Potassium in PDB 1zwi: Structure of Mutant Kcsa Potassium Channel

The structure of Structure of Mutant Kcsa Potassium Channel, PDB code: 1zwi was solved by J.F.Cordero-Morales, L.G.Cuello, Y.Zhao, V.Jogini, D.M.Cortes, B.Roux, E.Perozo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.50
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	155.980, 155.980, 75.960, 90.00, 90.00, 90.00
R / Rfree (%)	24.3 / 25.6

The binding sites of Potassium atom in the Structure of Mutant Kcsa Potassium Channel (pdb code 1zwi). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 7 binding sites of Potassium where determined in the Structure of Mutant Kcsa Potassium Channel, PDB code: 1zwi:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6; 7;

Potassium binding site 1 out of 7 in the Structure of Mutant Kcsa Potassium Channel


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of Mutant Kcsa Potassium Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:K5001 b:68.5 occ:0.25 O C:TYR78 3.2 51.6 1.0 K C:K5002 3.4 59.6 0.2 O C:GLY77 3.5 49.0 1.0 C C:TYR78 3.6 48.9 1.0 N C:GLY79 4.2 49.4 1.0 CA C:TYR78 4.2 48.4 1.0 CA C:GLY79 4.4 49.4 1.0 C C:GLY77 4.5 48.3 1.0 K C:K5007 4.5 0.5 0.3 N C:TYR78 4.8 49.9 1.0

Potassium binding site 2 out of 7 in the Structure of Mutant Kcsa Potassium Channel


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of Mutant Kcsa Potassium Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:K5002 b:59.6 occ:0.25 O C:GLY77 3.2 49.0 1.0 K C:K5003 3.2 58.8 0.2 O C:VAL76 3.2 51.6 1.0 K C:K5001 3.4 68.5 0.2 C C:GLY77 3.8 48.3 1.0 C C:VAL76 4.2 49.2 1.0 CA C:GLY77 4.3 48.4 1.0 N C:TYR78 4.5 49.9 1.0 N C:GLY77 4.7 49.1 1.0 CA C:TYR78 4.9 48.4 1.0

Potassium binding site 3 out of 7 in the Structure of Mutant Kcsa Potassium Channel


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Structure of Mutant Kcsa Potassium Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:K5003 b:58.8 occ:0.25 O C:THR75 3.1 53.5 1.0 K C:K5002 3.2 59.6 0.2 K C:K5004 3.3 59.4 0.2 O C:VAL76 3.4 51.6 1.0 C C:VAL76 3.8 49.2 1.0 CA C:VAL76 4.1 47.9 1.0 C C:THR75 4.2 52.1 1.0 N C:GLY77 4.6 49.1 1.0 N C:VAL76 4.7 51.4 1.0

Potassium binding site 4 out of 7 in the Structure of Mutant Kcsa Potassium Channel


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Structure of Mutant Kcsa Potassium Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:K5004 b:59.4 occ:0.25 OG1 C:THR75 3.3 51.0 1.0 K C:K5003 3.3 58.8 0.2 O C:THR75 3.4 53.5 1.0 CB C:THR75 4.0 52.6 1.0 C C:THR75 4.2 52.1 1.0 CA C:THR75 4.8 52.9 1.0 O C:THR74 5.0 54.5 1.0 N C:VAL76 5.0 51.4 1.0

Potassium binding site 5 out of 7 in the Structure of Mutant Kcsa Potassium Channel


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Structure of Mutant Kcsa Potassium Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:K5005 b:98.6 occ:0.25 O C:HOH5009 3.5 59.3 1.0 O C:HOH5011 3.6 72.9 1.0

Potassium binding site 6 out of 7 in the Structure of Mutant Kcsa Potassium Channel


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 6 of Structure of Mutant Kcsa Potassium Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:K5006 b:0.8 occ:0.25 K C:K5007 3.0 0.5 0.3 O C:HOH5010 3.7 94.4 1.0

Potassium binding site 7 out of 7 in the Structure of Mutant Kcsa Potassium Channel


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 7 of Structure of Mutant Kcsa Potassium Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:K5007 b:0.5 occ:0.25 K C:K5006 3.0 0.8 0.3 O C:TYR78 4.5 51.6 1.0 K C:K5001 4.5 68.5 0.2 O C:HOH5010 4.8 94.4 1.0 O C:GLY79 5.0 49.4 1.0

J.F.Cordero-Morales, L.G.Cuello, Y.Zhao, V.Jogini, D.M.Cortes, B.Roux, E.Perozo. Molecular Determinants of Gating at the Potassium-Channel Selectivity Filter. Nat.Struct.Mol.Biol. V. 13 311 2006.
ISSN: ISSN 1545-9993
PubMed: 16532009
DOI: 10.1038/NSMB1069