Potassium in PDB 3ccm: Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2611U

The structure of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2611U, PDB code: 3ccm was solved by G.Blaha, G.Gurel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.70 / 2.55
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	211.531, 298.177, 573.367, 90.00, 90.00, 90.00
R / Rfree (%)	20.1 / 24

The structure of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2611U also contains other interesting chemical elements:

Strontium	(Sr)	108 atoms
Magnesium	(Mg)	93 atoms
Cadmium	(Cd)	5 atoms
Chlorine	(Cl)	22 atoms
Sodium	(Na)	75 atoms

The binding sites of Potassium atom in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2611U (pdb code 3ccm). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2611U, PDB code: 3ccm:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2611U


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2611U within 5.0Å range: probe atom residue distance (Å) B Occ 0:K8401 b:97.8 occ:1.00 O2 0:C2536 3.0 55.5 1.0 O4' 0:C2536 3.1 58.4 1.0 C1' 0:C2536 3.4 59.7 1.0 O6 0:G2482 3.5 55.5 1.0 O6 0:G2102 3.6 70.1 1.0 O 0:HOH4805 3.6 61.6 1.0 C2 0:C2536 3.8 55.5 1.0 N6 0:A2486 3.8 58.6 1.0 C4' 0:C2536 4.0 59.4 1.0 N1 0:C2536 4.0 56.8 1.0 N7 0:G2102 4.1 73.3 1.0 N7 0:G2482 4.3 52.7 1.0 C6 0:G2482 4.4 53.7 1.0 C6 0:G2102 4.5 71.5 1.0 C2' 0:C2536 4.7 61.0 1.0 N4 0:C2104 4.7 40.7 1.0 C5 0:G2102 4.7 72.8 1.0 O2' 0:C2536 4.7 63.0 1.0 C5 0:G2482 4.7 53.3 1.0 N3 0:C2104 4.8 40.9 1.0 C5' 0:C2536 4.8 55.6 1.0 N3 0:C2536 4.8 54.6 1.0 N6 0:A2485 4.9 50.1 1.0 O 0:HOH3524 5.0 54.0 1.0

Potassium binding site 2 out of 2 in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2611U


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation G2611U within 5.0Å range: probe atom residue distance (Å) B Occ 0:K8402 b:77.2 occ:1.00 O4 0:U172 2.9 24.1 1.0 O 0:HOH9022 3.0 17.3 1.0 CD M:ARG82 3.1 40.8 1.0 O4 0:U163 3.1 22.5 1.0 O M:HOH8824 3.1 28.6 1.0 O 0:HOH9124 3.2 36.9 1.0 OP2 0:C162 3.2 17.4 1.0 O 0:HOH7854 3.3 50.6 1.0 O 0:HOH4964 3.3 46.1 1.0 O 0:HOH9339 3.5 29.5 1.0 NE M:ARG82 3.8 42.6 1.0 C4 0:U172 3.8 23.2 1.0 N3 0:U172 4.0 22.0 1.0 O 0:HOH7853 4.1 48.5 1.0 C4 0:U163 4.2 19.4 1.0 CG M:ARG82 4.3 46.1 1.0 P 0:C162 4.4 17.4 1.0 N4 0:C171 4.6 28.5 1.0 C5 0:U163 4.7 19.6 1.0 CB M:ARG82 4.8 48.7 1.0 O6 0:G164 4.8 22.4 1.0 OP1 0:C162 4.8 18.8 1.0 CZ M:ARG82 4.8 45.3 1.0 OP2 0:A169 4.8 17.9 1.0 N3 0:C173 4.9 19.0 1.0 OP1 0:A169 4.9 20.8 1.0 MG 0:MG8041 4.9 52.4 1.0

G.Blaha, G.Gurel, S.J.Schroeder, P.B.Moore, T.A.Steitz. Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant. J.Mol.Biol. V. 379 505 2008.
ISSN: ISSN 0022-2836
PubMed: 18455733
DOI: 10.1016/J.JMB.2008.03.075