Potassium in PDB 2atk: Structure of A Mutant Kcsa K+ Channel

The structure of Structure of A Mutant Kcsa K+ Channel, PDB code: 2atk was solved by J.F.Cordero-Morales, L.G.Cuello, Y.Zhao, V.Jogini, S.Chakrapani, B.Roux, E.Perozo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.50
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	155.160, 155.160, 75.712, 90.00, 90.00, 90.00
R / Rfree (%)	23.8 / 26.1

The binding sites of Potassium atom in the Structure of A Mutant Kcsa K+ Channel (pdb code 2atk). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 7 binding sites of Potassium where determined in the Structure of A Mutant Kcsa K+ Channel, PDB code: 2atk:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6; 7;

Potassium binding site 1 out of 7 in the Structure of A Mutant Kcsa K+ Channel


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of A Mutant Kcsa K+ Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:K125 b:56.2 occ:0.25 O C:GLY77 3.1 42.7 1.0 K C:K130 3.4 71.0 0.2 K C:K126 3.6 57.7 0.2 C C:GLY77 3.6 39.8 1.0 CA C:GLY77 4.1 38.0 1.0 N C:TYR78 4.3 41.3 1.0 N C:GLY77 4.4 36.8 1.0 CA C:TYR78 4.6 42.0 1.0 N C:GLY79 4.8 46.5 1.0

Potassium binding site 2 out of 7 in the Structure of A Mutant Kcsa K+ Channel


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of A Mutant Kcsa K+ Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:K126 b:57.7 occ:0.25 K C:K127 2.8 68.0 0.2 N C:GLY77 3.5 36.8 1.0 K C:K125 3.6 56.2 0.2 CA C:VAL76 4.2 35.0 1.0 CA C:GLY77 4.3 38.0 1.0 O C:GLY77 4.3 42.7 1.0 C C:VAL76 4.3 36.4 1.0 O C:THR75 4.4 39.2 1.0 CG1 C:VAL76 4.7 28.9 1.0 C C:GLY77 4.8 39.8 1.0

Potassium binding site 3 out of 7 in the Structure of A Mutant Kcsa K+ Channel


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Structure of A Mutant Kcsa K+ Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:K127 b:68.0 occ:0.25 K C:K126 2.8 57.7 0.2 O C:THR75 2.9 39.2 1.0 K C:K128 3.1 88.3 0.2 C C:THR75 4.0 38.7 1.0 CA C:VAL76 4.2 35.0 1.0 N C:VAL76 4.6 36.1 1.0 OG1 C:THR75 4.8 38.8 1.0 CB C:THR75 4.8 39.9 1.0 CG2 C:VAL76 4.9 30.5 1.0 N C:GLY77 4.9 36.8 1.0

Potassium binding site 4 out of 7 in the Structure of A Mutant Kcsa K+ Channel


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Structure of A Mutant Kcsa K+ Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:K128 b:88.3 occ:0.25 K C:K127 3.1 68.0 0.2 OG1 C:THR75 3.2 38.8 1.0 CB C:THR75 3.9 39.9 1.0 O C:THR75 3.9 39.2 1.0 C C:THR75 4.6 38.7 1.0 O C:THR74 4.7 38.6 1.0 CG2 C:THR75 4.9 39.9 1.0 CA C:THR75 4.9 38.8 1.0

Potassium binding site 5 out of 7 in the Structure of A Mutant Kcsa K+ Channel


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Structure of A Mutant Kcsa K+ Channel within 5.0Å range:

Potassium binding site 6 out of 7 in the Structure of A Mutant Kcsa K+ Channel


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 6 of Structure of A Mutant Kcsa K+ Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:K130 b:71.0 occ:0.25 N C:GLY79 3.1 46.5 1.0 K C:K125 3.4 56.2 0.2 CA C:GLY79 3.5 48.7 1.0 C C:TYR78 4.3 43.7 1.0 O C:GLY79 4.4 52.2 1.0 C C:GLY79 4.5 51.1 1.0 CA C:TYR78 4.6 42.0 1.0 O C:HOH205 4.7 62.4 0.5

Potassium binding site 7 out of 7 in the Structure of A Mutant Kcsa K+ Channel


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 7 of Structure of A Mutant Kcsa K+ Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:K131 b:55.8 occ:0.25 NE2 C:HIS124 2.7 76.3 1.0 CE1 C:HIS124 3.5 77.1 1.0 CD2 C:HIS124 3.8 76.7 1.0 ND1 C:HIS124 4.7 78.0 1.0 CG C:HIS124 4.8 77.1 1.0 NE2 C:GLN119 4.9 82.0 1.0

J.F.Cordero-Morales, L.G.Cuello, Y.Zhao, V.Jogini, D.M.Cortes, B.Roux, E.Perozo. Molecular Determinants of Gating at the Potassium-Channel Selectivity Filter. Nat.Struct.Mol.Biol. V. 13 311 2006.
ISSN: ISSN 1545-9993
PubMed: 16532009
DOI: 10.1038/NSMB1069