Potassium in PDB 1k73: Co-Crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit

The structure of Co-Crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit, PDB code: 1k73 was solved by J.Hansen, N.Ban, P.Nissen, P.B.Moore, T.A.Steitz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 3.01
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	213.245, 300.750, 574.806, 90.00, 90.00, 90.00
R / Rfree (%)	21.2 / 24.6

The structure of Co-Crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit also contains other interesting chemical elements:

Magnesium	(Mg)	117 atoms
Cadmium	(Cd)	5 atoms
Chlorine	(Cl)	22 atoms
Sodium	(Na)	86 atoms

The binding sites of Potassium atom in the Co-Crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit (pdb code 1k73). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Co-Crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit, PDB code: 1k73:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Co-Crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Co-Crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit within 5.0Å range: probe atom residue distance (Å) B Occ A:K8200 b:66.6 occ:1.00 O6 A:G2482 2.6 29.9 1.0 N7 A:G2482 2.8 32.3 1.0 O6 A:G2102 2.8 41.1 1.0 O2 A:C2536 2.9 31.3 1.0 O4' A:C2536 3.1 31.2 1.0 C6 A:G2482 3.2 29.4 1.0 O4 A:ANM9000 3.2 33.5 1.0 C5 A:G2482 3.3 30.5 1.0 N7 A:G2102 3.5 40.3 1.0 C2 A:C2536 3.5 31.9 1.0 C1' A:C2536 3.6 31.3 1.0 C6 A:G2102 3.6 41.0 1.0 N1 A:C2536 3.8 31.5 1.0 C5 A:G2102 3.8 41.2 1.0 N6 A:A2486 3.9 40.3 1.0 C8 A:G2482 4.0 30.6 1.0 C4' A:C2536 4.1 30.5 1.0 C3 A:ANM9000 4.1 33.9 1.0 C2 A:ANM9000 4.3 33.6 1.0 N3 A:C2536 4.4 31.6 1.0 O2 A:U2535 4.4 33.3 1.0 C2 A:U2535 4.5 32.6 1.0 N1 A:G2482 4.5 28.2 1.0 C4 A:G2482 4.6 30.4 1.0 C5' A:C2536 4.6 30.5 1.0 C8 A:G2102 4.7 40.9 1.0 N3 A:U2535 4.7 30.6 1.0 C2' A:U2535 4.7 33.4 1.0 C6 A:C2536 4.8 32.0 1.0 N1 A:G2102 4.8 41.7 1.0 OP1 A:U2539 4.9 26.8 1.0 N9 A:G2482 5.0 29.9 1.0

Potassium binding site 2 out of 2 in the Co-Crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Co-Crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit within 5.0Å range: probe atom residue distance (Å) B Occ A:K8201 b:69.8 occ:1.00 O A:HOH9014 2.7 31.4 1.0 O A:HOH9112 2.7 37.6 1.0 O4 A:U163 3.0 31.2 1.0 O4 A:U172 3.1 31.2 1.0 O A:HOH4924 3.1 40.0 1.0 O A:HOH9147 3.2 23.5 1.0 O A:HOH7834 3.3 44.4 1.0 OP2 A:C162 3.4 20.8 1.0 CD N:ARG82 3.6 33.6 1.0 C4 A:U172 4.0 32.2 1.0 O A:HOH9323 4.0 32.9 1.0 O A:HOH7833 4.0 18.9 1.0 N3 A:U172 4.0 32.2 1.0 C4 A:U163 4.1 32.9 1.0 N4 A:C171 4.2 35.5 1.0 OP2 A:A169 4.4 28.5 1.0 NE N:ARG82 4.4 35.2 1.0 O6 A:G164 4.5 31.0 1.0 C5 A:U163 4.5 33.5 1.0 P A:C162 4.6 23.8 1.0 OP1 A:A169 4.6 29.1 1.0 CB N:ARG82 4.7 31.4 1.0 CG N:ARG82 4.7 32.6 1.0 MG A:MG8054 4.8 40.1 1.0 OP1 A:C162 4.9 22.3 1.0 P A:A169 4.9 28.1 1.0 N4 A:C173 4.9 31.5 1.0

J.Hansen, P.B.Moore, T.A.Steitz. Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit J.Mol.Biol. V. 330 1061 2003.
ISSN: ISSN 0022-2836
PubMed: 12860128
DOI: 10.1016/S0022-2836(03)00668-5