Potassium in PDB 4bew: Serca Bound to Phosphate Analogue

All present enzymatic activity of Serca Bound to Phosphate Analogue:
3.6.3.8;

The structure of Serca Bound to Phosphate Analogue, PDB code: 4bew was solved by N.D.Drachmann, D.Mattle, M.Laursen, M.Bublitz, C.Olesen, J.V.Moeller, P.Nissen, J.P.Morth, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.972 / 2.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	101.430, 108.870, 274.310, 90.00, 90.00, 90.00
R / Rfree (%)	16.87 / 20.74

The structure of Serca Bound to Phosphate Analogue also contains other interesting chemical elements:

Fluorine	(F)	6 atoms
Magnesium	(Mg)	4 atoms
Manganese	(Mn)	3 atoms

The binding sites of Potassium atom in the Serca Bound to Phosphate Analogue (pdb code 4bew). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Serca Bound to Phosphate Analogue, PDB code: 4bew:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Serca Bound to Phosphate Analogue


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Serca Bound to Phosphate Analogue within 5.0Å range: probe atom residue distance (Å) B Occ A:K1004 b:79.0 occ:1.00 O A:ALA714 2.7 53.6 1.0 O A:LYS712 2.8 47.2 1.0 O A:LEU711 2.9 48.9 1.0 OE1 A:GLU732 2.9 62.4 1.0 OE2 A:GLU732 3.0 64.0 1.0 O A:HOH2260 3.2 66.0 1.0 O A:HOH2265 3.3 74.3 1.0 CD A:GLU732 3.3 61.7 1.0 C A:LYS712 3.5 43.0 1.0 CA A:LYS712 3.7 49.8 1.0 O A:HOH2259 3.9 85.3 1.0 C A:ALA714 3.9 55.5 1.0 C A:LEU711 3.9 42.8 1.0 O A:GLU715 4.0 58.5 1.0 N A:GLY717 4.0 42.7 1.0 C A:GLU715 4.3 52.7 1.0 N A:LYS712 4.3 38.2 1.0 N A:ALA714 4.4 43.9 1.0 N A:LYS713 4.5 41.9 1.0 O A:ALA730 4.6 56.3 1.0 C A:ILE716 4.6 48.6 1.0 CA A:GLY717 4.6 39.9 1.0 CA A:ALA714 4.6 51.2 1.0 N A:ILE716 4.6 52.8 1.0 CA A:ILE716 4.7 51.1 1.0 C A:LYS713 4.7 44.8 1.0 CG A:GLU732 4.7 56.1 1.0 N A:GLU715 4.9 54.7 1.0 CA A:GLU715 4.9 51.2 1.0 CB A:LYS712 5.0 56.5 1.0

Potassium binding site 2 out of 2 in the Serca Bound to Phosphate Analogue


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Serca Bound to Phosphate Analogue within 5.0Å range: probe atom residue distance (Å) B Occ B:K1004 b:84.8 occ:1.00 O B:ALA714 2.7 54.6 1.0 O B:LYS712 2.8 58.0 1.0 OE2 B:GLU732 2.9 72.0 1.0 O B:LEU711 3.1 55.0 1.0 OE1 B:GLU732 3.4 73.7 1.0 C B:LYS712 3.5 50.0 1.0 CD B:GLU732 3.5 64.5 1.0 O B:HOH2086 3.6 76.3 1.0 CA B:LYS712 3.8 55.5 1.0 C B:ALA714 3.9 53.3 1.0 O B:GLU715 4.0 59.2 1.0 C B:LEU711 4.1 47.9 1.0 C B:GLU715 4.3 56.2 1.0 N B:GLY717 4.3 45.2 1.0 N B:ALA714 4.4 48.6 1.0 N B:LYS712 4.5 50.6 1.0 N B:LYS713 4.6 45.2 1.0 N B:ILE716 4.6 54.9 1.0 CA B:ILE716 4.7 49.3 1.0 CA B:ALA714 4.7 46.8 1.0 C B:LYS713 4.7 51.4 1.0 O B:ALA730 4.7 54.8 1.0 C B:ILE716 4.8 53.8 1.0 N B:GLU715 4.8 52.8 1.0 CA B:GLU715 4.8 52.3 1.0 CG B:GLU732 5.0 49.8 1.0

D.Mattle, N.D.Drachmann, X.Y.Liu, P.Gourdon, B.P.Pedersen, P.Morth, J.Wang, P.Nissen. Serca Bound to Phosphate Analogue To Be Published.