Potassium in PDB 2fcx: Hiv-1 Dis Kissing-Loop in Complex with Neamine

The structure of Hiv-1 Dis Kissing-Loop in Complex with Neamine, PDB code: 2fcx was solved by E.Ennifar, J.C.Paillart, R.Marquet, P.Dumas, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.42 / 2.00
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	27.005, 113.395, 95.038, 90.00, 90.00, 90.00
R / Rfree (%)	26.7 / 29.2

The structure of Hiv-1 Dis Kissing-Loop in Complex with Neamine also contains other interesting chemical elements:

Bromine	(Br)	2 atoms
Chlorine	(Cl)	1 atom

The binding sites of Potassium atom in the Hiv-1 Dis Kissing-Loop in Complex with Neamine (pdb code 2fcx). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Hiv-1 Dis Kissing-Loop in Complex with Neamine, PDB code: 2fcx:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Hiv-1 Dis Kissing-Loop in Complex with Neamine


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Hiv-1 Dis Kissing-Loop in Complex with Neamine within 5.0Å range: probe atom residue distance (Å) B Occ A:K24 b:53.3 occ:0.93 O6 A:G4 2.7 36.9 1.0 O4 A:5BU3 2.9 29.0 1.0 C4 A:5BU3 3.6 30.4 1.0 BR A:5BU3 3.8 25.8 0.3 C6 A:G4 3.8 39.0 1.0 C5 A:5BU3 4.1 28.4 1.0 O A:HOH116 4.1 46.2 1.0 N4 A:C20 4.2 44.3 1.0 N7 A:G4 4.3 41.4 1.0 N4 A:C5 4.3 45.4 1.0 N6 A:A21 4.3 39.0 1.0 C5 A:G4 4.4 40.2 1.0 O6 A:G19 4.5 48.7 1.0 N3 A:5BU3 4.6 26.7 1.0 O A:HOH117 4.8 38.4 1.0

Potassium binding site 2 out of 3 in the Hiv-1 Dis Kissing-Loop in Complex with Neamine


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Hiv-1 Dis Kissing-Loop in Complex with Neamine within 5.0Å range: probe atom residue distance (Å) B Occ A:K25 b:48.2 occ:0.92 OP1 A:A8 2.4 58.8 1.0 OP2 A:A9 2.9 40.7 1.0 O7 A:XXX101 3.0 44.8 1.0 P A:A8 3.7 57.7 1.0 O5' A:A8 4.1 54.2 1.0 C13 A:XXX101 4.1 44.6 1.0 C14 A:XXX101 4.2 43.7 1.0 P A:A9 4.2 42.3 1.0 O8 A:XXX101 4.3 40.9 1.0 OP2 A:A8 4.4 57.9 1.0 OP1 A:A9 4.7 46.2 1.0 O3' A:A8 4.7 41.1 1.0 C11 A:XXX101 4.8 45.5 1.0 O3' A:G7 4.9 56.5 1.0

Potassium binding site 3 out of 3 in the Hiv-1 Dis Kissing-Loop in Complex with Neamine


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Hiv-1 Dis Kissing-Loop in Complex with Neamine within 5.0Å range: probe atom residue distance (Å) B Occ B:K24 b:64.8 occ:0.79 O6 B:G4 2.4 47.5 1.0 O4 B:5BU3 2.7 51.1 1.0 O B:HOH217 3.3 62.6 1.0 C4 B:5BU3 3.4 47.9 1.0 C6 B:G4 3.5 45.5 1.0 N6 B:A21 3.8 57.1 1.0 N4 B:C20 3.9 69.6 1.0 O B:HOH216 4.0 52.1 1.0 C5 B:5BU3 4.0 49.8 1.0 BR B:5BU3 4.1 44.1 0.4 O6 B:G19 4.1 55.3 1.0 N7 B:G4 4.1 45.5 1.0 N3 B:5BU3 4.1 48.8 1.0 C5 B:G4 4.2 45.3 1.0 N4 B:C5 4.4 39.4 1.0 N1 B:G4 4.7 46.1 1.0 C6 B:A21 4.7 58.7 1.0

E.Ennifar, J.C.Paillart, A.Bodlenner, P.Walter, J.-M.Weibel, A.-M.Aubertin, P.Pale, P.Dumas, R.Marquet. Targeting the Dimerization Initiation Site of Hiv-1 Rna with Aminoglycosides: From Crystal to Cell. Nucleic Acids Res. V. 34 2328 2006.
ISSN: ISSN 0305-1048
PubMed: 16679451
DOI: 10.1093/NAR/GKL317