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Potassium in PDB 2sge: Glu 18 Variant of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces Griseus Proteinase B at pH 10.7

Enzymatic activity of Glu 18 Variant of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces Griseus Proteinase B at pH 10.7

All present enzymatic activity of Glu 18 Variant of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces Griseus Proteinase B at pH 10.7:
3.4.21.81;

Protein crystallography data

The structure of Glu 18 Variant of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces Griseus Proteinase B at pH 10.7, PDB code: 2sge was solved by K.Huang, W.Lu, S.Anderson, M.Laskowski Jr., M.N.G.James, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 1.80
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 45.670, 54.840, 45.740, 90.00, 119.32, 90.00
R / Rfree (%) n/a / n/a

Potassium Binding Sites:

The binding sites of Potassium atom in the Glu 18 Variant of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces Griseus Proteinase B at pH 10.7 (pdb code 2sge). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Glu 18 Variant of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces Griseus Proteinase B at pH 10.7, PDB code: 2sge:

Potassium binding site 1 out of 1 in 2sge

Go back to Potassium Binding Sites List in 2sge
Potassium binding site 1 out of 1 in the Glu 18 Variant of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces Griseus Proteinase B at pH 10.7


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Glu 18 Variant of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces Griseus Proteinase B at pH 10.7 within 5.0Å range:
probe atom residue distance (Å) B Occ
E:K501

b:18.3
occ:1.00
O E:ALA192 2.6 8.3 1.0
O E:HOH591 2.7 18.6 1.0
OE2 I:GLU18 2.7 17.5 1.0
O I:HOH71 2.9 20.0 1.0
O E:GLY218 2.9 16.4 1.0
O I:HOH87 3.0 36.0 1.0
O E:HOH529 3.4 13.9 1.0
CD I:GLU18 3.5 18.1 1.0
OE1 I:GLU18 3.6 21.7 1.0
C E:ALA192 3.7 5.0 1.0
O I:HOH86 3.8 17.9 1.0
C E:GLY218 3.9 9.4 1.0
C E:SER217 4.1 13.8 1.0
O E:SER217 4.2 14.2 1.0
N E:SER217 4.4 10.2 1.0
N E:GLY218 4.4 14.3 1.0
CA E:GLU192A 4.4 7.2 1.0
CA E:SER217 4.4 8.4 1.0
N E:GLU192A 4.4 5.5 1.0
C E:GLY216 4.5 9.6 1.0
O E:GLY216 4.6 7.7 1.0
CA E:ALA192 4.7 3.0 1.0
N E:ASN219 4.7 8.6 1.0
CA E:ASN219 4.7 9.5 1.0
N E:ALA192 4.7 6.8 1.0
OD1 I:ASN36 4.7 20.9 1.0
CA E:GLY218 4.8 11.6 1.0
CG I:GLU18 4.9 12.9 1.0
CG E:GLU192A 4.9 12.1 1.0
CD E:PRO192B 4.9 5.5 1.0
CB E:ALA192 5.0 3.4 1.0

Reference:

K.Huang, W.Lu, S.Anderson, M.Laskowski, M.N.James. Water Molecules Participate in Proteinase-Inhibitor Interactions: Crystal Structures of LEU18, ALA18, and GLY18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces Griseus Proteinase B. Protein Sci. V. 4 1985 1995.
ISSN: ISSN 0961-8368
PubMed: 8535235
DOI: 10.1002/PRO.5560041004
Page generated: Mon Aug 12 06:57:26 2024

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