Potassium in PDB 1s5h: Potassium Channel Kcsa-Fab Complex T75C Mutant in K+

The structure of Potassium Channel Kcsa-Fab Complex T75C Mutant in K+, PDB code: 1s5h was solved by R.Mackinnon, M.Zhou, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.35 / 2.20
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	154.705, 154.705, 75.927, 90.00, 90.00, 90.00
R / Rfree (%)	22.2 / 24

The binding sites of Potassium atom in the Potassium Channel Kcsa-Fab Complex T75C Mutant in K+ (pdb code 1s5h). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 7 binding sites of Potassium where determined in the Potassium Channel Kcsa-Fab Complex T75C Mutant in K+, PDB code: 1s5h:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6; 7;

Potassium binding site 1 out of 7 in the Potassium Channel Kcsa-Fab Complex T75C Mutant in K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Potassium Channel Kcsa-Fab Complex T75C Mutant in K+ within 5.0Å range: probe atom residue distance (Å) B Occ C:K401 b:22.9 occ:0.25 O C:TYR78 2.9 20.0 1.0 O C:GLY77 3.0 26.1 1.0 K C:K402 3.3 30.4 0.2 C C:TYR78 3.5 22.2 1.0 C C:GLY77 4.1 28.1 1.0 CA C:TYR78 4.1 24.6 1.0 N C:GLY79 4.2 21.8 1.0 K C:K406 4.2 73.6 0.2 CA C:GLY79 4.4 19.2 1.0 N C:TYR78 4.6 25.4 1.0

Potassium binding site 2 out of 7 in the Potassium Channel Kcsa-Fab Complex T75C Mutant in K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Potassium Channel Kcsa-Fab Complex T75C Mutant in K+ within 5.0Å range: probe atom residue distance (Å) B Occ C:K402 b:30.4 occ:0.25 O C:VAL76 2.8 22.4 1.0 O C:GLY77 2.9 26.1 1.0 K C:K401 3.3 22.9 0.2 K C:K403 3.5 22.1 0.2 C C:GLY77 3.6 28.1 1.0 C C:VAL76 4.0 23.7 1.0 CA C:GLY77 4.1 28.2 1.0 N C:TYR78 4.5 25.4 1.0 N C:GLY77 4.5 25.4 1.0 CA C:TYR78 4.9 24.6 1.0

Potassium binding site 3 out of 7 in the Potassium Channel Kcsa-Fab Complex T75C Mutant in K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Potassium Channel Kcsa-Fab Complex T75C Mutant in K+ within 5.0Å range: probe atom residue distance (Å) B Occ C:K403 b:22.1 occ:0.25 O C:CYS75 2.7 23.0 1.0 O C:VAL76 3.2 22.4 1.0 K C:K402 3.5 30.4 0.2 C C:VAL76 3.8 23.7 1.0 C C:CYS75 3.9 23.3 1.0 CA C:VAL76 4.1 22.0 1.0 N C:VAL76 4.5 21.5 1.0 N C:GLY77 4.8 25.4 1.0 CB C:CYS75 5.0 22.1 1.0

Potassium binding site 4 out of 7 in the Potassium Channel Kcsa-Fab Complex T75C Mutant in K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Potassium Channel Kcsa-Fab Complex T75C Mutant in K+ within 5.0Å range: probe atom residue distance (Å) B Occ C:K404 b:75.2 occ:0.25 O C:HOH419 3.5 44.4 1.0 K C:K405 4.1 57.6 0.2 CB C:CYS75 4.3 22.1 1.0 O C:CYS75 4.8 23.0 1.0 O C:THR74 4.9 16.2 1.0

Potassium binding site 5 out of 7 in the Potassium Channel Kcsa-Fab Complex T75C Mutant in K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Potassium Channel Kcsa-Fab Complex T75C Mutant in K+ within 5.0Å range: probe atom residue distance (Å) B Occ C:K405 b:57.6 occ:0.25 O C:HOH419 4.1 44.4 1.0 K C:K404 4.1 75.2 0.2

Potassium binding site 6 out of 7 in the Potassium Channel Kcsa-Fab Complex T75C Mutant in K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 6 of Potassium Channel Kcsa-Fab Complex T75C Mutant in K+ within 5.0Å range: probe atom residue distance (Å) B Occ C:K406 b:73.6 occ:0.25 K C:K407 3.5 58.8 0.2 O C:TYR78 4.0 20.0 1.0 K C:K401 4.2 22.9 0.2 O C:HOH425 4.3 53.6 1.0 CA C:GLY79 4.7 19.2 1.0 O C:GLY79 4.8 23.5 1.0

Potassium binding site 7 out of 7 in the Potassium Channel Kcsa-Fab Complex T75C Mutant in K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 7 of Potassium Channel Kcsa-Fab Complex T75C Mutant in K+ within 5.0Å range: probe atom residue distance (Å) B Occ C:K407 b:58.8 occ:0.25 O C:HOH425 3.3 53.6 1.0 K C:K406 3.5 73.6 0.2

M.Zhou, R.Mackinnon. A Mutant Kcsa K(+) Channel with Altered Conduction Properties and Selectivity Filter Ion Distribution. J.Mol.Biol. V. 338 839 2004.
ISSN: ISSN 0022-2836
PubMed: 15099749
DOI: 10.1016/J.JMB.2004.03.020