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Atomistry » Potassium » PDB 3rs9-3spj » 3sff | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Potassium » PDB 3rs9-3spj » 3sff » |
Potassium in PDB 3sff: Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived InhibitorEnzymatic activity of Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor
All present enzymatic activity of Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor:
3.5.1.98; Protein crystallography data
The structure of Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor, PDB code: 3sff
was solved by
T.Stams,
B.Vash,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3sff:
The structure of Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor also contains other interesting chemical elements:
Potassium Binding Sites:
The binding sites of Potassium atom in the Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor
(pdb code 3sff). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor, PDB code: 3sff: Jump to Potassium binding site number: 1; 2; Potassium binding site 1 out of 2 in 3sffGo back to Potassium Binding Sites List in 3sff
Potassium binding site 1 out
of 2 in the Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor
Mono view Stereo pair view
Potassium binding site 2 out of 2 in 3sffGo back to Potassium Binding Sites List in 3sff
Potassium binding site 2 out
of 2 in the Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor
Mono view Stereo pair view
Reference:
L.Whitehead,
M.R.Dobler,
B.Radetich,
Y.Zhu,
P.W.Atadja,
T.Claiborne,
J.E.Grob,
A.Mcriner,
M.R.Pancost,
A.Patnaik,
W.Shao,
M.Shultz,
R.Tichkule,
R.A.Tommasi,
B.Vash,
P.Wang,
T.Stams.
Human Hdac Isoform Selectivity Achieved Via Exploitation of the Acetate Release Channel with Structurally Unique Small Molecule Inhibitors. Bioorg.Med.Chem. V. 19 4626 2011.
Page generated: Sun Dec 13 23:23:11 2020
ISSN: ISSN 0968-0896 PubMed: 21723733 DOI: 10.1016/J.BMC.2011.06.030 |
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