Atomistry » Potassium » PDB 3q9c-3rs8 » 3qxz
Atomistry »
  Potassium »
    PDB 3q9c-3rs8 »
      3qxz »

Potassium in PDB 3qxz: Crystal Structure of A Probable Enoyl-Coa Hydratase/Isomerase From Mycobacterium Abscessus

Enzymatic activity of Crystal Structure of A Probable Enoyl-Coa Hydratase/Isomerase From Mycobacterium Abscessus

All present enzymatic activity of Crystal Structure of A Probable Enoyl-Coa Hydratase/Isomerase From Mycobacterium Abscessus:
4.2.1.17; 5.3.3.8;

Protein crystallography data

The structure of Crystal Structure of A Probable Enoyl-Coa Hydratase/Isomerase From Mycobacterium Abscessus, PDB code: 3qxz was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 1.35
Space group P 32
Cell size a, b, c (Å), α, β, γ (°) 76.170, 76.170, 122.520, 90.00, 90.00, 120.00
R / Rfree (%) 15.1 / 16.9

Potassium Binding Sites:

The binding sites of Potassium atom in the Crystal Structure of A Probable Enoyl-Coa Hydratase/Isomerase From Mycobacterium Abscessus (pdb code 3qxz). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Crystal Structure of A Probable Enoyl-Coa Hydratase/Isomerase From Mycobacterium Abscessus, PDB code: 3qxz:
Jump to Potassium binding site number: 1; 2; 3; 4;

Potassium binding site 1 out of 4 in 3qxz

Go back to Potassium Binding Sites List in 3qxz
Potassium binding site 1 out of 4 in the Crystal Structure of A Probable Enoyl-Coa Hydratase/Isomerase From Mycobacterium Abscessus


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of A Probable Enoyl-Coa Hydratase/Isomerase From Mycobacterium Abscessus within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K262

b:12.7
occ:1.00
 O A:VAL48 2.7 13.5 1.0
O A:ASP45 2.7 16.9 1.0
O A:HOH275 2.7 23.0 1.0
O A:ASP43 2.8 12.3 1.0
O A:LEU42 2.8 13.0 1.0
OG1 A:THR95 2.9 10.8 1.0
C A:ASP43 3.4 13.2 1.0
C A:ASP45 3.7 18.8 1.0
CA A:ASP43 3.7 12.8 1.0
C A:VAL48 3.7 12.3 1.0
C A:LEU42 3.9 13.2 1.0
CB A:VAL48 4.0 14.2 1.0
C2 A:EDO266 4.0 19.4 1.0
N A:ASP45 4.1 16.9 1.0
CB A:THR95 4.1 9.9 1.0
CA A:VAL48 4.2 13.9 1.0
CG2 A:THR95 4.3 10.0 1.0
N A:ASP43 4.3 12.3 1.0
N A:VAL48 4.4 15.4 1.0
N A:ASP44 4.4 14.8 1.0
CA A:ASP45 4.4 17.8 1.0
CG1 A:VAL48 4.5 13.0 1.0
OD1 A:ASP43 4.5 12.2 1.0
O A:HOH352 4.6 23.6 1.0
N A:PRO46 4.6 19.3 1.0
C A:ASP44 4.6 16.9 1.0
O A:HOH535 4.7 29.0 1.0
CA A:PRO46 4.7 19.9 1.0
O2 A:EDO266 4.7 17.6 1.0
CB A:ASP45 4.9 18.1 1.0
C A:PRO46 4.9 19.5 1.0
N A:ARG49 4.9 11.2 1.0
C1 A:EDO266 5.0 23.3 1.0
CA A:ASP44 5.0 16.3 1.0

Potassium binding site 2 out of 4 in 3qxz

Go back to Potassium Binding Sites List in 3qxz
Potassium binding site 2 out of 4 in the Crystal Structure of A Probable Enoyl-Coa Hydratase/Isomerase From Mycobacterium Abscessus


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of A Probable Enoyl-Coa Hydratase/Isomerase From Mycobacterium Abscessus within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K263

b:19.7
occ:1.00
 O C:HOH563 2.8 23.2 1.0
O C:GLU172 2.8 11.8 1.0
O B:GLU172 2.8 12.3 1.0
O A:HOH559 2.8 24.6 1.0
O B:HOH553 2.8 18.7 1.0
O A:GLU172 2.9 13.1 1.0
C C:GLU172 4.0 9.5 1.0
C B:GLU172 4.0 9.8 1.0
C A:GLU172 4.1 11.1 1.0
O A:HOH560 4.2 19.9 1.0
O C:HOH408 4.3 18.8 1.0
O B:HOH561 4.3 38.8 1.0
O B:HOH552 4.3 15.6 1.0
CA C:THR173 4.4 8.2 1.0
CA B:THR173 4.5 9.0 1.0
CA A:THR173 4.5 9.0 1.0
O A:HOH368 4.5 13.1 1.0
O B:HOH558 4.5 15.4 1.0
O C:HOH554 4.5 14.6 1.0
C B:THR173 4.6 7.6 1.0
C C:THR173 4.6 7.7 1.0
C A:THR173 4.6 8.2 1.0
O B:HOH555 4.6 8.7 1.0
O A:HOH557 4.6 13.7 1.0
O B:THR173 4.6 9.0 1.0
O C:HOH556 4.7 9.2 1.0
N C:THR173 4.7 8.1 1.0
O A:THR173 4.7 9.3 1.0
O C:THR173 4.7 8.4 1.0
N B:THR173 4.7 8.7 1.0
N A:THR173 4.8 9.5 1.0

