Atomistry » Potassium » PDB 3ukm-3vrs » 3um7
Atomistry »
  Potassium »
    PDB 3ukm-3vrs »
      3um7 »

Potassium in PDB 3um7: Crystal Structure of the Human Two Pore Domain K+ Ion Channel Traak (K2P4.1)

Protein crystallography data

The structure of Crystal Structure of the Human Two Pore Domain K+ Ion Channel Traak (K2P4.1), PDB code: 3um7 was solved by S.G.Brohawn, R.Mackinnon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 31.20 / 3.31
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 87.938, 130.852, 132.779, 90.00, 90.00, 90.00
R / Rfree (%) 31.7 / 32.3

Potassium Binding Sites:

The binding sites of Potassium atom in the Crystal Structure of the Human Two Pore Domain K+ Ion Channel Traak (K2P4.1) (pdb code 3um7). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 5 binding sites of Potassium where determined in the Crystal Structure of the Human Two Pore Domain K+ Ion Channel Traak (K2P4.1), PDB code: 3um7:
Jump to Potassium binding site number: 1; 2; 3; 4; 5;

Potassium binding site 1 out of 5 in 3um7

Go back to Potassium Binding Sites List in 3um7
Potassium binding site 1 out of 5 in the Crystal Structure of the Human Two Pore Domain K+ Ion Channel Traak (K2P4.1)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of the Human Two Pore Domain K+ Ion Channel Traak (K2P4.1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K310

b:0.2
occ:1.00
 O A:GLY133 4.3 0.8 1.0
CA A:ASN134 4.8 0.9 1.0
O B:GLY133 4.8 0.8 1.0

Potassium binding site 2 out of 5 in 3um7

Go back to Potassium Binding Sites List in 3um7
Potassium binding site 2 out of 5 in the Crystal Structure of the Human Two Pore Domain K+ Ion Channel Traak (K2P4.1)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of the Human Two Pore Domain K+ Ion Channel Traak (K2P4.1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K311

b:30.8
occ:1.00
 O A:TYR132 3.0 0.1 1.0
O A:PHE241 3.0 0.4 1.0
K A:K312 3.1 23.6 1.0
O A:GLY131 3.2 93.1 1.0
O A:GLY240 3.4 85.0 1.0
O B:PHE241 3.4 0.1 1.0
O B:GLY240 3.4 96.5 1.0
O B:TYR132 3.4 0.3 1.0
O B:GLY131 3.6 91.8 1.0
C A:PHE241 3.6 0.4 1.0
C A:TYR132 3.7 0.0 1.0
C B:TYR132 3.9 0.7 1.0
C B:PHE241 4.0 0.1 1.0
N A:GLY242 4.2 0.4 1.0
CA A:GLY242 4.2 0.5 1.0
CA A:TYR132 4.3 0.6 1.0
C A:GLY131 4.4 92.7 1.0
N A:GLY133 4.5 0.3 1.0
C A:GLY240 4.5 80.4 1.0
N B:GLY133 4.5 0.2 1.0
C B:GLY240 4.5 0.4 1.0
CA A:PHE241 4.5 94.8 1.0
N B:GLY242 4.6 0.0 1.0
CA B:TYR132 4.6 0.9 1.0
CA B:PHE241 4.6 0.5 1.0
CA B:GLY133 4.7 0.8 1.0
C B:GLY131 4.7 0.8 1.0
CA B:GLY242 4.7 0.6 1.0
CA A:GLY133 4.7 0.0 1.0
N A:TYR132 4.9 98.8 1.0

Potassium binding site 3 out of 5 in 3um7

Go back to Potassium Binding Sites List in 3um7
Potassium binding site 3 out of 5 in the Crystal Structure of the Human Two Pore Domain K+ Ion Channel Traak (K2P4.1)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of the Human Two Pore Domain K+ Ion Channel Traak (K2P4.1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K312

b:23.6
occ:1.00
 O A:ILE130 2.9 73.3 1.0
O A:GLY240 2.9 85.0 1.0
O A:VAL239 3.0 73.8 1.0
O A:GLY131 3.0 93.1 1.0
K A:K313 3.0 21.7 1.0
O B:GLY131 3.1 91.8 1.0
K A:K311 3.1 30.8 1.0
O B:ILE130 3.1 69.4 1.0
O B:GLY240 3.1 96.5 1.0
O B:VAL239 3.2 68.3 1.0
C A:GLY240 3.6 80.4 1.0
C B:GLY240 3.8 0.4 1.0
C A:GLY131 3.8 92.7 1.0
C B:GLY131 3.9 0.8 1.0
C A:ILE130 4.1 72.7 1.0
C A:VAL239 4.1 72.9 1.0
CA A:GLY240 4.1 73.2 1.0
C B:VAL239 4.2 75.5 1.0
CA B:GLY240 4.3 97.5 1.0
C B:ILE130 4.3 79.0 1.0
N A:PHE241 4.4 85.8 1.0
CA A:GLY131 4.5 85.3 1.0
CA B:GLY131 4.5 91.1 1.0
N A:GLY240 4.6 72.5 1.0
N B:GLY240 4.7 83.1 1.0
N B:TYR132 4.8 0.7 1.0
C A:PHE241 4.8 0.4 1.0
N B:PHE241 4.8 0.7 1.0
CA A:PHE241 4.8 94.8 1.0
N A:GLY131 4.8 76.4 1.0
N A:TYR132 4.8 98.8 1.0
O A:PHE241 4.8 0.4 1.0
N B:GLY131 4.9 85.7 1.0
CA A:TYR132 4.9 0.6 1.0
CA B:TYR132 5.0 0.9 1.0

