Potassium in PDB 3ccl: Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation U2535C. Density For Anisomycin Is Visible But Not Included in Model.

The structure of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation U2535C. Density For Anisomycin Is Visible But Not Included in Model., PDB code: 3ccl was solved by G.Blaha, G.Gurel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.98 / 2.90
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	213.161, 300.032, 576.127, 90.00, 90.00, 90.00
R / Rfree (%)	17.1 / 22

The structure of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation U2535C. Density For Anisomycin Is Visible But Not Included in Model. also contains other interesting chemical elements:

Strontium	(Sr)	108 atoms
Magnesium	(Mg)	93 atoms
Cadmium	(Cd)	5 atoms
Chlorine	(Cl)	22 atoms
Sodium	(Na)	75 atoms

The binding sites of Potassium atom in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation U2535C. Density For Anisomycin Is Visible But Not Included in Model. (pdb code 3ccl). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation U2535C. Density For Anisomycin Is Visible But Not Included in Model., PDB code: 3ccl:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation U2535C. Density For Anisomycin Is Visible But Not Included in Model.


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation U2535C. Density For Anisomycin Is Visible But Not Included in Model. within 5.0Å range: probe atom residue distance (Å) B Occ 0:K8401 b:74.4 occ:1.00 O6 0:G2482 2.7 46.3 1.0 O6 0:G2102 2.8 60.0 1.0 N7 0:G2482 2.9 46.3 1.0 O4' 0:C2536 3.0 50.1 1.0 O2 0:C2536 3.2 45.0 1.0 C6 0:G2482 3.4 45.3 1.0 C5 0:G2482 3.4 45.3 1.0 N7 0:G2102 3.5 56.4 1.0 C6 0:G2102 3.5 58.0 1.0 C1' 0:C2536 3.6 49.3 1.0 C2 0:C2536 3.7 46.0 1.0 C4' 0:C2536 3.8 49.1 1.0 C5 0:G2102 3.8 57.3 1.0 N1 0:C2536 3.9 47.9 1.0 N6 0:A2486 4.0 58.2 1.0 C8 0:G2482 4.1 46.8 1.0 C5' 0:C2536 4.2 48.8 1.0 O2 0:C2535 4.3 51.2 1.0 C2' 0:C2535 4.4 49.1 1.0 C2 0:C2535 4.6 48.3 1.0 OP1 0:U2539 4.6 56.1 1.0 N3 0:C2536 4.7 46.6 1.0 C8 0:G2102 4.7 56.5 1.0 O5' 0:C2536 4.7 48.9 1.0 N1 0:G2482 4.7 45.9 1.0 O2' 0:C2535 4.7 49.4 1.0 C4 0:G2482 4.8 45.5 1.0 N1 0:G2102 4.8 57.0 1.0 C6 0:C2536 4.9 48.0 1.0

Potassium binding site 2 out of 2 in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation U2535C. Density For Anisomycin Is Visible But Not Included in Model.


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation U2535C. Density For Anisomycin Is Visible But Not Included in Model. within 5.0Å range: probe atom residue distance (Å) B Occ 0:K8402 b:87.8 occ:1.00 O4 0:U172 2.9 44.8 1.0 O 0:HOH9022 2.9 30.2 1.0 O 0:HOH9156 3.0 35.9 1.0 O 0:HOH4963 3.0 75.9 1.0 O4 0:U163 3.1 45.1 1.0 O 0:HOH9120 3.2 42.4 1.0 OP2 0:C162 3.3 31.8 1.0 CD M:ARG82 3.4 51.1 1.0 O 0:HOH7848 3.4 51.4 1.0 C4 0:U172 3.8 41.9 1.0 N3 0:U172 3.9 41.9 1.0 O 0:HOH9340 4.1 45.4 1.0 NE M:ARG82 4.1 51.4 1.0 C4 0:U163 4.2 44.1 1.0 O 0:HOH7847 4.2 67.1 1.0 N4 0:C171 4.3 40.1 1.0 CG M:ARG82 4.5 51.6 1.0 OP2 0:A169 4.7 39.1 1.0 O6 0:G164 4.7 35.0 1.0 CB M:ARG82 4.7 49.8 1.0 P 0:C162 4.7 34.1 1.0 C5 0:U163 4.7 44.4 1.0 N3 0:C173 4.9 39.7 1.0 N4 0:C173 4.9 38.3 1.0 OP1 0:A169 5.0 36.3 1.0

G.Blaha, G.Gurel, S.J.Schroeder, P.B.Moore, T.A.Steitz. Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant. J.Mol.Biol. V. 379 505 2008.
ISSN: ISSN 0022-2836
PubMed: 18455733
DOI: 10.1016/J.JMB.2008.03.075