Potassium in PDB 2vdd: Crystal Structure of the Open State of Tolc Outer Membrane Component of Mutlidrug Efflux Pumps

The structure of Crystal Structure of the Open State of Tolc Outer Membrane Component of Mutlidrug Efflux Pumps, PDB code: 2vdd was solved by V.N.Bavro, Z.Pietras, N.Furnham, L.Perez-Cano, J.Fernandez-Recio, X.Y.Pei, R.Truer, R.Misra, B.Luisi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.80 / 3.30
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	122.485, 70.966, 219.951, 90.00, 100.61, 90.00
R / Rfree (%)	23.6 / 29.5

The structure of Crystal Structure of the Open State of Tolc Outer Membrane Component of Mutlidrug Efflux Pumps also contains other interesting chemical elements:

Chlorine

(Cl)

3 atoms

The binding sites of Potassium atom in the Crystal Structure of the Open State of Tolc Outer Membrane Component of Mutlidrug Efflux Pumps (pdb code 2vdd). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Crystal Structure of the Open State of Tolc Outer Membrane Component of Mutlidrug Efflux Pumps, PDB code: 2vdd:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Crystal Structure of the Open State of Tolc Outer Membrane Component of Mutlidrug Efflux Pumps


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of the Open State of Tolc Outer Membrane Component of Mutlidrug Efflux Pumps within 5.0Å range: probe atom residue distance (Å) B Occ A:K1455 b:66.8 occ:1.00 CZ A:TYR329 4.1 21.2 1.0 OE1 A:GLN328 4.2 23.4 1.0 OH A:TYR329 4.2 20.8 1.0 CB A:GLN328 4.3 21.1 1.0 CE2 A:TYR329 4.4 21.4 1.0 CE1 A:TYR329 4.4 21.6 1.0 CD A:GLN328 4.6 22.7 1.0 CG A:LYS325 4.6 25.2 1.0 O A:LYS325 4.8 23.9 1.0 CD2 A:TYR329 4.9 21.2 1.0 CD1 A:TYR329 4.9 21.3 1.0

Potassium binding site 2 out of 3 in the Crystal Structure of the Open State of Tolc Outer Membrane Component of Mutlidrug Efflux Pumps


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of the Open State of Tolc Outer Membrane Component of Mutlidrug Efflux Pumps within 5.0Å range: probe atom residue distance (Å) B Occ A:K1456 b:68.2 occ:1.00 CE1 A:TYR76 4.2 49.2 1.0 CD1 A:TYR76 4.2 49.1 1.0 CZ A:TYR76 4.3 49.1 1.0 CG A:TYR76 4.3 49.2 1.0 CE2 A:TYR76 4.4 49.1 1.0 CD2 A:TYR76 4.4 49.2 1.0 ND2 C:ASN304 4.7 36.2 1.0 OH A:TYR76 4.9 49.0 1.0

Potassium binding site 3 out of 3 in the Crystal Structure of the Open State of Tolc Outer Membrane Component of Mutlidrug Efflux Pumps


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of the Open State of Tolc Outer Membrane Component of Mutlidrug Efflux Pumps within 5.0Å range: probe atom residue distance (Å) B Occ C:K1455 b:79.2 occ:1.00 CZ C:TYR76 4.3 44.9 1.0 CE2 C:TYR76 4.3 44.9 1.0 CE1 C:TYR76 4.4 44.9 1.0 CD2 C:TYR76 4.4 44.8 1.0 CD1 C:TYR76 4.5 44.9 1.0 CG C:TYR76 4.5 44.9 1.0 OH C:TYR76 4.8 44.6 1.0 NH1 C:ARG77 4.9 46.3 1.0

V.N.Bavro, Z.Pietras, N.Furnham, L.Perez-Cano, J.Fernandez-Recio, X.Y.Pei, R.Truer, R.Misra, B.Luisi. Assembly and Channel Opening in A Bacterial Drug Efflux Machine. Mol.Cell V. 30 114 2008.
ISSN: ISSN 1097-2765
PubMed: 18406332
DOI: 10.1016/J.MOLCEL.2008.02.015