Potassium in PDB 4dur: The X-Ray Crystal Structure of Full-Length Type II Human Plasminogen

All present enzymatic activity of The X-Ray Crystal Structure of Full-Length Type II Human Plasminogen:
3.4.21.7;

The structure of The X-Ray Crystal Structure of Full-Length Type II Human Plasminogen, PDB code: 4dur was solved by R.H.P.Law, T.Caradoc-Davies, J.C.Whisstock, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	125.25 / 2.45
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	144.620, 144.620, 233.670, 90.00, 90.00, 120.00
R / Rfree (%)	19 / 21.5

The structure of The X-Ray Crystal Structure of Full-Length Type II Human Plasminogen also contains other interesting chemical elements:

Chlorine

(Cl)

7 atoms

The binding sites of Potassium atom in the The X-Ray Crystal Structure of Full-Length Type II Human Plasminogen (pdb code 4dur). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the The X-Ray Crystal Structure of Full-Length Type II Human Plasminogen, PDB code: 4dur:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the The X-Ray Crystal Structure of Full-Length Type II Human Plasminogen


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of The X-Ray Crystal Structure of Full-Length Type II Human Plasminogen within 5.0Å range: probe atom residue distance (Å) B Occ A:K805 b:43.0 occ:1.00 O A:ASN294 2.8 20.6 1.0 O A:GLU221 2.9 18.8 1.0 O A:HOH1374 3.0 24.5 1.0 O A:HOH1063 3.0 32.8 1.0 O A:HOH1375 3.0 24.5 1.0 O A:ARG220 3.2 21.8 1.0 OG A:SER170 3.3 31.4 1.0 C A:GLU221 3.5 19.0 1.0 C A:ARG220 3.7 21.7 1.0 C A:ASN294 3.9 20.9 1.0 CB A:SER170 3.9 23.0 1.0 O A:HOH1591 4.1 46.0 1.0 N A:LEU222 4.1 14.8 1.0 CA A:LEU222 4.2 14.3 1.0 CA A:ASN294 4.2 16.0 1.0 N A:GLU221 4.2 16.7 1.0 O A:HOH1324 4.4 33.4 1.0 CA A:ARG220 4.4 19.2 1.0 CA A:GLU221 4.4 15.7 1.0 O A:LEU222 4.5 17.5 1.0 C A:LEU222 4.6 17.9 1.0 CB A:ASN294 4.7 15.1 1.0 CB A:ARG220 4.7 21.1 1.0 ND2 A:ASN217 4.9 11.6 1.0 O A:HOH1435 5.0 29.4 1.0

Potassium binding site 2 out of 2 in the The X-Ray Crystal Structure of Full-Length Type II Human Plasminogen


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of The X-Ray Crystal Structure of Full-Length Type II Human Plasminogen within 5.0Å range: probe atom residue distance (Å) B Occ B:K804 b:36.6 occ:1.00 O B:HOH1292 2.5 25.2 1.0 O B:ASN294 2.8 16.7 1.0 O B:GLU221 2.9 16.0 1.0 O B:HOH1214 3.0 33.8 1.0 O B:HOH1574 3.0 9.6 1.0 O B:ARG220 3.3 18.4 1.0 OG B:SER170 3.3 30.2 1.0 C B:GLU221 3.5 16.1 1.0 O B:HOH1406 3.6 43.6 1.0 C B:ASN294 3.8 17.7 1.0 C B:ARG220 3.8 18.3 1.0 N B:LEU222 3.9 12.0 1.0 CB B:SER170 3.9 21.6 1.0 CA B:LEU222 4.0 11.5 1.0 CA B:ASN294 4.1 13.2 1.0 N B:GLU221 4.3 13.4 1.0 O B:HOH1030 4.4 37.8 1.0 CA B:GLU221 4.4 12.7 1.0 O B:LEU222 4.5 15.4 1.0 C B:LEU222 4.5 15.2 1.0 O B:HOH1274 4.5 51.0 1.0 CA B:ARG220 4.6 15.5 1.0 CB B:ASN294 4.7 12.6 1.0 O B:HOH1514 4.8 48.3 1.0 OD1 B:ASN294 4.9 20.3 1.0 CB B:ARG220 4.9 16.9 1.0 O B:HOH1570 4.9 33.9 1.0 N B:PHE295 5.0 15.3 1.0

R.H.P.Law, T.Caradoc-Davies, N.Cowieson, A.J.Horvath, A.J.Quek, J.A.Encarnacao, D.Steer, A.Cowan, Q.Zhang, B.G.C.Lu, R.N.Pike, A.I.Smith, P.B.Coughlin, J.C.Whisstock. The X-Ray Crystal Structure of Full-Length Human Plasminogen Cell Rep V. 1 185 2012.
ISSN: ESSN 2211-1247
PubMed: 22832192
DOI: 10.1016/J.CELREP.2012.02.012