Potassium binding site 4 out of 5 in 3um7

Go back to Potassium Binding Sites List in 3um7
Potassium binding site 4 out of 5 in the Crystal Structure of the Human Two Pore Domain K+ Ion Channel Traak (K2P4.1)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Crystal Structure of the Human Two Pore Domain K+ Ion Channel Traak (K2P4.1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K313

b:21.7
occ:1.00
 O A:VAL239 2.6 73.8 1.0
O A:ILE130 2.9 73.3 1.0
O B:VAL239 3.0 68.3 1.0
O B:THR129 3.0 64.4 1.0
K A:K312 3.0 23.6 1.0
O B:ILE130 3.0 69.4 1.0
O A:THR238 3.1 70.2 1.0
O B:THR238 3.1 68.0 1.0
O A:THR129 3.2 70.9 1.0
C A:VAL239 3.4 72.9 1.0
C A:ILE130 3.5 72.7 1.0
C B:ILE130 3.6 79.0 1.0
C B:VAL239 3.6 75.5 1.0
K A:K314 3.8 21.4 1.0
CA A:ILE130 3.8 71.1 1.0
CA A:VAL239 4.1 72.6 1.0
CA B:ILE130 4.1 79.4 1.0
C B:THR129 4.1 73.4 1.0
C A:THR238 4.1 70.1 1.0
C A:THR129 4.2 70.6 1.0
N A:GLY240 4.2 72.5 1.0
C B:THR238 4.2 78.9 1.0
CA B:VAL239 4.3 76.4 1.0
N B:GLY240 4.4 83.1 1.0
N A:ILE130 4.5 70.6 1.0
N B:ILE130 4.6 77.8 1.0
N A:VAL239 4.6 71.2 1.0
N B:GLY131 4.6 85.7 1.0
CA A:GLY240 4.6 73.2 1.0
N A:GLY131 4.6 76.4 1.0
N B:VAL239 4.7 77.6 1.0
CA B:GLY240 4.8 97.5 1.0
O A:GLY240 4.9 85.0 1.0
C A:GLY240 4.9 80.4 1.0
CA B:GLY131 5.0 91.1 1.0
CG2 A:ILE130 5.0 71.2 1.0
O B:GLY131 5.0 91.8 1.0

Potassium binding site 5 out of 5 in 3um7

Go back to Potassium Binding Sites List in 3um7
Potassium binding site 5 out of 5 in the Crystal Structure of the Human Two Pore Domain K+ Ion Channel Traak (K2P4.1)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Crystal Structure of the Human Two Pore Domain K+ Ion Channel Traak (K2P4.1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K314

b:21.4
occ:1.00
 OG1 B:THR129 3.1 68.0 1.0
O A:THR238 3.1 70.2 1.0
O B:THR129 3.2 64.4 1.0
OG1 A:THR238 3.2 68.1 1.0
OG1 B:THR238 3.3 69.0 1.0
O A:THR129 3.3 70.9 1.0
O B:THR238 3.4 68.0 1.0
OG1 A:THR129 3.4 68.4 1.0
CB B:THR129 3.6 74.5 1.0
CB A:THR238 3.8 68.3 1.0
K A:K313 3.8 21.7 1.0
CB A:THR129 3.9 69.6 1.0
C B:THR129 3.9 73.4 1.0
CB B:THR238 4.0 78.5 1.0
C A:THR238 4.0 70.1 1.0
C A:THR129 4.1 70.6 1.0
C B:THR238 4.2 78.9 1.0
CA B:THR129 4.5 74.6 1.0
CA A:THR238 4.6 69.2 1.0
CA A:THR129 4.7 70.5 1.0
N B:ILE130 4.7 77.8 1.0
O A:THR237 4.8 69.7 1.0
CG2 B:THR129 4.8 76.1 1.0
CA B:THR238 4.8 82.8 1.0
N A:ILE130 4.8 70.6 1.0
N A:VAL239 4.8 71.2 1.0
O B:THR128 4.9 71.7 1.0
CG2 A:THR238 4.9 67.7 1.0

Reference:

S.G.Brohawn, J.Del Marmol, R.Mackinnon. Crystal Structure of the Human K2P Traak, A Lipid- and Mechano-Sensitive K+ Ion Channel. Science V. 335 436 2012.
ISSN: ISSN 0036-8075
PubMed: 22282805
DOI: 10.1126/SCIENCE.1213808
Page generated: Sun Dec 13 23:23:51 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy