Potassium in PDB 3jzp: Human Mdmx Liganded with A 12MER Peptide Inhibitor (PDI6W)

The structure of Human Mdmx Liganded with A 12MER Peptide Inhibitor (PDI6W), PDB code: 3jzp was solved by E.Schonbrunn, J.Phan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.97 / 1.74
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	70.369, 27.632, 52.135, 90.00, 124.57, 90.00
R / Rfree (%)	16 / 21.7

The binding sites of Potassium atom in the Human Mdmx Liganded with A 12MER Peptide Inhibitor (PDI6W) (pdb code 3jzp). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Human Mdmx Liganded with A 12MER Peptide Inhibitor (PDI6W), PDB code: 3jzp:

Potassium binding site 1 out of 1 in the Human Mdmx Liganded with A 12MER Peptide Inhibitor (PDI6W)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human Mdmx Liganded with A 12MER Peptide Inhibitor (PDI6W) within 5.0Å range: probe atom residue distance (Å) B Occ A:K201 b:11.9 occ:1.00 O A:TYR66 2.8 13.2 1.0 O A:HOH12 2.8 16.4 1.0 O A:GLN64 2.8 10.5 1.0 O A:HOH123 2.9 23.9 1.0 C A:GLN64 3.8 9.7 1.0 C A:TYR66 3.9 12.2 1.0 C A:LEU65 4.2 11.0 1.0 O A:LEU65 4.3 12.0 1.0 N A:TYR66 4.4 10.3 1.0 CA A:LEU65 4.5 9.9 1.0 CB A:GLN64 4.5 14.4 1.0 N A:LEU65 4.6 9.0 1.0 N A:GLN68 4.6 11.8 1.0 N A:ASP67 4.7 11.1 1.0 CA A:GLN64 4.8 11.6 1.0 CA A:TYR66 4.8 10.9 1.0 CA A:ASP67 4.8 11.4 1.0

J.Phan, Z.Li, A.Kasprzak, B.Li, S.Sebti, W.Guida, E.Schonbrunn, J.Chen. Structure-Based Design of High Affinity Peptides Inhibiting the Interaction of P53 with MDM2 and Mdmx. J.Biol.Chem. V. 285 2174 2010.
ISSN: ISSN 0021-9258
PubMed: 19910468
DOI: 10.1074/JBC.M109.073056