Potassium in PDB 1xrc: Crystal Structure of S-Adenosylmethionine Synthetase

All present enzymatic activity of Crystal Structure of S-Adenosylmethionine Synthetase:
2.5.1.6;

The structure of Crystal Structure of S-Adenosylmethionine Synthetase, PDB code: 1xrc was solved by F.Takusagawa, S.Kamitori, S.Misaki, G.D.Markham, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 3.00
Space group	P 62 2 2
Cell size a, b, c (Å), α, β, γ (°)	128.900, 128.900, 139.800, 90.00, 90.00, 120.00
R / Rfree (%)	19.7 / 25.8

The structure of Crystal Structure of S-Adenosylmethionine Synthetase also contains other interesting chemical elements:

Cobalt

(Co)

2 atoms

The binding sites of Potassium atom in the Crystal Structure of S-Adenosylmethionine Synthetase (pdb code 1xrc). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of S-Adenosylmethionine Synthetase, PDB code: 1xrc:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Crystal Structure of S-Adenosylmethionine Synthetase


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of S-Adenosylmethionine Synthetase within 5.0Å range: probe atom residue distance (Å) B Occ A:K413 b:81.5 occ:1.00 O A:SER263 2.5 15.5 1.0 OE1 A:GLU42 2.5 36.6 1.0 CG A:LYS265 3.4 13.9 1.0 CD A:GLU42 3.5 30.6 1.0 HG1 A:THR242 3.5 24.0 0.0 CE A:LYS265 3.6 20.9 1.0 C A:SER263 3.7 17.5 1.0 OE2 A:GLU42 3.7 37.5 1.0 OG1 A:THR242 3.8 12.6 1.0 CD A:LYS265 4.0 15.8 1.0 H A:CYS41 4.3 24.0 0.0 O A:PHE262 4.4 23.2 1.0 C A:GLY264 4.4 20.1 1.0 N A:LYS265 4.5 19.1 1.0 CB A:ALA261 4.5 10.3 1.0 N A:GLY264 4.5 17.9 1.0 CA A:GLY264 4.5 17.8 1.0 H A:LYS265 4.6 24.0 0.0 O A:GLY264 4.6 26.6 1.0 O A:ALA261 4.6 9.3 1.0 C A:PHE262 4.6 17.8 1.0 NZ A:LYS265 4.7 24.4 1.0 N A:SER263 4.7 17.2 1.0 CB A:LYS265 4.7 11.3 1.0 CG A:GLU42 4.7 23.3 1.0 CA A:SER263 4.7 16.6 1.0 HZ3 A:LYS265 4.8 24.0 0.0 HZ1 A:LYS265 4.9 24.0 0.0 C A:ALA261 5.0 10.7 1.0 O A:CYS41 5.0 18.2 1.0

Potassium binding site 2 out of 2 in the Crystal Structure of S-Adenosylmethionine Synthetase


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of S-Adenosylmethionine Synthetase within 5.0Å range: probe atom residue distance (Å) B Occ A:K414 b:57.5 occ:0.50 O A:GLY243 2.6 17.3 1.0 CG2 A:ILE246 3.3 28.5 1.0 C A:GLY243 3.8 15.7 1.0 CB A:ILE246 3.9 17.2 1.0 CD1 A:ILE246 4.0 4.0 1.0 CA A:ARG244 4.2 14.4 1.0 O A:ARG244 4.2 19.1 1.0 CD A:ARG244 4.3 12.1 1.0 CG1 A:ILE246 4.5 5.4 1.0 N A:ARG244 4.5 15.0 1.0 H A:ILE246 4.5 24.0 0.0 C A:ARG244 4.6 18.4 1.0 CG A:ARG244 4.8 6.8 1.0 CA A:GLY243 4.9 14.9 1.0 O A:GLY259 4.9 26.7 1.0 HE A:ARG244 4.9 24.0 0.0

F.Takusagawa, S.Kamitori, S.Misaki, G.D.Markham. Crystal Structure of S-Adenosylmethionine Synthetase. J.Biol.Chem. V. 271 136 1996.
ISSN: ISSN 0021-9258
PubMed: 8550549
DOI: 10.1074/JBC.271.1.136