Potassium in PDB 1mxb: S-Adenosylmethionine Synthetase with Adp

All present enzymatic activity of S-Adenosylmethionine Synthetase with Adp:
2.5.1.6;

The structure of S-Adenosylmethionine Synthetase with Adp, PDB code: 1mxb was solved by F.Takusagawa, S.Kamitori, G.D.Markham, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 2.80
Space group	P 62 2 2
Cell size a, b, c (Å), α, β, γ (°)	128.900, 128.900, 139.800, 90.00, 90.00, 120.00
R / Rfree (%)	19.4 / 25.9

The structure of S-Adenosylmethionine Synthetase with Adp also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Potassium atom in the S-Adenosylmethionine Synthetase with Adp (pdb code 1mxb). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the S-Adenosylmethionine Synthetase with Adp, PDB code: 1mxb:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the S-Adenosylmethionine Synthetase with Adp


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of S-Adenosylmethionine Synthetase with Adp within 5.0Å range: probe atom residue distance (Å) B Occ A:K413 b:74.4 occ:1.00 O A:SER263 2.6 10.3 1.0 OE1 A:GLU42 2.7 7.1 1.0 CD A:GLU42 3.0 11.9 1.0 OE2 A:GLU42 3.0 20.7 1.0 HG1 A:THR242 3.5 0.0 0.0 CG A:LYS265 3.7 4.0 1.0 C A:SER263 3.8 5.6 1.0 CE A:LYS265 3.9 7.0 1.0 OG1 A:THR242 3.9 7.7 1.0 CG A:GLU42 4.0 9.6 1.0 O A:CYS41 4.0 17.4 1.0 C A:GLY264 4.2 9.2 1.0 CA A:GLY264 4.3 6.6 1.0 CD A:LYS265 4.3 4.8 1.0 H A:CYS41 4.4 0.0 0.0 O A:GLY264 4.4 11.2 1.0 C A:CYS41 4.5 16.6 1.0 N A:LYS265 4.5 4.0 1.0 N A:GLY264 4.5 5.0 1.0 CA A:GLU42 4.7 4.7 1.0 H A:LYS265 4.7 0.0 0.0 N A:GLU42 4.7 10.8 1.0 N A:CYS41 4.7 12.1 1.0 CB A:GLU42 4.8 6.3 1.0 CB A:ALA261 4.9 4.0 1.0 CB A:LYS265 5.0 4.0 1.0

Potassium binding site 2 out of 2 in the S-Adenosylmethionine Synthetase with Adp


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of S-Adenosylmethionine Synthetase with Adp within 5.0Å range: probe atom residue distance (Å) B Occ A:K414 b:71.4 occ:0.50 O A:GLY243 2.5 10.1 1.0 CG2 A:ILE246 3.4 24.3 1.0 C A:GLY243 3.7 7.7 1.0 CB A:ILE246 4.0 13.6 1.0 CA A:ARG244 4.1 11.2 1.0 CD A:ARG244 4.1 7.1 1.0 CD1 A:ILE246 4.2 5.9 1.0 O A:ARG244 4.3 15.6 1.0 N A:ARG244 4.4 10.0 1.0 H A:ILE246 4.4 0.0 0.0 CG1 A:ILE246 4.5 4.0 1.0 C A:ARG244 4.6 12.7 1.0 O A:GLY259 4.7 26.3 1.0 CA A:GLY243 4.9 4.0 1.0 CG A:ARG244 4.9 4.0 1.0

F.Takusagawa, S.Kamitori, G.D.Markham. Structure and Function of S-Adenosylmethionine Synthetase: Crystal Structures of S-Adenosylmethionine Synthetase with Adp, Bradp, and Ppi at 28 Angstroms Resolution. Biochemistry V. 35 2586 1996.
ISSN: ISSN 0006-2960
PubMed: 8611562
DOI: 10.1021/BI952604Z