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Potassium in PDB 3phc: Crystal Structure of Plasmodium Falciparum Purine Nucleoside Phosphorylase in Complex with Dadme-Immg

Enzymatic activity of Crystal Structure of Plasmodium Falciparum Purine Nucleoside Phosphorylase in Complex with Dadme-Immg

All present enzymatic activity of Crystal Structure of Plasmodium Falciparum Purine Nucleoside Phosphorylase in Complex with Dadme-Immg:
2.4.2.1;

Protein crystallography data

The structure of Crystal Structure of Plasmodium Falciparum Purine Nucleoside Phosphorylase in Complex with Dadme-Immg, PDB code: 3phc was solved by M.Ho, A.A.Edwards, S.C.Almo, V.L.Schramm, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 2.00
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 61.197, 77.371, 92.197, 67.71, 73.62, 86.03
R / Rfree (%) 19.8 / 23.5

Potassium Binding Sites:

The binding sites of Potassium atom in the Crystal Structure of Plasmodium Falciparum Purine Nucleoside Phosphorylase in Complex with Dadme-Immg (pdb code 3phc). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Crystal Structure of Plasmodium Falciparum Purine Nucleoside Phosphorylase in Complex with Dadme-Immg, PDB code: 3phc:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in 3phc

Go back to Potassium Binding Sites List in 3phc
Potassium binding site 1 out of 3 in the Crystal Structure of Plasmodium Falciparum Purine Nucleoside Phosphorylase in Complex with Dadme-Immg


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Plasmodium Falciparum Purine Nucleoside Phosphorylase in Complex with Dadme-Immg within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K275

b:29.7
occ:1.00
OE1 B:GLU46 2.7 32.5 1.0
OE1 A:GLU46 2.7 33.2 1.0
O B:VAL66 2.8 26.8 1.0
O A:VAL66 2.9 26.8 1.0
O B:HOH304 3.1 35.1 1.0
N B:VAL66 3.5 26.9 1.0
N A:VAL66 3.6 26.6 1.0
O B:HOH277 3.7 25.5 1.0
C B:VAL66 3.7 26.9 1.0
C A:VAL66 3.8 26.5 1.0
CD B:GLU46 3.9 34.0 1.0
CD A:GLU46 3.9 34.4 1.0
C B:GLY65 4.1 26.9 1.0
CA B:VAL66 4.1 26.9 1.0
C A:GLY65 4.1 27.3 1.0
CA A:GLY65 4.2 27.0 1.0
CA A:VAL66 4.2 26.8 1.0
CA B:GLY65 4.3 26.3 1.0
CA A:GLY70 4.4 26.1 1.0
CG A:GLU46 4.4 32.4 1.0
CG B:GLU46 4.5 32.1 1.0
CA B:GLY70 4.5 25.9 1.0
CB B:VAL66 4.6 27.3 1.0
CB A:VAL66 4.7 27.2 1.0
N B:GLY67 4.8 26.7 1.0
O A:HIS64 4.9 27.8 1.0
OE2 B:GLU46 4.9 35.0 1.0
O B:HIS64 4.9 27.2 1.0
OE2 A:GLU46 4.9 32.4 1.0
N A:GLY67 4.9 26.3 1.0
N A:GLY70 4.9 26.4 1.0
O B:GLY65 5.0 26.4 1.0
O A:GLY65 5.0 27.1 1.0

Potassium binding site 2 out of 3 in 3phc

Go back to Potassium Binding Sites List in 3phc
Potassium binding site 2 out of 3 in the Crystal Structure of Plasmodium Falciparum Purine Nucleoside Phosphorylase in Complex with Dadme-Immg


