Potassium in PDB 2hjf: Potassium Channel Kcsa-Fab Complex with Tetrabutylammonium (Tba)

The structure of Potassium Channel Kcsa-Fab Complex with Tetrabutylammonium (Tba), PDB code: 2hjf was solved by J.D.Faraldo-Gomez, E.Kutluay, V.Jogini, Y.Zhao, L.Heginbotham, B.Roux, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.90
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	156.200, 156.200, 76.316, 90.00, 90.00, 90.00
R / Rfree (%)	22.5 / 28.4

The binding sites of Potassium atom in the Potassium Channel Kcsa-Fab Complex with Tetrabutylammonium (Tba) (pdb code 2hjf). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Potassium Channel Kcsa-Fab Complex with Tetrabutylammonium (Tba), PDB code: 2hjf:
Jump to Potassium binding site number: 1; 2; 3; 4;

Potassium binding site 1 out of 4 in the Potassium Channel Kcsa-Fab Complex with Tetrabutylammonium (Tba)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Potassium Channel Kcsa-Fab Complex with Tetrabutylammonium (Tba) within 5.0Å range: probe atom residue distance (Å) B Occ C:K3001 b:41.4 occ:0.25 O C:TYR78 3.2 18.8 1.0 K C:K3002 3.4 19.0 0.2 C C:TYR78 3.7 18.4 1.0 O C:GLY77 3.9 15.9 1.0 CA C:TYR78 4.3 19.0 1.0 N C:GLY79 4.4 18.0 1.0 CA C:GLY79 4.6 18.2 1.0 C C:GLY77 4.9 16.6 1.0

Potassium binding site 2 out of 4 in the Potassium Channel Kcsa-Fab Complex with Tetrabutylammonium (Tba)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Potassium Channel Kcsa-Fab Complex with Tetrabutylammonium (Tba) within 5.0Å range: probe atom residue distance (Å) B Occ C:K3002 b:19.0 occ:0.25 K C:K3003 3.2 14.6 0.2 O C:GLY77 3.2 15.9 1.0 O C:VAL76 3.3 12.0 1.0 K C:K3001 3.4 41.4 0.2 C C:GLY77 4.2 16.6 1.0 C C:VAL76 4.4 14.1 1.0

Potassium binding site 3 out of 4 in the Potassium Channel Kcsa-Fab Complex with Tetrabutylammonium (Tba)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Potassium Channel Kcsa-Fab Complex with Tetrabutylammonium (Tba) within 5.0Å range: probe atom residue distance (Å) B Occ C:K3003 b:14.6 occ:0.25 O C:THR75 3.1 18.8 1.0 O C:VAL76 3.2 12.0 1.0 K C:K3002 3.2 19.0 0.2 K C:K3004 3.3 33.5 0.2 C C:VAL76 4.0 14.1 1.0 CA C:VAL76 4.1 13.8 1.0 C C:THR75 4.2 18.4 1.0 N C:VAL76 4.7 15.6 1.0

Potassium binding site 4 out of 4 in the Potassium Channel Kcsa-Fab Complex with Tetrabutylammonium (Tba)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Potassium Channel Kcsa-Fab Complex with Tetrabutylammonium (Tba) within 5.0Å range: probe atom residue distance (Å) B Occ C:K3004 b:33.5 occ:0.25 K C:K3003 3.3 14.6 0.2 OG1 C:THR75 3.4 20.9 1.0 O C:THR75 3.4 18.8 1.0 CB C:THR75 3.8 21.1 1.0 C11 C:TBA1 4.1 12.0 0.2 C C:THR75 4.1 18.4 1.0 C41 C:TBA1 4.4 12.0 0.2 CA C:THR75 4.7 20.4 1.0 C42 C:TBA1 4.8 12.0 0.2 CG2 C:THR75 4.9 20.7 1.0 N1 C:TBA1 4.9 14.0 0.2 N C:VAL76 5.0 15.6 1.0

J.D.Faraldo-Gomez, E.Kutluay, V.Jogini, Y.Zhao, L.Heginbotham, B.Roux. Mechanism of Intracellular Block of the Kcsa K(+) Channel By Tetrabutylammonium: Insights From X-Ray Crystallography, Electrophysiology and Replica-Exchange Molecular Dynamics Simulations. J.Mol.Biol. V. 365 649 2007.
ISSN: ISSN 0022-2836
PubMed: 17070844
DOI: 10.1016/J.JMB.2006.09.069