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Potassium in PDB 1pl0: Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC
Enzymatic activity of Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC
All present enzymatic activity of Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC:
2.1.2.3; 3.5.4.10;
2.1.2.3; 3.5.4.10;
Protein crystallography data
The structure of Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC, PDB code: 1pl0
was solved by
C.G.Cheong,
S.E.Greasley,
P.A.Horton,
G.P.Beardsley,
I.A.Wilson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 20.00 / 2.60 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 77.120, 92.970, 178.490, 90.00, 91.19, 90.00 |
| R / Rfree (%) | 21.3 / 27.5 |
Potassium Binding Sites:
The binding sites of Potassium atom in the Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC
(pdb code 1pl0). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC, PDB code: 1pl0:
Jump to Potassium binding site number: 1; 2; 3; 4;
In total 4 binding sites of Potassium where determined in the Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC, PDB code: 1pl0:
Jump to Potassium binding site number: 1; 2; 3; 4;
Potassium binding site 1 out of 4 in 1pl0
Go back to
Potassium Binding Sites List in 1pl0
Potassium binding site 1 out
of 4 in the Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 1 of Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC within 5.0Å range:
|
Potassium binding site 2 out of 4 in 1pl0
Go back to
Potassium Binding Sites List in 1pl0
Potassium binding site 2 out
of 4 in the Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 2 of Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC within 5.0Å range:
|
Potassium binding site 3 out of 4 in 1pl0
Go back to
Potassium Binding Sites List in 1pl0
Potassium binding site 3 out
of 4 in the Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 3 of Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC within 5.0Å range:
|
Potassium binding site 4 out of 4 in 1pl0
Go back to
Potassium Binding Sites List in 1pl0
Potassium binding site 4 out
of 4 in the Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 4 of Crystal Structure of Human Atic in Complex with Folate- Based Inhibitor, BW2315U89UC within 5.0Å range:
|
Reference:
C.G.Cheong,
D.W.Wolan,
S.E.Greasley,
P.A.Horton,
G.P.Beardsley,
I.A.Wilson.
Crystal Structures of Human Bifunctional Enzyme Aminoimidazole-4-Carboxamide Ribonucleotide Transformylase/Imp Cyclohydrolase in Complex with Potent Sulfonyl-Containing Antifolates. J.Biol.Chem. V. 279 18034 2004.
ISSN: ISSN 0021-9258
PubMed: 14966129
DOI: 10.1074/JBC.M313691200
Page generated: Mon Aug 12 05:12:23 2024
ISSN: ISSN 0021-9258
PubMed: 14966129
DOI: 10.1074/JBC.M313691200
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