Potassium in PDB 3p1c: Crystal Structure of the Bromodomain of Human Crebbp in Complex with Acetylated Lysine

All present enzymatic activity of Crystal Structure of the Bromodomain of Human Crebbp in Complex with Acetylated Lysine:
2.3.1.48;

The structure of Crystal Structure of the Bromodomain of Human Crebbp in Complex with Acetylated Lysine, PDB code: 3p1c was solved by P.Filippakopoulos, S.Picaud, I.Feletar, O.Fedorov, J.Muniz, F.Von Delft, C.H.Arrowsmith, A.M.Edwards, J.Weigelt, C.Bountra, S.Knapp, Structuralgenomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.83 / 1.82
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	121.687, 121.687, 39.955, 90.00, 90.00, 120.00
R / Rfree (%)	16.6 / 21.8

The binding sites of Potassium atom in the Crystal Structure of the Bromodomain of Human Crebbp in Complex with Acetylated Lysine (pdb code 3p1c). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Crystal Structure of the Bromodomain of Human Crebbp in Complex with Acetylated Lysine, PDB code: 3p1c:

Potassium binding site 1 out of 1 in the Crystal Structure of the Bromodomain of Human Crebbp in Complex with Acetylated Lysine


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of the Bromodomain of Human Crebbp in Complex with Acetylated Lysine within 5.0Å range: probe atom residue distance (Å) B Occ B:K1 b:48.3 occ:1.00 O B:HOH109 2.5 47.0 1.0 O B:ASN1168 2.7 29.1 1.0 O B:TRP1165 2.7 28.0 1.0 O B:LEU1166 3.0 30.0 1.0 C B:ASN1168 3.7 25.4 1.0 C B:LEU1166 3.7 30.6 1.0 C B:TRP1165 3.8 31.0 1.0 CA B:LEU1166 4.2 36.5 1.0 CA B:ARG1169 4.3 36.0 1.0 N B:ASN1168 4.3 24.8 1.0 N B:ARG1169 4.4 30.8 1.0 O B:HOH97 4.4 39.2 1.0 CE1 B:TYR1175 4.5 30.3 1.0 N B:LEU1166 4.5 30.7 1.0 C B:TYR1167 4.6 26.9 1.0 CD1 B:TYR1175 4.6 20.7 1.0 N B:TYR1167 4.6 30.1 1.0 CA B:ASN1168 4.7 27.4 1.0 C B:ARG1169 4.8 31.1 1.0 N B:LYS1170 4.8 28.2 1.0 O B:TYR1167 4.9 29.7 1.0 CA B:TRP1165 5.0 25.5 1.0 O B:HOH162 5.0 44.7 1.0

P.Filippakopoulos, S.Picaud, M.Mangos, T.Keates, J.P.Lambert, D.Barsyte-Lovejoy, I.Felletar, R.Volkmer, S.Muller, T.Pawson, A.C.Gingras, C.H.Arrowsmith, S.Knapp. Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family. Cell(Cambridge,Mass.) V. 149 214 2012.
ISSN: ISSN 0092-8674
PubMed: 22464331
DOI: 10.1016/J.CELL.2012.02.013