Potassium in PDB 3ous: Mthk Channel Pore T59A Mutant

The structure of Mthk Channel Pore T59A Mutant, PDB code: 3ous was solved by M.G.Derebe, D.B.Sauer, W.Zeng, A.Alam, N.Shi, Y.Jiang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.75
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	63.600, 63.600, 44.047, 90.00, 90.00, 90.00
R / Rfree (%)	21.2 / 23.6

The binding sites of Potassium atom in the Mthk Channel Pore T59A Mutant (pdb code 3ous). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 5 binding sites of Potassium where determined in the Mthk Channel Pore T59A Mutant, PDB code: 3ous:
Jump to Potassium binding site number: 1; 2; 3; 4; 5;

Potassium binding site 1 out of 5 in the Mthk Channel Pore T59A Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Mthk Channel Pore T59A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:K1 b:15.5 occ:0.25 O A:TYR62 3.1 16.0 1.0 O A:GLY61 3.2 18.3 1.0 K A:K2 3.5 16.2 0.2 C A:TYR62 3.5 18.1 1.0 CA A:TYR62 4.0 14.9 1.0 C A:GLY61 4.2 17.8 1.0 N A:GLY63 4.2 15.5 1.0 CA A:GLY63 4.5 16.0 1.0 N A:TYR62 4.6 15.1 1.0

Potassium binding site 2 out of 5 in the Mthk Channel Pore T59A Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Mthk Channel Pore T59A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:K2 b:16.2 occ:0.25 O A:VAL60 3.0 17.9 1.0 O A:GLY61 3.0 18.3 1.0 K A:K3 3.3 17.5 0.2 K A:K1 3.5 15.5 0.2 C A:GLY61 3.7 17.8 1.0 C A:VAL60 4.1 22.0 1.0 CA A:GLY61 4.1 15.9 1.0 N A:GLY61 4.5 18.1 1.0 N A:TYR62 4.5 15.1 1.0 CA A:TYR62 4.9 14.9 1.0

Potassium binding site 3 out of 5 in the Mthk Channel Pore T59A Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Mthk Channel Pore T59A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:K3 b:17.5 occ:0.25 O A:ALA59 3.0 23.5 1.0 O A:VAL60 3.3 17.9 1.0 K A:K2 3.3 16.2 0.2 K A:K4 3.7 38.2 0.2 C A:VAL60 3.8 22.0 1.0 C A:ALA59 4.0 20.3 1.0 CA A:VAL60 4.2 18.8 1.0 N A:VAL60 4.5 17.4 1.0 N A:GLY61 4.7 18.1 1.0

Potassium binding site 4 out of 5 in the Mthk Channel Pore T59A Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Mthk Channel Pore T59A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:K4 b:38.2 occ:0.25 K A:K5 2.8 66.6 0.2 O A:ALA59 3.2 23.5 1.0 O A:HOH151 3.3 46.9 1.0 K A:K3 3.7 17.5 0.2 CB A:ALA59 3.8 18.1 1.0 C A:ALA59 4.3 20.3 1.0 CA A:ALA59 4.7 15.5 1.0 O A:ALA58 4.9 20.6 1.0

Potassium binding site 5 out of 5 in the Mthk Channel Pore T59A Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Mthk Channel Pore T59A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:K5 b:66.6 occ:0.25 O A:HOH152 2.5 54.5 1.0 O A:HOH151 2.7 46.9 1.0 K A:K4 2.8 38.2 0.2 CB A:ALA59 4.9 18.1 1.0

M.G.Derebe, D.B.Sauer, W.Zeng, A.Alam, N.Shi, Y.Jiang. Tuning the Ion Selectivity of Tetrameric Cation Channels By Changing the Number of Ion Binding Sites. Proc.Natl.Acad.Sci.Usa V. 108 598 2011.
ISSN: ISSN 0027-8424
PubMed: 21187421
DOI: 10.1073/PNAS.1013636108