Potassium in PDB 3s3x: Structure of Chicken Acid-Sensing Ion Channel 1 at 3.0 A Resolution in Complex with Psalmotoxin

The structure of Structure of Chicken Acid-Sensing Ion Channel 1 at 3.0 A Resolution in Complex with Psalmotoxin, PDB code: 3s3x was solved by R.J.P.Dawson, J.Benz, P.Stohler, T.Tetaz, C.Joseph, S.Huber, G.Schmid, D.Huegin, P.Pflimlin, G.Trube, M.G.Rudolph, M.Hennig, A.Ruf, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.92 / 2.99
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	232.396, 109.442, 127.269, 90.00, 119.81, 90.00
R / Rfree (%)	21.8 / 24.9

The structure of Structure of Chicken Acid-Sensing Ion Channel 1 at 3.0 A Resolution in Complex with Psalmotoxin also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Potassium atom in the Structure of Chicken Acid-Sensing Ion Channel 1 at 3.0 A Resolution in Complex with Psalmotoxin (pdb code 3s3x). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Structure of Chicken Acid-Sensing Ion Channel 1 at 3.0 A Resolution in Complex with Psalmotoxin, PDB code: 3s3x:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Structure of Chicken Acid-Sensing Ion Channel 1 at 3.0 A Resolution in Complex with Psalmotoxin


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of Chicken Acid-Sensing Ion Channel 1 at 3.0 A Resolution in Complex with Psalmotoxin within 5.0Å range: probe atom residue distance (Å) B Occ A:K1 b:1.0 occ:1.00 OE2 A:GLU417 3.8 1.0 1.0 OE2 B:GLU417 3.8 0.1 1.0 OE2 C:GLU417 3.9 0.5 1.0 CD A:GLU417 4.7 0.4 1.0 CD B:GLU417 4.7 0.1 1.0 OE1 A:GLU417 4.7 0.7 1.0 OE1 B:GLU417 4.8 0.3 1.0 CD C:GLU417 4.8 0.8 1.0 OE1 C:GLU417 4.8 0.2 1.0

Potassium binding site 2 out of 2 in the Structure of Chicken Acid-Sensing Ion Channel 1 at 3.0 A Resolution in Complex with Psalmotoxin


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of Chicken Acid-Sensing Ion Channel 1 at 3.0 A Resolution in Complex with Psalmotoxin within 5.0Å range: probe atom residue distance (Å) B Occ A:K2 b:97.0 occ:1.00 OD2 A:ASP260 3.2 77.5 1.0 OE1 A:GLU314 3.5 95.8 1.0 OE2 A:GLU314 3.6 0.5 1.0 OD1 A:ASP260 3.8 0.6 1.0 CG A:ASP260 3.8 0.3 1.0 CD A:GLU314 3.9 96.3 1.0 CD1 A:LEU258 4.1 77.1 1.0 NH1 A:ARG191 4.4 92.3 1.0 CG2 A:VAL353 4.4 49.6 1.0 CD2 A:LEU349 4.6 44.0 1.0 CG A:GLN261 4.7 39.0 1.0 CD1 A:LEU349 4.7 44.9 1.0 NE2 A:HIS328 4.8 88.0 1.0 CG A:LEU349 4.9 64.7 1.0

R.J.Dawson, J.Benz, P.Stohler, T.Tetaz, C.Joseph, S.Huber, G.Schmid, D.Hugin, P.Pflimlin, G.Trube, M.G.Rudolph, M.Hennig, A.Ruf. Structure of the Acid-Sensing Ion Channel 1 in Complex with the Gating Modifier Psalmotoxin 1. Nat Commun V. 3 936 2012.
ISSN: ESSN 2041-1723
PubMed: 22760635
DOI: 10.1038/NCOMMS1917