Potassium in PDB 3c33: Crystal Structure of GLUR5 Ligand-Binding Core in Complex with Potassium at 1.78 Angstrom Resolution

The structure of Crystal Structure of GLUR5 Ligand-Binding Core in Complex with Potassium at 1.78 Angstrom Resolution, PDB code: 3c33 was solved by M.L.Mayer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.31 / 1.72
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	70.742, 70.742, 234.460, 90.00, 90.00, 90.00
R / Rfree (%)	16.5 / 19.4

The structure of Crystal Structure of GLUR5 Ligand-Binding Core in Complex with Potassium at 1.78 Angstrom Resolution also contains other interesting chemical elements:

Chlorine

(Cl)

4 atoms

The binding sites of Potassium atom in the Crystal Structure of GLUR5 Ligand-Binding Core in Complex with Potassium at 1.78 Angstrom Resolution (pdb code 3c33). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Crystal Structure of GLUR5 Ligand-Binding Core in Complex with Potassium at 1.78 Angstrom Resolution, PDB code: 3c33:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Crystal Structure of GLUR5 Ligand-Binding Core in Complex with Potassium at 1.78 Angstrom Resolution


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of GLUR5 Ligand-Binding Core in Complex with Potassium at 1.78 Angstrom Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:K302 b:26.8 occ:1.00 O A:GLU96 2.6 11.8 1.0 OD1 A:ASP100 2.6 15.3 1.0 O A:ILE99 2.9 9.9 1.0 OE2 A:GLU96 2.9 23.3 1.0 O A:HOH409 2.9 44.2 1.0 O A:HOH408 3.0 25.3 1.0 O A:HOH407 3.5 24.0 1.0 O A:HOH606 3.7 38.5 1.0 C A:GLU96 3.7 10.5 1.0 CD1 A:ILE222 3.8 26.4 1.0 CG A:ASP100 3.8 16.0 1.0 C A:ILE99 3.8 9.4 1.0 CA A:ASP100 4.0 10.9 1.0 CD A:GLU96 4.1 21.4 1.0 CA A:GLU96 4.1 9.2 1.0 N A:ASP100 4.3 8.8 1.0 CB A:GLU96 4.4 10.5 1.0 CB A:ASP100 4.5 11.3 1.0 O B:HOH405 4.6 24.0 0.3 CD1 B:ILE232 4.6 17.1 1.0 OD2 A:ASP100 4.8 15.8 1.0 CG A:GLU96 4.8 14.6 1.0 N A:LYS97 4.8 9.4 1.0 CG B:ASP228 4.9 17.9 1.0 CG1 A:ILE222 4.9 19.9 1.0 N A:ILE99 5.0 7.6 1.0 CA A:ILE99 5.0 8.9 1.0

Potassium binding site 2 out of 3 in the Crystal Structure of GLUR5 Ligand-Binding Core in Complex with Potassium at 1.78 Angstrom Resolution


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of GLUR5 Ligand-Binding Core in Complex with Potassium at 1.78 Angstrom Resolution within 5.0Å range: probe atom residue distance (Å) B Occ B:K301 b:30.7 occ:1.00 O B:GLU96 2.5 12.7 1.0 OD1 B:ASP100 2.7 15.0 0.5 O B:ILE99 2.7 11.2 1.0 O B:HOH407 2.7 45.0 1.0 OD1 B:ASP100 2.9 14.5 0.5 OE1 B:GLU96 2.9 32.2 1.0 O A:HOH410 3.1 31.6 1.0 O B:HOH406 3.4 35.6 1.0 O B:HOH605 3.6 21.5 0.5 C B:GLU96 3.6 11.9 1.0 C B:ILE99 3.7 10.0 1.0 CG B:GLU96 3.8 20.9 1.0 CD B:GLU96 3.8 26.2 1.0 CG B:ASP100 3.8 13.4 0.5 CD1 B:ILE222 3.9 18.6 0.5 CA B:ASP100 4.0 10.7 0.5 CA B:ASP100 4.0 11.1 0.5 CG B:ASP100 4.0 13.4 0.5 N B:ASP100 4.2 9.8 0.5 CA B:GLU96 4.2 11.8 1.0 N B:ASP100 4.2 10.0 0.5 O B:HOH408 4.5 33.8 1.0 CB B:ASP100 4.5 10.9 0.5 CB B:GLU96 4.6 15.3 1.0 CB B:ASP100 4.6 10.6 0.5 CG1 B:ILE222 4.6 12.4 0.5 N B:LYS97 4.7 10.9 1.0 OD2 B:ASP100 4.8 13.0 0.5 CD1 A:ILE232 4.8 21.5 1.0 N B:ILE99 4.8 9.6 1.0 CA B:ILE99 4.8 9.0 1.0 C B:LYS97 4.9 13.3 1.0 CG1 B:ILE222 4.9 15.3 0.5 CA B:LYS97 4.9 12.9 1.0 OE2 B:GLU96 5.0 27.6 1.0

Potassium binding site 3 out of 3 in the Crystal Structure of GLUR5 Ligand-Binding Core in Complex with Potassium at 1.78 Angstrom Resolution


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of GLUR5 Ligand-Binding Core in Complex with Potassium at 1.78 Angstrom Resolution within 5.0Å range: probe atom residue distance (Å) B Occ B:K303 b:35.0 occ:1.00 O B:SER22 2.6 14.1 1.0 O B:HOH497 3.0 27.0 1.0 O B:HOH485 3.6 27.0 1.0 C B:SER22 3.8 14.2 1.0 O B:LYS24 4.1 11.7 1.0 C B:ASP23 4.2 13.6 0.5 O B:ASP23 4.2 14.8 0.5 N B:LYS24 4.4 13.3 1.0 CA B:ASP23 4.4 14.3 0.5 C B:ASP23 4.4 13.7 0.5 CA B:ASP23 4.5 14.1 0.5 C B:LYS24 4.5 11.7 1.0 N B:ASP23 4.6 13.9 0.5 N B:ASP23 4.6 13.8 0.5 N B:SER22 4.7 15.4 1.0 CA B:SER22 4.7 15.0 1.0 O B:HOH607 4.8 40.4 1.0 CA B:LYS24 4.9 13.0 1.0

A.J.Plested, R.Vijayan, P.C.Biggin, M.L.Mayer. Molecular Basis of Kainate Receptor Modulation By Sodium. Neuron V. 58 720 2008.
ISSN: ISSN 0896-6273
PubMed: 18549784
DOI: 10.1016/J.NEURON.2008.04.001