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Potassium in PDB 4av6: Crystal Structure of Thermotoga Maritima Sodium Pumping Membrane Integral Pyrophosphatase at 4 A in Complex with Phosphate and Magnesium

Enzymatic activity of Crystal Structure of Thermotoga Maritima Sodium Pumping Membrane Integral Pyrophosphatase at 4 A in Complex with Phosphate and Magnesium

All present enzymatic activity of Crystal Structure of Thermotoga Maritima Sodium Pumping Membrane Integral Pyrophosphatase at 4 A in Complex with Phosphate and Magnesium:
3.6.1.1;

Protein crystallography data

The structure of Crystal Structure of Thermotoga Maritima Sodium Pumping Membrane Integral Pyrophosphatase at 4 A in Complex with Phosphate and Magnesium, PDB code: 4av6 was solved by T.Kajander, J.Kellosalo, K.Kogan, K.Pokharel, A.Goldman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.832 / 4.00
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 85.800, 112.266, 109.714, 90.00, 103.00, 90.00
R / Rfree (%) 29.52 / 36.5

Other elements in 4av6:

The structure of Crystal Structure of Thermotoga Maritima Sodium Pumping Membrane Integral Pyrophosphatase at 4 A in Complex with Phosphate and Magnesium also contains other interesting chemical elements:

Magnesium (Mg) 8 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the Crystal Structure of Thermotoga Maritima Sodium Pumping Membrane Integral Pyrophosphatase at 4 A in Complex with Phosphate and Magnesium (pdb code 4av6). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of Thermotoga Maritima Sodium Pumping Membrane Integral Pyrophosphatase at 4 A in Complex with Phosphate and Magnesium, PDB code: 4av6:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in 4av6

Go back to Potassium Binding Sites List in 4av6
Potassium binding site 1 out of 2 in the Crystal Structure of Thermotoga Maritima Sodium Pumping Membrane Integral Pyrophosphatase at 4 A in Complex with Phosphate and Magnesium


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Thermotoga Maritima Sodium Pumping Membrane Integral Pyrophosphatase at 4 A in Complex with Phosphate and Magnesium within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K1733

b:0.8
occ:1.00
O4 A:PO41728 2.9 0.3 1.0
O A:ASN492 3.3 0.0 1.0
OD1 A:ASP696 3.6 0.2 1.0
CB A:ALA495 3.7 0.2 1.0
CE A:LYS695 3.7 0.8 1.0
NZ A:LYS499 3.8 0.3 1.0
CA A:ASN492 4.0 0.2 1.0
C A:ASN492 4.0 0.7 1.0
CD A:LYS695 4.1 0.8 1.0
OD2 A:ASP236 4.1 0.1 1.0
ND2 A:ASN492 4.3 0.5 1.0
N A:ALA496 4.3 0.1 1.0
P A:PO41728 4.3 0.1 1.0
CB A:ASN492 4.5 0.8 1.0
CG A:ASP696 4.5 0.0 1.0
C A:ALA495 4.5 0.7 1.0
OD2 A:ASP696 4.6 0.6 1.0
CA A:ALA495 4.7 0.5 1.0
O A:GLY491 4.7 0.8 1.0
CG A:LYS695 4.7 0.1 1.0
CB A:ALA496 4.8 0.6 1.0
CE A:LYS499 4.8 0.5 1.0
CA A:ALA496 4.8 0.5 1.0
O3 A:PO41728 4.8 0.8 1.0
O A:GLY656 4.8 0.2 1.0
NZ A:LYS695 4.8 0.6 1.0
CG A:ASN492 4.9 0.5 1.0
C A:GLY656 5.0 0.2 1.0
CB A:LYS695 5.0 0.1 1.0
CG A:ASP236 5.0 0.8 1.0
N A:GLY657 5.0 0.8 1.0

Potassium binding site 2 out of 2 in 4av6

Go back to Potassium Binding Sites List in 4av6
Potassium binding site 2 out of 2 in the Crystal Structure of Thermotoga Maritima Sodium Pumping Membrane Integral Pyrophosphatase at 4 A in Complex with Phosphate and Magnesium


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of Thermotoga Maritima Sodium Pumping Membrane Integral Pyrophosphatase at 4 A in Complex with Phosphate and Magnesium within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K1733

b:0.8
occ:1.00
O4 B:PO41728 3.0 0.1 1.0
O B:ASN492 3.3 0.5 1.0
OD1 B:ASP696 3.5 0.7 1.0
CB B:ALA495 3.6 0.7 1.0
CE B:LYS695 3.7 0.0 1.0
OD2 B:ASP236 3.9 0.6 1.0
NZ B:LYS499 3.9 0.8 1.0
CA B:ASN492 3.9 0.1 1.0
CD B:LYS695 4.0 0.7 1.0
C B:ASN492 4.0 0.0 1.0
ND2 B:ASN492 4.3 0.9 1.0
N B:ALA496 4.3 0.3 1.0
CG B:ASP696 4.4 0.3 1.0
C B:ALA495 4.4 0.8 1.0
P B:PO41728 4.4 0.2 1.0
OD2 B:ASP696 4.5 0.6 1.0
CB B:ASN492 4.5 0.7 1.0
CA B:ALA495 4.6 0.4 1.0
O B:GLY491 4.6 0.5 1.0
CE B:LYS499 4.6 0.6 1.0
CG B:LYS695 4.7 0.3 1.0
CG B:ASP236 4.7 0.0 1.0
CB B:ALA496 4.8 0.8 1.0
CA B:ALA496 4.8 0.1 1.0
O3 B:PO41728 4.9 0.4 1.0
CG B:ASN492 4.9 0.5 1.0
CD B:LYS499 4.9 0.9 1.0
CB B:LYS695 5.0 0.1 1.0
OD1 B:ASP236 5.0 0.9 1.0

Reference:

J.Kellosalo, T.Kajander, K.Kogan, K.Pokharel, A.Goldman. The Structure and Catalytic Cycle of A Sodium-Pumping Pyrophosphatase. Science V. 337 473 2012.
ISSN: ISSN 0036-8075
PubMed: 22837527
DOI: 10.1126/SCIENCE.1222505
Page generated: Mon Aug 12 10:04:19 2024

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