Potassium in PDB 4g8n: Crystal Structure of the Kainate Receptor GLUK3 Ligand-Binding Domain in Complex with the Agonist G8M

The structure of Crystal Structure of the Kainate Receptor GLUK3 Ligand-Binding Domain in Complex with the Agonist G8M, PDB code: 4g8n was solved by R.Venskutonyte, J.S.Kastrup, K.Frydenvang, M.Gajhede, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.69 / 2.30
Space group	P 41 2 2
Cell size a, b, c (Å), α, β, γ (°)	67.821, 67.821, 122.881, 90.00, 90.00, 90.00
R / Rfree (%)	17 / 22.8

The structure of Crystal Structure of the Kainate Receptor GLUK3 Ligand-Binding Domain in Complex with the Agonist G8M also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Potassium atom in the Crystal Structure of the Kainate Receptor GLUK3 Ligand-Binding Domain in Complex with the Agonist G8M (pdb code 4g8n). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of the Kainate Receptor GLUK3 Ligand-Binding Domain in Complex with the Agonist G8M, PDB code: 4g8n:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Crystal Structure of the Kainate Receptor GLUK3 Ligand-Binding Domain in Complex with the Agonist G8M


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of the Kainate Receptor GLUK3 Ligand-Binding Domain in Complex with the Agonist G8M within 5.0Å range: probe atom residue distance (Å) B Occ A:K304 b:40.3 occ:1.00 O A:SER24 2.7 29.6 1.0 O A:HOH511 2.7 32.6 1.0 O A:HOH458 2.8 38.8 1.0 O A:ARG26 2.8 26.8 1.0 O A:HOH461 2.8 33.2 1.0 O A:HOH433 2.9 27.6 1.0 C A:SER24 3.7 33.2 1.0 C A:ARG26 3.8 28.2 1.0 O A:ASP25 4.3 58.6 1.0 CB A:SER24 4.3 26.4 1.0 C A:ASP25 4.4 40.0 1.0 CA A:SER24 4.4 32.1 1.0 N A:SER24 4.4 28.0 1.0 CA A:THR27 4.5 23.9 1.0 N A:THR27 4.6 23.9 1.0 N A:ARG26 4.6 31.1 1.0 N A:ASP25 4.6 33.8 1.0 CA A:ARG26 4.8 28.6 1.0 CA A:ASP25 4.8 41.3 1.0 OG A:SER24 4.9 35.2 1.0 N A:LEU28 4.9 25.2 1.0 CG A:LEU28 4.9 24.6 1.0

Potassium binding site 2 out of 2 in the Crystal Structure of the Kainate Receptor GLUK3 Ligand-Binding Domain in Complex with the Agonist G8M


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of the Kainate Receptor GLUK3 Ligand-Binding Domain in Complex with the Agonist G8M within 5.0Å range: probe atom residue distance (Å) B Occ A:K305 b:40.5 occ:0.50 O A:ASN5 2.8 51.0 1.0 OG A:SER52 2.9 18.2 1.0 O A:HOH402 3.0 15.9 1.0 CB A:SER52 3.8 16.6 1.0 C A:ASN5 3.9 55.9 1.0 N A:SER52 4.0 17.3 1.0 O A:ARG6 4.5 34.0 1.0 CA A:SER52 4.5 15.8 1.0 CA A:ASN5 4.6 66.1 1.0 C A:ARG6 4.6 36.5 1.0 C A:PHE51 4.7 18.9 1.0 OG A:SER7 4.8 30.2 1.0 N A:SER7 4.9 35.7 1.0 CA A:PHE51 4.9 15.3 1.0 CB A:ASN5 4.9 70.3 1.0 N A:ARG6 4.9 56.5 1.0

L.Juknaite, R.Venskutonyte, Z.Assaf, S.Faure, T.Gefflaut, D.J.Aitken, B.Nielsen, M.Gajhede, J.S.Kastrup, L.Bunch, K.Frydenvang, D.S.Pickering. Pharmacological and Structural Characterization of Conformationally Restricted (S)-Glutamate Analogues at Ionotropic Glutamate Receptors. J.Struct.Biol. V. 180 39 2012.
ISSN: ISSN 1047-8477
PubMed: 22789682
DOI: 10.1016/J.JSB.2012.07.001