Potassium in PDB 3ccj: Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation C2534U

The structure of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation C2534U, PDB code: 3ccj was solved by G.Blaha, G.Gurel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 3.30
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	212.010, 299.254, 573.808, 90.00, 90.00, 90.00
R / Rfree (%)	20.8 / 28.7

The structure of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation C2534U also contains other interesting chemical elements:

Strontium	(Sr)	108 atoms
Magnesium	(Mg)	93 atoms
Cadmium	(Cd)	5 atoms
Chlorine	(Cl)	22 atoms
Sodium	(Na)	75 atoms

The binding sites of Potassium atom in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation C2534U (pdb code 3ccj). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation C2534U, PDB code: 3ccj:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation C2534U


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation C2534U within 5.0Å range: probe atom residue distance (Å) B Occ M:K8402 b:96.8 occ:1.00 O4 0:U172 2.8 51.9 1.0 O 0:HOH9125 2.8 42.7 1.0 O M:HOH8823 2.8 32.9 1.0 O 0:HOH7732 2.9 53.5 1.0 CZ M:ARG82 2.9 94.2 1.0 NE M:ARG82 3.0 95.3 1.0 O 0:HOH9022 3.0 41.5 1.0 NH1 M:ARG82 3.3 94.5 1.0 O4 0:U163 3.3 49.2 1.0 NH2 M:ARG82 3.3 92.6 1.0 OP2 0:C162 3.4 42.5 1.0 CD M:ARG82 3.6 97.9 1.0 C4 0:U172 3.8 50.2 1.0 N3 0:U172 4.1 48.6 1.0 O 0:HOH9337 4.3 76.8 1.0 N4 0:C171 4.4 61.0 1.0 C4 0:U163 4.4 50.6 1.0 P 0:C162 4.6 41.5 1.0 OP1 0:A169 4.6 41.9 1.0 O 0:HOH7733 4.8 24.5 1.0 OP2 0:A169 4.9 42.0 1.0 N3 0:C173 4.9 39.2 1.0 O6 0:G164 5.0 49.3 1.0 OP1 0:C162 5.0 40.1 1.0 N4 0:C173 5.0 38.6 1.0

Potassium binding site 2 out of 2 in the Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation C2534U


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of Anisomycin Resistant 50S Ribosomal Subunit: 23S Rrna Mutation C2534U within 5.0Å range: probe atom residue distance (Å) B Occ 0:K8401 b:0.9 occ:1.00 O6 0:G2102 2.6 88.1 1.0 O2 0:U2535 2.7 52.4 1.0 O 0:HOH9235 2.8 42.3 1.0 OP1 0:U2539 3.3 57.5 1.0 O6 0:G2482 3.4 52.4 1.0 C2 0:U2535 3.7 50.9 1.0 C6 0:G2102 3.8 86.7 1.0 O 0:HOH4750 4.2 36.6 1.0 C6 0:G2482 4.3 51.1 1.0 N3 0:U2535 4.3 48.2 1.0 N7 0:G2482 4.3 53.1 1.0 N7 0:G2102 4.5 83.8 1.0 O2' 0:U2535 4.5 50.8 1.0 C5 0:G2102 4.5 85.4 1.0 C2' 0:U2535 4.5 52.5 1.0 P 0:U2539 4.6 58.9 1.0 O4' 0:C2536 4.6 47.6 1.0 N6 0:A2486 4.7 68.2 1.0 C5 0:G2482 4.7 51.1 1.0 N1 0:U2535 4.7 51.7 1.0 C1' 0:U2535 4.8 52.1 1.0 O2 0:C2536 4.8 42.2 1.0 N1 0:G2102 4.9 86.6 1.0 C5 0:U2539 4.9 54.2 1.0 O3' 0:A2538 4.9 61.4 1.0 C6 0:U2539 4.9 54.1 1.0

G.Blaha, G.Gurel, S.J.Schroeder, P.B.Moore, T.A.Steitz. Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant. J.Mol.Biol. V. 379 505 2008.
ISSN: ISSN 0022-2836
PubMed: 18455733
DOI: 10.1016/J.JMB.2008.03.075