Atomistry » Potassium » PDB 1m5h-1o07 » 1m6h
Atomistry »
  Potassium »
    PDB 1m5h-1o07 »
      1m6h »

Potassium in PDB 1m6h: Human Glutathione-Dependent Formaldehyde Dehydrogenase

Enzymatic activity of Human Glutathione-Dependent Formaldehyde Dehydrogenase

All present enzymatic activity of Human Glutathione-Dependent Formaldehyde Dehydrogenase:
1.1.1.1;

Protein crystallography data

The structure of Human Glutathione-Dependent Formaldehyde Dehydrogenase, PDB code: 1m6h was solved by P.C.Sanghani, H.Robinson, W.F.Bosron, T.D.Hurley, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 2.00
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 78.620, 78.620, 309.659, 90.00, 90.00, 90.00
R / Rfree (%) 18.5 / 21.8

Other elements in 1m6h:

The structure of Human Glutathione-Dependent Formaldehyde Dehydrogenase also contains other interesting chemical elements:

Zinc (Zn) 4 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the Human Glutathione-Dependent Formaldehyde Dehydrogenase (pdb code 1m6h). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Human Glutathione-Dependent Formaldehyde Dehydrogenase, PDB code: 1m6h:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in 1m6h

Go back to Potassium Binding Sites List in 1m6h
Potassium binding site 1 out of 2 in the Human Glutathione-Dependent Formaldehyde Dehydrogenase


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human Glutathione-Dependent Formaldehyde Dehydrogenase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K2001

b:18.1
occ:1.00
O A:LYS187 2.8 16.2 1.0
O A:HOH3169 2.8 31.9 1.0
OH A:TYR263 2.8 10.7 1.0
O A:ALA186 2.9 16.4 1.0
OE2 A:GLU189 2.9 16.8 1.0
O A:HOH3246 2.9 20.3 1.0
O A:HOH3090 3.0 32.1 1.0
O A:HOH3331 3.1 46.9 1.0
C A:LYS187 3.6 16.0 1.0
CD A:GLU189 3.6 17.4 1.0
CB A:LYS187 3.8 19.7 1.0
CZ A:TYR263 3.9 12.4 1.0
OE1 A:GLU189 3.9 14.8 1.0
O A:HOH3013 4.0 11.9 1.0
C A:ALA186 4.0 16.0 1.0
O A:HOH3400 4.2 44.5 1.0
CE2 A:TYR263 4.2 13.6 1.0
CA A:LYS187 4.2 17.5 1.0
NZ B:LYS106 4.3 12.1 1.0
N A:LEU188 4.3 16.0 1.0
O B:HOH3030 4.4 16.3 1.0
O A:HOH3005 4.4 31.1 1.0
CA A:LEU188 4.5 18.1 1.0
O A:HOH3116 4.6 21.5 1.0
N A:LYS187 4.6 16.3 1.0
CG A:GLU189 4.7 15.6 1.0

Potassium binding site 2 out of 2 in 1m6h

Go back to Potassium Binding Sites List in 1m6h
Potassium binding site 2 out of 2 in the Human Glutathione-Dependent Formaldehyde Dehydrogenase


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Human Glutathione-Dependent Formaldehyde Dehydrogenase within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K2002

b:20.3
occ:1.00
O B:LYS187 2.8 18.7 1.0
OH B:TYR263 2.8 15.3 1.0
OE2 B:GLU189 2.9 18.4 1.0
O A:HOH3354 2.9 27.2 1.0
O B:ALA186 2.9 18.3 1.0
O B:HOH3315 2.9 33.3 1.0
O B:HOH3279 3.0 22.6 1.0
C B:LYS187 3.5 18.6 1.0
CD B:GLU189 3.7 19.3 1.0
CB B:LYS187 3.8 21.7 1.0
CZ B:TYR263 3.9 14.5 1.0
O B:HOH3041 4.0 17.1 1.0
C B:ALA186 4.1 18.3 1.0
OE1 B:GLU189 4.1 16.7 1.0
NZ A:LYS106 4.1 16.0 1.0
CA B:LYS187 4.2 18.9 1.0
CE2 B:TYR263 4.2 14.8 1.0
N B:LEU188 4.4 17.5 1.0
O A:HOH3020 4.4 15.2 1.0
O B:HOH3132 4.4 25.3 1.0
O A:HOH3239 4.4 42.2 1.0
CA B:LEU188 4.6 18.5 1.0
N B:LYS187 4.6 16.4 1.0
CG B:GLU189 4.8 18.9 1.0

Reference:

P.C.Sanghani, H.Robinson, W.F.Bosron, T.D.Hurley. Human Glutathione-Dependent Formaldehyde Dehydrogenase. Structures of Apo, Binary, and Inhibitory Ternary Complexes. Biochemistry V. 41 10778 2002.
ISSN: ISSN 0006-2960
PubMed: 12196016
DOI: 10.1021/BI0257639
Page generated: Sun Dec 13 22:51:46 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy