Potassium in PDB 3g4s: Co-Crystal Structure of Tiamulin Bound to the Large Ribosomal Subunit

The structure of Co-Crystal Structure of Tiamulin Bound to the Large Ribosomal Subunit, PDB code: 3g4s was solved by G.Gurel, G.Blaha, P.B.Moore, T.A.Steitz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.84 / 3.20
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	212.270, 299.840, 574.137, 90.00, 90.00, 90.00
R / Rfree (%)	21.5 / 29

The structure of Co-Crystal Structure of Tiamulin Bound to the Large Ribosomal Subunit also contains other interesting chemical elements:

Strontium	(Sr)	108 atoms
Magnesium	(Mg)	93 atoms
Cadmium	(Cd)	5 atoms
Chlorine	(Cl)	22 atoms
Sodium	(Na)	75 atoms

The binding sites of Potassium atom in the Co-Crystal Structure of Tiamulin Bound to the Large Ribosomal Subunit (pdb code 3g4s). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Co-Crystal Structure of Tiamulin Bound to the Large Ribosomal Subunit, PDB code: 3g4s:

Potassium binding site 1 out of 1 in the Co-Crystal Structure of Tiamulin Bound to the Large Ribosomal Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Co-Crystal Structure of Tiamulin Bound to the Large Ribosomal Subunit within 5.0Å range: probe atom residue distance (Å) B Occ 0:K8402 b:67.7 occ:1.00 O 0:HOH3458 3.1 44.4 1.0 O4 0:U172 3.2 58.7 1.0 O 0:HOH3319 3.3 53.2 1.0 NH1 M:ARG82 3.5 0.6 1.0 O 0:HOH2969 3.6 24.0 1.0 O 0:HOH7790 3.8 35.4 1.0 CD M:ARG82 3.9 0.4 1.0 O 0:HOH3817 4.0 83.7 1.0 CZ M:ARG82 4.0 0.3 1.0 OP2 0:C162 4.1 45.8 1.0 O 0:HOH4074 4.2 63.4 1.0 NE M:ARG82 4.2 0.8 1.0 C4 0:U172 4.4 56.0 1.0 OP2 0:U170 4.4 63.6 1.0 CG M:ARG82 4.5 0.8 1.0 OP1 0:A169 4.7 54.5 1.0 O4 0:U163 4.8 62.1 1.0 CB M:ARG82 4.8 0.8 1.0 OP1 0:A161 4.9 56.2 1.0 NH2 M:ARG82 4.9 0.4 1.0 OP2 0:A161 4.9 57.6 1.0 O5' 0:A161 4.9 52.2 1.0 N4 0:C171 5.0 64.5 1.0

G.Gurel, G.Blaha, P.B.Moore, T.A.Steitz. U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics: the Structures of Tiamulin, Homoharringtonine, and Bruceantin Bound to the Ribosome. J.Mol.Biol. V. 389 146 2009.
ISSN: ISSN 0022-2836
PubMed: 19362093
DOI: 10.1016/J.JMB.2009.04.005