Potassium in PDB 4aqe: Crystal Structure of Deafness Associated Mutant Mouse Cadherin-23 EC1-2S70P and Protocadherin-15 EC1-2 Form I

The structure of Crystal Structure of Deafness Associated Mutant Mouse Cadherin-23 EC1-2S70P and Protocadherin-15 EC1-2 Form I, PDB code: 4aqe was solved by M.Sotomayor, W.Weihofen, R.Gaudet, D.P.Corey, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	22.69 / 2.27
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	174.023, 40.866, 84.775, 90.00, 102.95, 90.00
R / Rfree (%)	17.261 / 23.873

The structure of Crystal Structure of Deafness Associated Mutant Mouse Cadherin-23 EC1-2S70P and Protocadherin-15 EC1-2 Form I also contains other interesting chemical elements:

Calcium

(Ca)

7 atoms

The binding sites of Potassium atom in the Crystal Structure of Deafness Associated Mutant Mouse Cadherin-23 EC1-2S70P and Protocadherin-15 EC1-2 Form I (pdb code 4aqe). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Crystal Structure of Deafness Associated Mutant Mouse Cadherin-23 EC1-2S70P and Protocadherin-15 EC1-2 Form I, PDB code: 4aqe:

Potassium binding site 1 out of 1 in the Crystal Structure of Deafness Associated Mutant Mouse Cadherin-23 EC1-2S70P and Protocadherin-15 EC1-2 Form I


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Deafness Associated Mutant Mouse Cadherin-23 EC1-2S70P and Protocadherin-15 EC1-2 Form I within 5.0Å range: probe atom residue distance (Å) B Occ B:K1241 b:38.6 occ:1.00 O B:ASP157 2.8 21.2 1.0 O B:ASP159 2.8 23.3 1.0 O B:HOH2137 3.5 20.8 1.0 O B:GLY164 3.6 21.5 1.0 O B:HOH2134 3.9 25.9 1.0 C B:ASP157 4.0 21.8 1.0 C B:ASP159 4.0 23.5 1.0 CA B:GLY164 4.0 21.9 1.0 C B:GLY164 4.2 21.1 1.0 C B:ILE158 4.2 23.5 1.0 O B:ILE158 4.4 24.7 1.0 N B:ASP159 4.4 22.4 1.0 CA B:ILE158 4.4 22.7 1.0 N B:ILE158 4.7 22.5 1.0 CA B:ASP159 4.9 23.0 1.0 N B:ASP160 4.9 24.0 1.0 CA B:ASP160 4.9 25.4 1.0

M.Sotomayor, W.Weihofen, R.Gaudet, D.P.Corey. Structure of A Force-Conveying Cadherin Bond Essential For Inner-Ear Mechanotransduction Nature V. 492 128 2012.
ISSN: ISSN 0028-0836
PubMed: 23135401
DOI: 10.1038/NATURE11590