Potassium in the structure of Crystal Structure of the Human Mitochondrial Branched-Chain Alpha- Ketoacid Dehydrogenase (pdb 1x7w)

The binding sites of Potassium atom in the structure of Crystal Structure of the Human Mitochondrial Branched-Chain Alpha- Ketoacid Dehydrogenase (pdb code 1x7w). This binding sites where shown with 5.0 Angstroms radius around Potassium atom. The 1x7w structure was solved by R.M.WYNN, M.KATO, M.MACHIUS, J.L.CHUANG, J.LI, D.R.TOMCHICK, D.T.CHUANG, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 50.0-1.7 Space group P3121 a (A) 145.672 b (A) 145.672 c (A) 69.236 alpha (°) 90.00 beta (°) 90.00 gamma (°) 120.00 Rfactor (%) 14.7 Rfree (%) 18.1 Potassium Binding Sites: Potassium binding site 1 out of 2 in 1x7w Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Potassium in the PDB 1x7w. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Potassium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Gly111, A: Gln112, A: Ser161, A: Ser162, A: Pro163, A: Leu164, A: Ala165, A: Thr166, A: Gln167, B: Glu113, A: Hoh805, A: Hoh807, A: Hoh814, B: Hoh919, conact list: Atom Atom Distance (A) K O A:Gly111 4.55 K NE2 A:Gln112 4.48 K OE1 A:Gln112 2.91 K CB A:Gln112 4.88 K CD A:Gln112 3.70 K CG A:Gln112 4.46 K O A:Ser161 2.79 K N A:Ser161 4.04 K CB A:Ser161 4.07 K OG A:Ser161 2.89 K C A:Ser161 3.64 K CA A:Ser161 4.13 K O A:Ser162 4.94 K N A:Ser162 4.65 K C A:Ser162 4.54 K O A:Pro163 2.67 K N A:Pro163 4.37 K CD A:Pro163 4.72 K C A:Pro163 3.75 K CA A:Pro163 4.60 K N A:Leu164 4.59 K C A:Leu164 4.65 K CA A:Leu164 4.53 K N A:Ala165 4.48 K N A:Thr166 4.23 K CB A:Thr166 4.41 K OG1 A:Thr166 3.06 K C A:Thr166 4.92 K CA A:Thr166 4.74 K NE2 A:Gln167 4.70 K N A:Gln167 4.20 K OE1 A:Gln167 2.84 K CB A:Gln167 4.48 K CD A:Gln167 3.85 K CG A:Gln167 4.70 K CA A:Gln167 4.98 K OE2 B:Glu113 4.76 K O A:Hoh805 4.64 K O A:Hoh807 2.68 K O A:Hoh814 4.64 K O B:Hoh919 4.18 interactive model: Potassium binding site 2 out of 2 in 1x7w Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Potassium in the PDB 1x7w. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Potassium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: Gly128, B: Ser129, B: Leu130, B: Thr131, B: Cys178, B: Ile179, B: Asp181, B: Lys182, B: Asn183, B: Pro184, B: Cys185, B: Hoh920, B: Hoh1029, conact list: Atom Atom Distance (A) K O B:Gly128 2.67 K C B:Gly128 3.88 K CA B:Gly128 4.91 K O B:Ser129 4.74 K N B:Ser129 4.63 K C B:Ser129 4.27 K CA B:Ser129 4.40 K O B:Leu130 2.88 K N B:Leu130 4.19 K C B:Leu130 3.72 K CA B:Leu130 4.58 K N B:Thr131 4.49 K CB B:Thr131 4.67 K OG1 B:Thr131 3.45 K CA B:Thr131 4.74 K O B:Cys178 2.72 K C B:Cys178 3.92 K CA B:Cys178 4.92 K O B:Ile179 3.93 K N B:Ile179 4.72 K C B:Ile179 4.33 K CA B:Ile179 4.57 K O B:Asp181 2.86 K N B:Asp181 4.32 K CB B:Asp181 4.34 K OD2 B:Asp181 4.95 K C B:Asp181 3.89 K CA B:Asp181 4.45 K N B:Lys182 4.92 K O B:Asn183 2.68 K N B:Asn183 4.16 K C B:Asn183 3.77 K CA B:Asn183 4.68 K N B:Pro184 4.55 K C B:Pro184 4.68 K CA B:Pro184 4.46 K N B:Cys185 4.22 K CB B:Cys185 4.37 K SG B:Cys185 4.00 K CA B:Cys185 4.95 K O B:Hoh920 2.90 K O B:Hoh1029 4.17 interactive model: