Potassium in PDB 2zxe: Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State

The structure of Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State, PDB code: 2zxe was solved by T.Shinoda, H.Ogawa, F.Cornelius, C.Toyoshima, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	15.00 / 2.40
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	223.815, 50.914, 163.786, 90.00, 105.12, 90.00
R / Rfree (%)	24.6 / 27.1

The structure of Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State also contains other interesting chemical elements:

Fluorine	(F)	4 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Potassium atom in the Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State (pdb code 2zxe). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State, PDB code: 2zxe:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State within 5.0Å range: probe atom residue distance (Å) B Occ A:K2003 b:47.3 occ:1.00 OD2 A:ASP811 2.7 44.6 1.0 OG A:SER782 2.7 44.1 1.0 O A:THR779 2.7 39.8 1.0 O A:HOH5010 2.7 49.5 1.0 OD1 A:ASN783 2.8 42.1 1.0 OD1 A:ASP811 3.2 45.6 1.0 CG A:ASP811 3.2 44.1 1.0 N A:ASN783 3.8 44.0 1.0 OE2 A:GLU786 3.8 49.4 1.0 C A:SER782 3.8 43.6 1.0 CG A:ASN783 3.8 43.3 1.0 CB A:SER782 3.9 43.3 1.0 C A:THR779 3.9 39.8 1.0 K A:K2004 4.1 47.2 1.0 OE1 A:GLU786 4.2 50.1 1.0 O A:SER782 4.2 43.9 1.0 O A:HOH5013 4.2 56.3 1.0 CA A:ASN783 4.2 44.2 1.0 CA A:SER782 4.3 43.3 1.0 CG2 A:THR779 4.3 39.0 1.0 CD A:GLU786 4.3 49.8 1.0 OD2 A:ASP815 4.4 44.3 1.0 CB A:ASP811 4.5 43.3 1.0 N A:SER782 4.5 42.8 1.0 CB A:ASN783 4.6 44.0 1.0 CA A:THR779 4.7 39.2 1.0 ND2 A:ASN783 4.7 42.7 1.0 N A:LEU780 4.8 40.3 1.0 CB A:PRO333 4.8 44.1 1.0 O A:LEU780 4.8 41.2 1.0 CA A:PRO333 4.9 44.0 1.0 CA A:LEU780 4.9 40.8 1.0 C A:LEU780 5.0 41.1 1.0

Potassium binding site 2 out of 3 in the Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State within 5.0Å range: probe atom residue distance (Å) B Occ A:K2004 b:47.2 occ:1.00 O A:VAL332 2.8 44.3 1.0 OD2 A:ASP811 2.9 44.6 1.0 OE2 A:GLU786 2.9 49.4 1.0 O A:VAL329 2.9 48.2 1.0 O A:ALA330 3.0 46.6 1.0 OD1 A:ASN783 3.0 42.1 1.0 OE1 A:GLU334 3.2 43.3 1.0 CG A:ASP811 3.5 44.1 1.0 C A:ALA330 3.6 46.9 1.0 OD1 A:ASP811 3.6 45.6 1.0 C A:VAL332 3.7 44.4 1.0 CG2 A:ILE807 3.9 44.7 1.0 CG A:ASN783 4.0 43.3 1.0 CA A:ALA330 4.0 47.2 1.0 CD A:GLU334 4.1 43.1 1.0 CD A:GLU786 4.1 49.8 1.0 C A:VAL329 4.1 48.6 1.0 K A:K2003 4.1 47.3 1.0 CA A:PRO333 4.1 44.0 1.0 OE2 A:GLU334 4.1 44.2 1.0 N A:PRO333 4.2 44.2 1.0 N A:ALA330 4.5 47.7 1.0 N A:VAL332 4.5 45.0 1.0 ND2 A:ASN783 4.6 42.7 1.0 N A:ASN331 4.6 46.3 1.0 CB A:ASP811 4.6 43.3 1.0 N A:GLU334 4.6 43.4 1.0 OE1 A:GLU786 4.6 50.1 1.0 C A:ASN331 4.7 45.6 1.0 CA A:VAL332 4.8 44.7 1.0 C A:PRO333 4.9 43.7 1.0 CA A:ASN783 4.9 44.2 1.0 CB A:ASN783 5.0 44.0 1.0

Potassium binding site 3 out of 3 in the Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State within 5.0Å range: probe atom residue distance (Å) B Occ A:K2005 b:42.8 occ:1.00 O A:ALA728 2.7 29.5 1.0 O A:LYS726 2.8 30.5 1.0 OD1 A:ASP747 3.0 38.1 1.0 O A:LEU725 3.0 28.2 1.0 O A:HOH5039 3.1 35.0 1.0 C A:LYS726 3.6 30.1 1.0 C A:ALA728 3.8 29.5 1.0 CG A:ASP747 3.8 36.5 1.0 OD2 A:ASP747 3.9 37.5 1.0 CA A:LYS726 4.0 29.9 1.0 N A:GLY731 4.0 27.8 1.0 C A:LEU725 4.1 28.5 1.0 N A:ALA728 4.3 29.6 1.0 O A:ASP729 4.4 29.7 1.0 C A:ASP729 4.4 29.4 1.0 CA A:ALA728 4.4 29.7 1.0 N A:LYS726 4.5 29.2 1.0 O A:ALA745 4.5 34.9 1.0 CA A:ILE730 4.5 28.8 1.0 N A:ILE730 4.5 28.9 1.0 N A:LYS727 4.6 29.9 1.0 C A:ILE730 4.6 28.4 1.0 C A:LYS727 4.6 29.8 1.0 CB A:ALA728 4.6 29.4 1.0 CA A:GLY731 4.8 27.6 1.0 N A:ASP729 4.8 29.5 1.0 O A:LYS727 5.0 29.8 1.0 CA A:ASP729 5.0 29.6 1.0

T.Shinoda, H.Ogawa, F.Cornelius, C.Toyoshima. Crystal Structure of the Sodium - Potassium Pump at 2.4 A Resolution Nature V. 459 446 2009.
ISSN: ISSN 0028-0836
PubMed: 19458722
DOI: 10.1038/NATURE07939