Potassium in PDB 1u1d: Structure of E. Coli Uridine Phosphorylase Complexed to 5- (Phenylthio)Acyclouridine (Ptau)

All present enzymatic activity of Structure of E. Coli Uridine Phosphorylase Complexed to 5- (Phenylthio)Acyclouridine (Ptau):
2.4.2.3;

The structure of Structure of E. Coli Uridine Phosphorylase Complexed to 5- (Phenylthio)Acyclouridine (Ptau), PDB code: 1u1d was solved by W.Bu, E.C.Settembre, S.E.Ealick, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.14 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	91.150, 125.746, 140.880, 90.00, 90.00, 90.00
R / Rfree (%)	20.9 / 22.6

The binding sites of Potassium atom in the Structure of E. Coli Uridine Phosphorylase Complexed to 5- (Phenylthio)Acyclouridine (Ptau) (pdb code 1u1d). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Structure of E. Coli Uridine Phosphorylase Complexed to 5- (Phenylthio)Acyclouridine (Ptau), PDB code: 1u1d:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Structure of E. Coli Uridine Phosphorylase Complexed to 5- (Phenylthio)Acyclouridine (Ptau)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of E. Coli Uridine Phosphorylase Complexed to 5- (Phenylthio)Acyclouridine (Ptau) within 5.0Å range: probe atom residue distance (Å) B Occ A:K1001 b:64.8 occ:1.00 O A:ILE69 2.8 15.8 1.0 O B:ILE69 2.8 15.8 1.0 OG A:SER73 2.9 15.8 1.0 OG B:SER73 2.9 15.8 1.0 OE1 B:GLU49 2.9 17.4 1.0 OE1 A:GLU49 3.0 16.4 1.0 O A:HOH3451 3.1 47.1 1.0 CB A:SER73 3.5 15.9 1.0 CB B:SER73 3.5 16.1 1.0 N B:ILE69 3.8 15.7 1.0 N A:ILE69 3.8 16.1 1.0 C B:ILE69 3.8 15.8 1.0 C A:ILE69 3.9 15.9 1.0 CD A:GLU49 4.1 17.0 1.0 CD B:GLU49 4.1 17.5 1.0 C B:GLY68 4.3 15.7 1.0 C A:GLY68 4.3 16.2 1.0 CA B:ILE69 4.3 15.8 1.0 CA A:ILE69 4.4 15.9 1.0 CA A:GLY68 4.4 16.3 1.0 CA B:GLY68 4.4 15.7 1.0 CG A:GLU49 4.5 16.8 1.0 CG B:GLU49 4.5 17.0 1.0 CB B:ILE69 4.7 15.8 1.0 CA A:SER73 4.8 16.0 1.0 CA B:SER73 4.8 16.1 1.0 N A:SER73 4.8 16.0 1.0 O A:THR67 4.9 16.4 1.0 N B:SER73 4.9 16.1 1.0 CB A:ILE69 4.9 15.9 1.0 O B:THR67 4.9 15.6 1.0 N B:GLY70 5.0 15.8 1.0 N A:GLY70 5.0 15.9 1.0

Potassium binding site 2 out of 3 in the Structure of E. Coli Uridine Phosphorylase Complexed to 5- (Phenylthio)Acyclouridine (Ptau)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of E. Coli Uridine Phosphorylase Complexed to 5- (Phenylthio)Acyclouridine (Ptau) within 5.0Å range: probe atom residue distance (Å) B Occ C:K1002 b:56.2 occ:1.00 OG D:SER73 2.8 13.8 1.0 O D:ILE69 2.8 14.5 1.0 O C:ILE69 2.9 15.1 1.0 OE1 D:GLU49 2.9 16.4 1.0 OG C:SER73 2.9 14.3 1.0 OE1 C:GLU49 3.0 17.3 1.0 O D:HOH6444 3.2 37.7 1.0 CB D:SER73 3.5 14.4 1.0 CB C:SER73 3.6 14.5 1.0 N C:ILE69 3.7 15.2 1.0 N D:ILE69 3.8 14.6 1.0 C D:ILE69 3.9 14.6 1.0 C C:ILE69 3.9 15.2 1.0 CD D:GLU49 4.0 16.2 1.0 CD C:GLU49 4.0 16.9 1.0 C C:GLY68 4.3 15.1 1.0 C D:GLY68 4.3 14.7 1.0 CA C:ILE69 4.3 15.0 1.0 CA D:ILE69 4.3 14.6 1.0 CA C:GLY68 4.4 15.2 1.0 CA D:GLY68 4.4 14.8 1.0 CG C:GLU49 4.4 16.2 1.0 CG D:GLU49 4.4 15.8 1.0 CA D:SER73 4.8 14.3 1.0 CB C:ILE69 4.8 15.2 1.0 O D:THR67 4.8 15.1 1.0 O C:THR67 4.8 15.3 1.0 CB D:ILE69 4.8 14.7 1.0 N D:SER73 4.8 14.3 1.0 CA C:SER73 4.9 14.4 1.0 N C:SER73 4.9 14.5 1.0 N D:GLY70 5.0 14.6 1.0

Potassium binding site 3 out of 3 in the Structure of E. Coli Uridine Phosphorylase Complexed to 5- (Phenylthio)Acyclouridine (Ptau)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Structure of E. Coli Uridine Phosphorylase Complexed to 5- (Phenylthio)Acyclouridine (Ptau) within 5.0Å range: probe atom residue distance (Å) B Occ E:K1003 b:74.2 occ:1.00 OG F:SER73 2.8 15.2 1.0 O E:ILE69 2.9 14.9 1.0 O F:ILE69 2.9 15.7 1.0 OG E:SER73 3.0 15.1 1.0 OE1 F:GLU49 3.0 16.4 1.0 OE1 E:GLU49 3.1 16.5 1.0 CB F:SER73 3.7 15.5 1.0 CB E:SER73 3.8 15.4 1.0 N F:ILE69 3.9 15.8 1.0 N E:ILE69 3.9 15.1 1.0 C E:ILE69 3.9 15.0 1.0 C F:ILE69 4.0 15.7 1.0 CD F:GLU49 4.1 16.4 1.0 CD E:GLU49 4.2 16.8 1.0 CA E:ILE69 4.4 15.0 1.0 CA F:ILE69 4.4 15.7 1.0 C F:GLY68 4.4 15.8 1.0 C E:GLY68 4.4 15.3 1.0 CA F:GLY68 4.5 15.8 1.0 CA E:GLY68 4.6 15.4 1.0 CG E:GLU49 4.6 16.8 1.0 CG F:GLU49 4.6 16.3 1.0 CB E:ILE69 4.8 15.0 1.0 CB F:ILE69 4.9 15.7 1.0 N F:SER73 4.9 15.5 1.0 O F:THR67 4.9 15.9 1.0 CA F:SER73 4.9 15.5 1.0 N E:SER73 4.9 15.4 1.0 CA E:SER73 5.0 15.4 1.0

W.Bu, E.C.Settembre, M.H.El Kouni, S.E.Ealick. Structural Basis For Inhibition of Escherichia Coli Uridine Phosphorylase By 5-Substituted Acyclouridines. Acta Crystallogr.,Sect.D V. 61 863 2005.
ISSN: ISSN 0907-4449
PubMed: 15983408
DOI: 10.1107/S0907444905007882