Atomistry » Potassium » PDB 2hzv-2o84 » 2iby
Atomistry »
  Potassium »
    PDB 2hzv-2o84 »
      2iby »

Potassium in PDB 2iby: Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function

Enzymatic activity of Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function

All present enzymatic activity of Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function:
2.3.1.9;

Protein crystallography data

The structure of Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function, PDB code: 2iby was solved by A.M.Haapalainen, R.K.Wierenga, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 73.32 / 1.85
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 75.349, 106.746, 101.660, 90.00, 103.06, 90.00
R / Rfree (%) 16.4 / 20.3

Other elements in 2iby:

The structure of Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function also contains other interesting chemical elements:

Chlorine (Cl) 4 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function (pdb code 2iby). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function, PDB code: 2iby:
Jump to Potassium binding site number: 1; 2; 3; 4;

Potassium binding site 1 out of 4 in 2iby

Go back to Potassium Binding Sites List in 2iby
Potassium binding site 1 out of 4 in the Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K3001

b:13.0
occ:1.00
 O A:ALA283 2.7 9.9 1.0
O A:ALA281 2.7 11.6 1.0
OH A:TYR219 2.7 13.4 1.0
O A:VAL381 2.8 11.9 1.0
O A:HOH6143 2.8 18.5 1.0
O A:ALA280 3.0 14.3 1.0
C A:ALA281 3.4 12.4 1.0
CA A:ALA281 3.8 13.8 1.0
CG2 A:THR285 3.8 14.9 1.0
CZ A:TYR219 3.8 13.2 1.0
C A:VAL381 3.9 13.1 1.0
C A:ALA283 3.9 11.7 1.0
CG1 A:VAL381 4.0 12.9 1.0
C A:ALA280 4.1 16.8 1.0
CE2 A:TYR219 4.1 12.9 1.0
O A:HOH6048 4.3 15.8 1.0
O A:HOH6080 4.3 15.8 1.0
N A:ASN282 4.4 8.9 1.0
N A:ALA281 4.4 13.3 1.0
CA A:VAL381 4.4 12.8 1.0
N6A A:COA6001 4.4 29.9 1.0
N A:ALA283 4.5 11.3 1.0
C A:SER284 4.7 11.9 1.0
CA A:SER284 4.8 10.1 1.0
CB A:VAL381 4.8 11.8 1.0
N A:SER284 4.8 12.1 1.0
CA A:ALA283 4.9 11.7 1.0
N A:THR285 4.9 11.7 1.0
C A:ASN282 4.9 10.7 1.0
CA A:ASN282 4.9 10.0 1.0
N A:SER382 5.0 12.5 1.0

Potassium binding site 2 out of 4 in 2iby

Go back to Potassium Binding Sites List in 2iby
Potassium binding site 2 out of 4 in the Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K3002

b:15.1
occ:1.00
 O B:ALA283 2.7 14.3 1.0
O B:VAL381 2.7 11.9 1.0
O B:ALA281 2.8 13.3 1.0
OH B:TYR219 2.8 13.6 1.0
O B:HOH6051 2.8 15.9 1.0
O B:ALA280 3.0 13.8 1.0
C B:ALA281 3.4 12.1 1.0
CG2 B:THR285 3.7 17.0 1.0
CA B:ALA281 3.8 14.3 1.0
CZ B:TYR219 3.9 14.1 1.0
C B:VAL381 3.9 10.3 1.0
C B:ALA283 3.9 14.2 1.0
CG1 B:VAL381 3.9 15.3 1.0
C B:ALA280 4.0 17.8 1.0
CE2 B:TYR219 4.1 12.9 1.0
O B:HOH6055 4.1 19.2 1.0
O B:HOH6073 4.4 15.7 1.0
N B:ASN282 4.4 13.4 1.0
N B:ALA281 4.4 15.7 1.0
CA B:VAL381 4.4 10.3 1.0
N B:ALA283 4.5 14.4 1.0
N6A B:COA6002 4.5 30.5 1.0
C B:SER284 4.7 14.5 1.0
CA B:SER284 4.8 13.8 1.0
CB B:VAL381 4.8 13.4 1.0
N B:THR285 4.8 14.8 1.0
N B:SER284 4.8 12.8 1.0
CA B:ALA283 4.8 13.9 1.0
C B:ASN282 4.9 14.2 1.0
CA B:ASN282 4.9 12.8 1.0
N B:SER382 5.0 10.7 1.0
O B:SER284 5.0 14.7 1.0
CB B:THR285 5.0 14.2 1.0

Potassium binding site 3 out of 4 in 2iby

Go back to Potassium Binding Sites List in 2iby
Potassium binding site 3 out of 4 in the Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K3003

b:28.2
occ:1.00
 O C:ALA283 2.7 25.9 1.0
O C:ALA281 2.7 28.6 1.0
O C:HOH6070 2.7 27.2 1.0
O C:VAL381 2.8 29.7 1.0
OH C:TYR219 2.9 27.6 1.0
O C:ALA280 3.0 30.1 1.0
C C:ALA281 3.4 29.3 1.0
CG2 C:THR285 3.7 27.9 1.0
CA C:ALA281 3.8 29.4 1.0
C C:ALA283 3.9 25.9 1.0
C C:VAL381 3.9 28.4 1.0
CZ C:TYR219 4.0 29.2 1.0
C C:ALA280 4.0 30.7 1.0
CG1 C:VAL381 4.1 28.0 1.0
O C:HOH6134 4.2 37.2 1.0
CE2 C:TYR219 4.2 28.4 1.0
O C:HOH6082 4.2 30.3 1.0
N C:ALA283 4.3 28.3 1.0
N C:ALA281 4.4 29.7 1.0
N C:ASN282 4.4 29.3 1.0
CA C:VAL381 4.5 28.1 1.0
N6A C:COA6003 4.6 49.1 1.0
C C:SER284 4.7 21.5 1.0
CA C:ALA283 4.8 27.0 1.0
CA C:SER284 4.8 22.6 1.0
N C:SER284 4.8 24.3 1.0
N C:THR285 4.9 24.3 1.0
C C:ASN282 4.9 29.6 1.0
O C:SER284 4.9 20.9 1.0
CA C:ASN282 4.9 29.9 1.0
CB C:VAL381 4.9 26.6 1.0

Potassium binding site 4 out of 4 in 2iby

Go back to Potassium Binding Sites List in 2iby
Potassium binding site 4 out of 4 in the Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase (T2): the Importance of Potassium and Chloride For Its Structure and Function within 5.0Å range:
probe atom residue distance (Å) B Occ
D:K3004

b:26.3
occ:1.00
 O D:VAL381 2.7 24.6 1.0
O D:ALA283 2.7 22.5 1.0
O D:HOH6044 2.8 29.6 1.0
OH D:TYR219 2.8 27.4 1.0
O D:ALA281 3.0 29.7 1.0
O D:ALA280 3.0 32.4 1.0
C D:ALA281 3.6 29.4 1.0
C D:VAL381 3.9 24.4 1.0
CG2 D:THR285 3.9 25.7 1.0
CZ D:TYR219 3.9 26.4 1.0
CA D:ALA281 3.9 30.9 1.0
C D:ALA283 4.0 25.1 1.0
CG1 D:VAL381 4.1 24.6 1.0
C D:ALA280 4.1 32.0 1.0
CE2 D:TYR219 4.3 25.6 1.0
O D:HOH6096 4.3 32.7 1.0
O D:HOH6068 4.3 29.2 1.0
CA D:VAL381 4.4 25.3 1.0
N D:ALA283 4.5 28.4 1.0
N D:ASN282 4.5 28.1 1.0
N6A D:COA6004 4.5 59.8 1.0
N D:ALA281 4.5 31.2 1.0
C D:SER284 4.8 25.8 1.0
CA D:SER284 4.8 25.6 1.0
CB D:VAL381 4.8 26.1 1.0
N D:SER284 4.8 23.4 1.0
N D:THR285 4.8 25.6 1.0
CA D:ALA283 4.9 25.3 1.0
N D:SER382 5.0 26.0 1.0

Reference:

A.M.Haapalainen, G.Merilainen, P.L.Pirila, N.Kondo, T.Fukao, R.K.Wierenga. Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-Coa Thiolase: the Importance of Potassium and Chloride Ions For Its Structure and Function Biochemistry V. 46 4305 2007.
ISSN: ISSN 0006-2960
PubMed: 17371050
DOI: 10.1021/BI6026192
Page generated: Mon Aug 12 06:38:47 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy