Potassium in PDB 1lqk: High Resolution Structure of Fosfomycin Resistance Protein A (Fosa)

All present enzymatic activity of High Resolution Structure of Fosfomycin Resistance Protein A (Fosa):
2.5.1.18;

The structure of High Resolution Structure of Fosfomycin Resistance Protein A (Fosa), PDB code: 1lqk was solved by C.L.Rife, R.E.Pharris, M.E.Newcomer, R.N.Armstrong, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.35
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	54.788, 66.967, 77.000, 90.00, 90.00, 90.00
R / Rfree (%)	14.3 / 18.5

The structure of High Resolution Structure of Fosfomycin Resistance Protein A (Fosa) also contains other interesting chemical elements:

Manganese

(Mn)

2 atoms

The binding sites of Potassium atom in the High Resolution Structure of Fosfomycin Resistance Protein A (Fosa) (pdb code 1lqk). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the High Resolution Structure of Fosfomycin Resistance Protein A (Fosa), PDB code: 1lqk:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the High Resolution Structure of Fosfomycin Resistance Protein A (Fosa)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of High Resolution Structure of Fosfomycin Resistance Protein A (Fosa) within 5.0Å range: probe atom residue distance (Å) B Occ A:K701 b:15.6 occ:1.00 OD1 A:ASN92 2.6 20.9 1.0 OG A:SER94 2.7 18.4 1.0 O A:GLY96 2.7 15.7 1.0 OG A:SER98 2.8 11.3 1.0 O A:GLU95 3.0 13.7 1.0 O A:SER94 3.2 17.9 1.0 CB A:SER98 3.5 11.1 1.0 C A:SER94 3.6 17.6 1.0 CG A:ASN92 3.6 18.6 1.0 OH A:TYR100 3.6 14.8 1.0 NH2 A:ARG119 3.7 17.6 1.0 O2 A:PO4501 3.7 13.9 0.6 NE2 A:HIS112 3.7 12.4 1.0 C A:GLU95 3.7 15.0 1.0 CD2 A:HIS112 3.8 8.2 1.0 CB A:SER94 3.8 19.0 1.0 ND2 A:ASN92 3.9 21.7 1.0 C A:GLY96 3.9 15.0 1.0 CA A:SER94 4.0 18.7 1.0 N A:SER94 4.2 19.7 1.0 O2 A:PO4501 4.2 19.2 0.3 N A:GLU95 4.2 16.6 1.0 N A:GLY96 4.3 14.2 1.0 N A:SER98 4.4 10.4 1.0 O A:HOH1031 4.4 18.9 1.0 OE2 A:GLU110 4.4 10.0 1.0 CA A:GLY96 4.5 14.9 1.0 C A:ASP97 4.5 10.6 1.0 CA A:SER98 4.5 9.1 1.0 CA A:GLU95 4.6 15.4 1.0 O A:ASP97 4.6 10.1 1.0 P A:PO4501 4.7 13.8 0.6 CZ A:TYR100 4.7 11.4 1.0 O1 A:PO4501 4.8 15.6 0.6 CZ A:ARG119 4.8 15.9 1.0 CE1 A:HIS112 4.9 8.9 1.0 O4 A:PO4501 4.9 15.9 0.6 N A:ASP97 4.9 13.5 1.0 CB A:ASN92 4.9 16.7 1.0 CG A:HIS112 5.0 9.1 1.0

Potassium binding site 2 out of 2 in the High Resolution Structure of Fosfomycin Resistance Protein A (Fosa)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of High Resolution Structure of Fosfomycin Resistance Protein A (Fosa) within 5.0Å range: probe atom residue distance (Å) B Occ B:K601 b:13.5 occ:0.85 OG B:SER94 2.6 17.4 1.0 OD1 B:ASN92 2.7 21.3 1.0 O B:GLY96 2.8 14.2 1.0 OG B:SER98 2.8 10.8 1.0 O B:GLU95 3.0 12.8 1.0 O B:SER94 3.0 17.2 1.0 CB B:SER98 3.5 10.0 1.0 C B:SER94 3.5 16.9 1.0 NH2 B:ARG119 3.5 14.7 1.0 OH B:TYR100 3.6 13.2 1.0 CG B:ASN92 3.6 21.0 1.0 O4 B:PO4401 3.7 12.1 0.6 CB B:SER94 3.7 18.7 1.0 C B:GLU95 3.7 13.4 1.0 CE1 B:HIS112 3.8 9.2 1.0 ND2 B:ASN92 3.9 25.4 1.0 ND1 B:HIS112 3.9 9.9 1.0 C B:GLY96 3.9 14.1 1.0 CA B:SER94 4.0 19.1 1.0 N B:SER94 4.1 20.0 1.0 N B:GLU95 4.2 15.1 1.0 O4 B:PO4401 4.2 15.7 0.3 N B:SER98 4.3 11.2 1.0 O B:HOH860 4.4 19.5 1.0 N B:GLY96 4.4 13.9 1.0 OE2 B:GLU110 4.5 10.3 1.0 CA B:SER98 4.5 10.3 1.0 CA B:GLY96 4.5 13.9 1.0 C B:ASP97 4.5 12.3 1.0 CA B:GLU95 4.6 13.6 1.0 CZ B:TYR100 4.6 11.5 1.0 P B:PO4401 4.7 13.2 0.6 CZ B:ARG119 4.7 11.6 1.0 O B:ASP97 4.7 11.8 1.0 O2 B:PO4401 4.8 13.4 0.6 O1 B:PO4401 4.9 11.1 0.6 NE2 B:HIS112 4.9 9.9 1.0 CB B:ASN92 5.0 19.1 1.0 N B:ASP97 5.0 13.1 1.0

C.L.Rife, R.E.Pharris, M.E.Newcomer, R.N.Armstrong. Crystal Structure of A Genomically Encoded Fosfomycin Resistance Protein (Fosa) at 1.19 A Resolution By Mad Phasing Off the L-III Edge of Tl(+) J.Am.Chem.Soc. V. 124 11001 2002.
ISSN: ISSN 0002-7863
PubMed: 12224946
DOI: 10.1021/JA026879V