Potassium in PDB 3ccv: Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2616A

The structure of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2616A, PDB code: 3ccv was solved by G.Blaha, G.Gurel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.99 / 2.90
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	211.752, 299.012, 574.480, 90.00, 90.00, 90.00
R / Rfree (%)	17.5 / 22.5

The structure of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2616A also contains other interesting chemical elements:

Strontium	(Sr)	108 atoms
Magnesium	(Mg)	93 atoms
Cadmium	(Cd)	5 atoms
Chlorine	(Cl)	22 atoms
Sodium	(Na)	75 atoms

The binding sites of Potassium atom in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2616A (pdb code 3ccv). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2616A, PDB code: 3ccv:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2616A


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2616A within 5.0Å range: probe atom residue distance (Å) B Occ 0:K8401 b:93.2 occ:1.00 O6 0:G2102 2.8 68.9 1.0 O6 0:G2482 3.0 40.7 1.0 N7 0:G2482 3.3 40.3 1.0 O4' 0:C2536 3.5 41.7 1.0 O2 0:C2536 3.5 39.0 1.0 C6 0:G2102 3.7 67.2 1.0 N7 0:G2102 3.7 66.6 1.0 C6 0:G2482 3.7 39.5 1.0 C5 0:G2482 3.9 39.6 1.0 O2 0:U2535 3.9 41.2 1.0 C1' 0:C2536 3.9 41.7 1.0 C5 0:G2102 4.0 66.9 1.0 C4' 0:C2536 4.1 41.8 1.0 N6 0:A2486 4.1 63.6 1.0 C2 0:C2536 4.1 39.6 1.0 N1 0:C2536 4.3 40.8 1.0 C2 0:U2535 4.4 41.0 1.0 OP1 0:U2539 4.4 68.2 1.0 C8 0:G2482 4.5 39.1 1.0 C5' 0:C2536 4.6 41.4 1.0 C2' 0:U2535 4.6 42.8 1.0 N3 0:U2535 4.7 38.6 1.0 C8 0:G2102 4.9 67.5 1.0 N1 0:G2102 4.9 65.7 1.0 O2' 0:U2535 5.0 42.0 1.0

Potassium binding site 2 out of 2 in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2616A


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2616A within 5.0Å range: probe atom residue distance (Å) B Occ 0:K8402 b:67.0 occ:1.00 O4 0:U163 2.9 34.5 1.0 O4 0:U172 3.0 37.0 1.0 O 0:HOH9116 3.1 40.0 1.0 O 0:HOH9151 3.1 21.6 1.0 O 0:HOH9020 3.2 23.5 1.0 OP2 0:C162 3.2 21.3 1.0 O 0:HOH4951 3.5 45.4 1.0 CD M:ARG82 3.6 42.5 1.0 O 0:HOH7831 3.6 39.6 1.0 O 0:HOH7830 3.7 50.6 1.0 C4 0:U172 3.8 33.4 1.0 N3 0:U172 3.8 32.9 1.0 C4 0:U163 3.9 32.7 1.0 O 0:HOH9334 4.0 38.6 1.0 N4 0:C171 4.3 28.2 1.0 NE M:ARG82 4.4 44.0 1.0 C5 0:U163 4.4 32.8 1.0 P 0:C162 4.5 23.6 1.0 OP2 0:A169 4.5 27.1 1.0 O6 0:G164 4.7 27.5 1.0 CG M:ARG82 4.7 42.8 1.0 MG 0:MG8041 4.8 29.2 1.0 CB M:ARG82 4.9 40.2 1.0 N3 0:C173 4.9 29.0 1.0 OP1 0:C162 4.9 22.2 1.0 OP1 0:A169 5.0 25.9 1.0

G.Blaha, G.Gurel, S.J.Schroeder, P.B.Moore, T.A.Steitz. Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant. J.Mol.Biol. V. 379 505 2008.
ISSN: ISSN 0022-2836
PubMed: 18455733
DOI: 10.1016/J.JMB.2008.03.075