Potassium in PDB 3idh: Human Pancreatic Glucokinase in Complex with Glucose

All present enzymatic activity of Human Pancreatic Glucokinase in Complex with Glucose:
2.7.1.2;

The structure of Human Pancreatic Glucokinase in Complex with Glucose, PDB code: 3idh was solved by P.Petit, L.Gluais, A.Lagarde, J.A.Boutin, G.Ferry, L.Vuillard, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	15.00 / 2.14
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	65.510, 81.970, 86.950, 90.00, 90.00, 90.00
R / Rfree (%)	18.9 / 22

The binding sites of Potassium atom in the Human Pancreatic Glucokinase in Complex with Glucose (pdb code 3idh). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Human Pancreatic Glucokinase in Complex with Glucose, PDB code: 3idh:

Potassium binding site 1 out of 1 in the Human Pancreatic Glucokinase in Complex with Glucose


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human Pancreatic Glucokinase in Complex with Glucose within 5.0Å range: probe atom residue distance (Å) B Occ A:K600 b:30.3 occ:1.00 O A:GLY246 2.5 28.1 1.0 O A:MET238 2.6 20.8 1.0 O A:VAL244 2.6 27.2 1.0 O A:VAL241 2.6 20.2 1.0 C A:VAL241 3.5 20.0 1.0 C A:GLY246 3.6 29.8 1.0 C A:MET238 3.7 20.5 1.0 C A:VAL244 3.8 27.0 1.0 N A:GLY246 3.9 29.8 1.0 OD2 A:ASP247 4.1 38.8 1.0 N A:GLU242 4.3 20.4 1.0 C A:GLU245 4.3 29.5 1.0 CA A:GLY246 4.4 30.3 1.0 CA A:VAL241 4.4 18.5 1.0 CA A:GLU242 4.4 21.6 1.0 CA A:GLN239 4.4 21.2 1.0 N A:VAL241 4.4 18.8 1.0 N A:GLN239 4.5 20.6 1.0 C A:GLN239 4.6 20.6 1.0 CE A:MET238 4.6 27.5 1.0 N A:ASP247 4.6 30.4 1.0 CB A:VAL241 4.6 18.4 1.0 CA A:MET238 4.7 20.6 1.0 N A:GLU245 4.7 28.6 1.0 CA A:GLU245 4.7 30.2 1.0 N A:VAL244 4.7 24.9 1.0 O A:GLN239 4.7 20.7 1.0 CA A:VAL244 4.8 25.7 1.0 C A:GLU242 4.8 22.4 1.0 CA A:ASP247 4.9 30.9 1.0 CB A:MET238 4.9 21.5 1.0 O A:GLU245 5.0 30.1 1.0

P.Petit, M.Antoine, G.Ferry, J.A.Boutin, A.Lagarde, L.Gluais, R.Vincentelli, L.Vuillard. The Active Conformation of Human Glucokinase Is Not Altered By Allosteric Activators Acta Crystallogr.,Sect.D V. 67 929 2011.
ISSN: ISSN 0907-4449
PubMed: 22101819
DOI: 10.1107/S0907444911036729