Potassium in PDB 3g71: Co-Crystal Structure of Bruceantin Bound to the Large Ribosomal Subunit

The structure of Co-Crystal Structure of Bruceantin Bound to the Large Ribosomal Subunit, PDB code: 3g71 was solved by G.Gurel, G.Blaha, P.B.Moore, T.A.Steitz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.76 / 2.85
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	212.207, 299.544, 574.251, 90.00, 90.00, 90.00
R / Rfree (%)	18.6 / 23.3

The structure of Co-Crystal Structure of Bruceantin Bound to the Large Ribosomal Subunit also contains other interesting chemical elements:

Strontium	(Sr)	108 atoms
Magnesium	(Mg)	93 atoms
Cadmium	(Cd)	5 atoms
Chlorine	(Cl)	22 atoms
Sodium	(Na)	75 atoms

The binding sites of Potassium atom in the Co-Crystal Structure of Bruceantin Bound to the Large Ribosomal Subunit (pdb code 3g71). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Co-Crystal Structure of Bruceantin Bound to the Large Ribosomal Subunit, PDB code: 3g71:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Co-Crystal Structure of Bruceantin Bound to the Large Ribosomal Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Co-Crystal Structure of Bruceantin Bound to the Large Ribosomal Subunit within 5.0Å range: probe atom residue distance (Å) B Occ 0:K8401 b:0.7 occ:1.00 O6 0:G2102 3.1 66.8 1.0 O6 0:G2482 3.4 45.9 1.0 OP1 0:U2539 3.4 46.5 1.0 O2 0:U2535 3.4 49.1 1.0 O 0:HOH3784 3.6 0.7 1.0 N7 0:G2482 3.6 45.3 1.0 O1L 0:WIN9101 3.6 0.2 1.0 O4' 0:C2536 3.7 43.1 1.0 N7 0:G2102 3.8 65.0 1.0 C2D 0:WIN9101 3.8 0.5 1.0 C6 0:G2102 4.0 66.1 1.0 C2' 0:U2535 4.0 46.8 1.0 C4' 0:C2536 4.0 44.4 1.0 C2 0:U2535 4.0 48.1 1.0 O2' 0:U2535 4.2 47.7 1.0 C6 0:G2482 4.2 45.3 1.0 O1M 0:WIN9101 4.2 0.4 1.0 C5 0:G2482 4.2 45.2 1.0 C2E 0:WIN9101 4.2 0.9 1.0 C5 0:G2102 4.2 66.2 1.0 O2 0:C2536 4.2 36.8 1.0 C5' 0:C2536 4.3 43.7 1.0 C1' 0:C2536 4.4 42.1 1.0 C1P 0:WIN9101 4.6 0.3 1.0 N1 0:U2535 4.7 47.3 1.0 N3 0:U2535 4.7 46.3 1.0 C8 0:G2482 4.7 44.2 1.0 C1' 0:U2535 4.7 46.3 1.0 P 0:U2539 4.8 50.8 1.0 C2 0:C2536 4.8 37.5 1.0 N1 0:C2536 4.9 39.8 1.0 C8 0:G2102 5.0 64.9 1.0 O5' 0:C2536 5.0 44.2 1.0

Potassium binding site 2 out of 2 in the Co-Crystal Structure of Bruceantin Bound to the Large Ribosomal Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Co-Crystal Structure of Bruceantin Bound to the Large Ribosomal Subunit within 5.0Å range: probe atom residue distance (Å) B Occ 0:K8402 b:90.2 occ:1.00 O 0:HOH2991 3.1 36.1 1.0 OP2 0:C162 3.1 32.4 1.0 O 0:HOH3347 3.2 58.9 1.0 O4 0:U163 3.3 35.9 1.0 O 0:HOH3480 3.3 49.8 1.0 O4 0:U172 3.4 45.3 1.0 O 0:HOH7790 3.7 0.2 1.0 O 0:HOH3817 3.7 90.5 1.0 MG 0:MG8041 3.7 32.6 1.0 CD M:ARG82 3.8 65.9 1.0 O 0:HOH4202 4.2 55.7 1.0 O 0:HOH7789 4.2 66.0 1.0 P 0:C162 4.3 33.6 1.0 C4 0:U172 4.3 42.7 1.0 C4 0:U163 4.3 35.6 1.0 OP2 0:A169 4.4 37.0 1.0 OP1 0:A169 4.4 36.0 1.0 N3 0:U172 4.4 42.6 1.0 N4 0:C171 4.5 37.9 1.0 CG M:ARG82 4.6 65.8 1.0 OP1 0:C162 4.6 31.8 1.0 CB M:ARG82 4.6 64.2 1.0 NE M:ARG82 4.6 64.6 1.0 C5 0:U163 4.7 35.2 1.0 P 0:A169 4.9 35.6 1.0 O6 0:G164 4.9 32.5 1.0

G.Gurel, G.Blaha, P.B.Moore, T.A.Steitz. U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics: the Structures of Tiamulin, Homoharringtonine, and Bruceantin Bound to the Ribosome. J.Mol.Biol. V. 389 146 2009.
ISSN: ISSN 0022-2836
PubMed: 19362093
DOI: 10.1016/J.JMB.2009.04.005