA A:VAL58 4.1 75.9 1.0 C A:THR57 4.5 80.9 1.0 O A:GLY59 4.5 78.7 1.0 N A:GLY59 4.5 75.0 1.0 N A:VAL58 4.7 76.4 1.0 CA A:GLY59 4.9 74.3 1.0

Potassium binding site 3 out of 3 in the Crystal Structure of A Voltage-Gated K+ Channel Pore Module in A Closed State in Lipid Membranes, Tetragonal Crystal Form


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of A Voltage-Gated K+ Channel Pore Module in A Closed State in Lipid Membranes, Tetragonal Crystal Form within 5.0Å range: probe atom residue distance (Å) B Occ A:K203 b:93.2 occ:0.25 O A:THR57 2.9 80.4 1.0 K A:K202 3.9 67.5 0.2 OG1 A:THR57 3.9 93.7 1.0 C A:THR57 4.0 80.9 1.0 CB A:THR57 4.3 91.8 1.0 CA A:THR57 4.8 79.2 1.0

J.S.Santos, G.A.Asmar-Rovira, G.W.Han, W.Liu, R.Syeda, V.Cherezov, K.A.Baker, R.C.Stevens, M.Montal. Crystal Structure of A Voltage-Gated K+ Channel Pore Module in A Closed State in Lipid Membranes. J.Biol.Chem. V. 287 43063 2012.
ISSN: ISSN 0021-9258
PubMed: 23095758
DOI: 10.1074/JBC.M112.415091