Potassium binding site 3 out of 4 in 3qxz

Go back to Potassium Binding Sites List in 3qxz
Potassium binding site 3 out of 4 in the Crystal Structure of A Probable Enoyl-Coa Hydratase/Isomerase From Mycobacterium Abscessus


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of A Probable Enoyl-Coa Hydratase/Isomerase From Mycobacterium Abscessus within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K262

b:11.3
occ:1.00
 O B:VAL48 2.7 11.2 1.0
O B:ASP45 2.7 14.7 1.0
O B:HOH589 2.7 16.0 1.0
O B:ASP43 2.8 11.3 1.0
O B:LEU42 2.8 10.6 1.0
OG1 B:THR95 2.9 9.7 1.0
C B:ASP43 3.4 11.0 1.0
C B:ASP45 3.7 15.7 1.0
CA B:ASP43 3.7 9.9 1.0
C B:VAL48 3.8 11.2 1.0
C B:LEU42 3.9 9.3 1.0
C1 B:EDO266 3.9 18.7 1.0
CB B:VAL48 4.0 11.6 1.0
N B:ASP45 4.1 14.0 1.0
CB B:THR95 4.1 8.2 1.0
CA B:VAL48 4.3 12.2 1.0
N B:ASP43 4.3 10.0 1.0
CG2 B:THR95 4.3 9.2 1.0
N B:VAL48 4.4 13.7 1.0
N B:ASP44 4.4 11.7 1.0
OD1 B:ASP43 4.4 10.6 1.0
CA B:ASP45 4.5 15.2 1.0
CG1 B:VAL48 4.5 11.8 1.0
O B:HOH590 4.5 32.8 1.0
O B:HOH591 4.5 17.6 1.0
N B:PRO46 4.6 16.5 1.0
C B:ASP44 4.7 14.7 1.0
CA B:PRO46 4.7 17.1 1.0
O1 B:EDO266 4.7 16.5 1.0
C2 B:EDO266 4.9 22.1 1.0
CB B:ASP45 4.9 15.2 1.0
C B:PRO46 4.9 16.9 1.0
N B:ARG49 4.9 10.2 1.0
O B:HOH593 5.0 33.2 1.0

Potassium binding site 4 out of 4 in 3qxz

Go back to Potassium Binding Sites List in 3qxz
Potassium binding site 4 out of 4 in the Crystal Structure of A Probable Enoyl-Coa Hydratase/Isomerase From Mycobacterium Abscessus


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Crystal Structure of A Probable Enoyl-Coa Hydratase/Isomerase From Mycobacterium Abscessus within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K262

b:11.8
occ:1.00
 O C:VAL48 2.7 12.7 1.0
O C:ASP45 2.7 15.8 1.0
O C:HOH395 2.7 17.9 1.0
O C:ASP43 2.8 12.3 1.0
O C:LEU42 2.8 11.5 1.0
OG1 C:THR95 2.9 10.7 1.0
C C:ASP43 3.4 12.8 1.0
C C:ASP45 3.7 16.8 1.0
CA C:ASP43 3.7 11.7 1.0
C C:VAL48 3.8 11.7 1.0
C C:LEU42 3.9 11.5 1.0
CB C:VAL48 3.9 12.7 1.0
C2 C:EDO266 4.0 14.2 1.0
CB C:THR95 4.1 9.1 1.0
N C:ASP45 4.1 15.3 1.0
O C:HOH376 4.2 36.0 1.0
CG2 C:THR95 4.2 10.9 1.0
CA C:VAL48 4.2 13.2 1.0
N C:ASP43 4.3 10.8 1.0
N C:VAL48 4.4 14.0 1.0
CG1 C:VAL48 4.4 12.9 1.0
N C:ASP44 4.4 13.8 1.0
CA C:ASP45 4.4 16.1 1.0
OD1 C:ASP43 4.5 11.4 1.0
O C:HOH444 4.5 18.6 1.0
N C:PRO46 4.6 18.5 1.0
C C:ASP44 4.6 15.8 1.0
CA C:PRO46 4.6 18.4 1.0
O2 C:EDO266 4.7 14.5 1.0
C C:PRO46 4.9 18.1 1.0
CB C:ASP45 4.9 15.5 1.0
N C:ARG49 4.9 11.3 1.0

Reference:

L.Baugh, I.Phan, D.W.Begley, M.C.Clifton, B.Armour, D.M.Dranow, B.M.Taylor, M.M.Muruthi, J.Abendroth, J.W.Fairman, D.Fox, S.H.Dieterich, B.L.Staker, A.S.Gardberg, R.Choi, S.N.Hewitt, A.J.Napuli, J.Myers, L.K.Barrett, Y.Zhang, M.Ferrell, E.Mundt, K.Thompkins, N.Tran, S.Lyons-Abbott, A.Abramov, A.Sekar, D.Serbzhinskiy, D.Lorimer, G.W.Buchko, R.Stacy, L.J.Stewart, T.E.Edwards, W.C.Van Voorhis, P.J.Myler. Increasing the Structural Coverage of Tuberculosis Drug Targets. Tuberculosis (Edinb) V. 95 142 2015.
ISSN: ISSN 1472-9792
PubMed: 25613812
DOI: 10.1016/J.TUBE.2014.12.003
Page generated: Mon Aug 12 09:16:21 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy