Potassium in PDB 3r65: Mthk Channel Pore E92Q Mutant

The structure of Mthk Channel Pore E92Q Mutant, PDB code: 3r65 was solved by N.Shi, W.Zeng, S.Ye, Y.Li, Y.Jiang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.43 / 1.80
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	63.560, 63.560, 43.973, 90.00, 90.00, 90.00
R / Rfree (%)	20.5 / 22.5

The binding sites of Potassium atom in the Mthk Channel Pore E92Q Mutant (pdb code 3r65). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Mthk Channel Pore E92Q Mutant, PDB code: 3r65:
Jump to Potassium binding site number: 1; 2; 3; 4;

Potassium binding site 1 out of 4 in the Mthk Channel Pore E92Q Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Mthk Channel Pore E92Q Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:K1 b:22.6 occ:0.25 O A:TYR62 2.8 16.4 1.0 O A:GLY61 3.1 16.2 1.0 K A:K2 3.2 28.4 0.2 C A:TYR62 3.5 17.1 1.0 CA A:TYR62 4.1 16.6 1.0 C A:GLY61 4.2 16.7 1.0 N A:GLY63 4.3 16.9 1.0 CA A:GLY63 4.6 17.5 1.0 N A:TYR62 4.7 16.0 1.0 O A:HOH8 4.8 37.6 1.0

Potassium binding site 2 out of 4 in the Mthk Channel Pore E92Q Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Mthk Channel Pore E92Q Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:K2 b:28.4 occ:0.25 O A:GLY61 2.8 16.2 1.0 K A:K3 3.0 19.4 0.2 O A:VAL60 3.0 16.1 1.0 K A:K1 3.2 22.6 0.2 C A:GLY61 3.7 16.7 1.0 C A:VAL60 4.1 16.8 1.0 CA A:GLY61 4.2 16.4 1.0 N A:TYR62 4.6 16.0 1.0 N A:GLY61 4.6 16.4 1.0 CA A:TYR62 4.8 16.6 1.0

Potassium binding site 3 out of 4 in the Mthk Channel Pore E92Q Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Mthk Channel Pore E92Q Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:K3 b:19.4 occ:0.25 O A:THR59 2.8 17.4 1.0 O A:VAL60 2.9 16.1 1.0 K A:K2 3.0 28.4 0.2 K A:K4 3.5 17.4 0.2 C A:VAL60 3.7 16.8 1.0 C A:THR59 4.0 16.6 1.0 CA A:VAL60 4.2 16.4 1.0 N A:VAL60 4.6 16.4 1.0 N A:GLY61 4.6 16.4 1.0 CA A:GLY61 5.0 16.4 1.0 O A:GLY61 5.0 16.2 1.0

Potassium binding site 4 out of 4 in the Mthk Channel Pore E92Q Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Mthk Channel Pore E92Q Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:K4 b:17.4 occ:0.25 OG1 A:THR59 2.8 17.5 1.0 O A:THR59 3.0 17.4 1.0 K A:K3 3.5 19.4 0.2 CB A:THR59 3.6 16.8 1.0 C A:THR59 3.9 16.6 1.0 CA A:THR59 4.4 16.6 1.0 CG2 A:THR59 4.8 17.0 1.0 N A:VAL60 4.9 16.4 1.0

N.Shi, W.Zeng, S.Ye, Y.Li, Y.Jiang. Crucial Points Within the Pore As Determinants of K+ Channel Conductance and Gating J.Mol.Biol. V. 411 27 2011.
ISSN: ISSN 0022-2836
PubMed: 21554888
DOI: 10.1016/J.JMB.2011.04.058