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Potassium in PDB 1t9a: Crystal Structure of Yeast Acetohydroxyacid Synthase in Complex with A Sulfonylurea Herbicide, Tribenuron Methyl

Enzymatic activity of Crystal Structure of Yeast Acetohydroxyacid Synthase in Complex with A Sulfonylurea Herbicide, Tribenuron Methyl

All present enzymatic activity of Crystal Structure of Yeast Acetohydroxyacid Synthase in Complex with A Sulfonylurea Herbicide, Tribenuron Methyl:
2.2.1.6;

Protein crystallography data

The structure of Crystal Structure of Yeast Acetohydroxyacid Synthase in Complex with A Sulfonylurea Herbicide, Tribenuron Methyl, PDB code: 1t9a was solved by J.A.Mccourt, S.S.Pang, L.W.Guddat, R.G.Duggleby, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 2.59
Space group P 4 2 2
Cell size a, b, c (Å), α, β, γ (°) 154.586, 154.586, 178.799, 90.00, 90.00, 90.00
R / Rfree (%) 15.6 / 19.2

Other elements in 1t9a:

The structure of Crystal Structure of Yeast Acetohydroxyacid Synthase in Complex with A Sulfonylurea Herbicide, Tribenuron Methyl also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the Crystal Structure of Yeast Acetohydroxyacid Synthase in Complex with A Sulfonylurea Herbicide, Tribenuron Methyl (pdb code 1t9a). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of Yeast Acetohydroxyacid Synthase in Complex with A Sulfonylurea Herbicide, Tribenuron Methyl, PDB code: 1t9a:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in 1t9a

Go back to Potassium Binding Sites List in 1t9a
Potassium binding site 1 out of 2 in the Crystal Structure of Yeast Acetohydroxyacid Synthase in Complex with A Sulfonylurea Herbicide, Tribenuron Methyl


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Yeast Acetohydroxyacid Synthase in Complex with A Sulfonylurea Herbicide, Tribenuron Methyl within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K1696

b:24.7
occ:1.00
O A:TRP508 2.7 14.4 1.0
OE1 A:GLN343 2.8 23.0 1.0
O A:GLN506 2.8 17.4 1.0
O A:HOH4857 2.8 17.9 1.0
OD2 A:ASP350 2.9 16.6 1.0
O A:HOH4179 3.3 43.1 1.0
CD A:GLN343 3.5 22.0 1.0
NE2 A:GLN343 3.6 19.9 1.0
O A:HOH4497 3.6 50.0 1.0
C A:GLN506 3.8 16.8 1.0
CG A:ASP350 3.8 16.2 1.0
C A:TRP508 3.9 15.2 1.0
OD1 A:ASP350 3.9 15.8 1.0
O A:ALA505 4.0 16.7 1.0
CD1 A:TRP510 4.3 14.0 1.0
N A:TRP508 4.4 16.9 1.0
CA A:THR509 4.5 16.0 1.0
CA A:GLN506 4.5 16.7 1.0
C A:HIS507 4.6 17.3 1.0
N A:HIS507 4.6 17.7 1.0
N A:THR509 4.7 15.0 1.0
NE1 A:TRP510 4.7 14.5 1.0
CA A:HIS507 4.8 17.0 1.0
CE1 A:TYR460 4.8 17.1 1.0
N A:TRP510 4.8 16.2 1.0
CA A:TRP508 4.8 14.9 1.0
O A:HOH4696 4.9 23.5 1.0
CG A:GLN343 4.9 21.5 1.0
C A:ALA505 5.0 14.8 1.0

Potassium binding site 2 out of 2 in 1t9a

Go back to Potassium Binding Sites List in 1t9a
Potassium binding site 2 out of 2 in the Crystal Structure of Yeast Acetohydroxyacid Synthase in Complex with A Sulfonylurea Herbicide, Tribenuron Methyl


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of Yeast Acetohydroxyacid Synthase in Complex with A Sulfonylurea Herbicide, Tribenuron Methyl within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K696

b:40.0
occ:1.00
O B:GLN506 2.6 36.0 1.0
O B:TRP508 2.6 36.6 1.0
O B:HOH4247 2.7 38.0 1.0
OE1 B:GLN343 2.8 38.4 1.0
OD2 B:ASP350 2.8 43.8 1.0
CD B:GLN343 3.4 39.4 1.0
NE2 B:GLN343 3.5 36.1 1.0
C B:GLN506 3.7 34.7 1.0
CG B:ASP350 3.8 44.7 1.0
C B:TRP508 3.8 36.5 1.0
O B:ALA505 3.8 33.0 1.0
OD1 B:ASP350 4.0 45.2 1.0
N B:TRP508 4.2 34.7 1.0
CD1 B:TRP510 4.2 40.0 1.0
CA B:GLN506 4.4 33.9 1.0
NE1 B:TRP510 4.5 39.9 1.0
CA B:THR509 4.5 40.1 1.0
N B:THR509 4.6 38.7 1.0
N B:HIS507 4.6 35.0 1.0
O B:HOH4906 4.7 40.1 1.0
CA B:TRP508 4.7 35.0 1.0
C B:HIS507 4.7 34.6 1.0
CE1 B:TYR460 4.7 51.7 1.0
CG B:GLN343 4.8 41.0 1.0
C B:ALA505 4.8 33.4 1.0
CA B:HIS507 4.9 34.7 1.0
N B:TRP510 4.9 40.4 1.0

Reference:

J.A.Mccourt, S.S.Pang, L.W.Guddat, R.G.Duggleby. Elucidating the Specificity of Binding of Sulfonylurea Herbicides to Acetohydroxyacid Synthase. Biochemistry V. 44 2330 2005.
ISSN: ISSN 0006-2960
PubMed: 15709745
DOI: 10.1021/BI047980A
Page generated: Mon Aug 12 05:27:10 2024

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