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of Plasmodium Falciparum Purine Nucleoside Phosphorylase in Complex with Dadme-Immg within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K275

b:28.4
occ:1.00
OE1 C:GLU46 2.7 27.0 1.0
O C:VAL66 2.8 21.4 1.0
O D:VAL66 2.8 23.5 1.0
OE1 D:GLU46 2.8 30.3 1.0
O D:HOH291 2.9 34.3 1.0
N D:VAL66 3.6 22.6 1.0
N C:VAL66 3.6 21.5 1.0
O C:HOH278 3.6 23.4 1.0
C D:VAL66 3.8 23.0 1.0
C C:VAL66 3.8 21.3 1.0
CD C:GLU46 3.8 29.4 1.0
CD D:GLU46 3.9 30.8 1.0
C D:GLY65 4.1 22.9 1.0
CA D:VAL66 4.2 23.2 1.0
CA C:VAL66 4.2 21.6 1.0
C C:GLY65 4.2 22.1 1.0
CA D:GLY65 4.3 22.3 1.0
CA C:GLY65 4.3 22.4 1.0
CG C:GLU46 4.3 27.8 1.0
CG D:GLU46 4.4 28.5 1.0
CA C:GLY70 4.5 23.5 1.0
CA D:GLY70 4.6 21.0 1.0
CB D:VAL66 4.6 23.1 1.0
CB C:VAL66 4.6 21.7 1.0
OE2 C:GLU46 4.8 31.0 1.0
O D:HIS64 4.9 23.4 1.0
N D:GLY67 4.9 23.1 1.0
O C:HIS64 4.9 24.8 1.0
N C:GLY67 4.9 21.3 1.0
O D:GLY65 4.9 22.7 1.0
OE2 D:GLU46 5.0 33.4 1.0

Potassium binding site 3 out of 3 in 3phc

Go back to Potassium Binding Sites List in 3phc
Potassium binding site 3 out of 3 in the Crystal Structure of Plasmodium Falciparum Purine Nucleoside Phosphorylase in Complex with Dadme-Immg


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of Plasmodium Falciparum Purine Nucleoside Phosphorylase in Complex with Dadme-Immg within 5.0Å range:
probe atom residue distance (Å) B Occ
E:K275

b:24.9
occ:1.00
O E:HOH293 2.7 31.6 1.0
OE1 E:GLU46 2.7 26.5 1.0
OE1 F:GLU46 2.7 27.9 1.0
O E:VAL66 2.7 19.8 1.0
O F:VAL66 2.9 19.6 1.0
O F:HOH292 3.0 39.6 1.0
N E:VAL66 3.5 21.4 1.0
N F:VAL66 3.5 20.5 1.0
O F:HOH282 3.6 24.6 1.0
C E:VAL66 3.7 20.4 1.0
C F:VAL66 3.8 19.7 1.0
CD F:GLU46 3.9 28.9 1.0
CD E:GLU46 3.9 27.6 1.0
C E:GLY65 4.1 22.0 1.0
C F:GLY65 4.1 20.9 1.0
CA F:VAL66 4.1 20.1 1.0
CA E:GLY65 4.1 21.6 1.0
CA E:VAL66 4.1 21.2 1.0
CA F:GLY65 4.3 20.6 1.0
CG F:GLU46 4.4 26.3 1.0
CG E:GLU46 4.4 25.5 1.0
CA F:GLY70 4.5 23.7 1.0
CA E:GLY70 4.5 20.7 1.0
CB F:VAL66 4.5 20.1 1.0
CB E:VAL66 4.6 21.6 1.0
N E:GLY67 4.8 19.5 1.0
O E:HIS64 4.8 21.5 1.0
OE2 F:GLU46 4.9 29.9 1.0
O F:HIS64 4.9 22.9 1.0
OE2 E:GLU46 4.9 26.9 1.0
N F:GLY67 4.9 20.0 1.0
O F:GLY65 5.0 20.1 1.0
O E:GLY65 5.0 21.6 1.0

Reference:

M.Ho, A.A.Edwards, S.C.Almo, V.L.Schramm. Crystal Structure of Plasmodium Falciparum Purine Nucleoside Phosphorylase in Complex with Dadme-Immg To Be Published.
Page generated: Mon Aug 12 09:01:01 2024

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