Potassium in PDB 1j95: Kcsa Potassium Channel with Tba (Tetrabutylammonium) and Potassium

The structure of Kcsa Potassium Channel with Tba (Tetrabutylammonium) and Potassium, PDB code: 1j95 was solved by J.H.Morais-Cabral, R.Mackinnon, M.Zhou, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.80
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	128.900, 67.400, 112.000, 90.00, 125.30, 90.00
R / Rfree (%)	29.8 / 32.2

The binding sites of Potassium atom in the Kcsa Potassium Channel with Tba (Tetrabutylammonium) and Potassium (pdb code 1j95). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Kcsa Potassium Channel with Tba (Tetrabutylammonium) and Potassium, PDB code: 1j95:
Jump to Potassium binding site number: 1; 2; 3; 4;

Potassium binding site 1 out of 4 in the Kcsa Potassium Channel with Tba (Tetrabutylammonium) and Potassium


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Kcsa Potassium Channel with Tba (Tetrabutylammonium) and Potassium within 5.0Å range: probe atom residue distance (Å) B Occ A:K201 b:53.3 occ:1.00 O B:GLY77 2.9 90.2 1.0 O C:GLY77 2.9 84.4 1.0 O B:TYR78 2.9 56.9 1.0 K A:K202 2.9 75.8 1.0 O A:GLY77 3.0 86.5 1.0 O C:TYR78 3.1 65.1 1.0 O A:TYR78 3.1 68.0 1.0 O D:GLY77 3.1 91.3 1.0 O D:TYR78 3.1 50.4 1.0 C B:TYR78 3.2 63.5 1.0 C C:TYR78 3.3 69.4 1.0 C A:TYR78 3.4 72.2 1.0 C D:TYR78 3.5 64.8 1.0 CA B:TYR78 3.6 66.6 1.0 CA A:TYR78 3.7 71.5 1.0 CA C:TYR78 3.8 68.9 1.0 CA D:TYR78 3.8 67.8 1.0 C B:GLY77 3.9 76.4 1.0 C C:GLY77 3.9 77.6 1.0 N B:GLY79 4.0 65.9 1.0 C A:GLY77 4.0 83.4 1.0 N C:GLY79 4.0 75.2 1.0 C D:GLY77 4.1 78.0 1.0 N A:GLY79 4.1 76.0 1.0 N D:GLY79 4.2 74.5 1.0 N B:TYR78 4.2 69.5 1.0 N A:TYR78 4.3 79.4 1.0 N C:TYR78 4.3 76.0 1.0 CA B:GLY79 4.4 72.1 1.0 N D:TYR78 4.5 75.1 1.0 CA C:GLY79 4.5 78.0 1.0 CA A:GLY79 4.6 80.1 1.0 CA D:GLY79 4.6 75.0 1.0 CB B:TYR78 4.9 72.2 1.0 O A:VAL76 4.9 76.5 1.0 O B:VAL76 4.9 74.5 1.0 CB A:TYR78 5.0 63.7 1.0 O C:VAL76 5.0 66.2 1.0

Potassium binding site 2 out of 4 in the Kcsa Potassium Channel with Tba (Tetrabutylammonium) and Potassium


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Kcsa Potassium Channel with Tba (Tetrabutylammonium) and Potassium within 5.0Å range: probe atom residue distance (Å) B Occ A:K202 b:75.8 occ:1.00 O A:VAL76 2.6 76.5 1.0 O C:VAL76 2.6 66.2 1.0 O B:VAL76 2.6 74.5 1.0 O D:VAL76 2.7 66.2 1.0 O B:GLY77 2.8 90.2 1.0 O C:GLY77 2.8 84.4 1.0 O A:GLY77 2.8 86.5 1.0 O D:GLY77 2.8 91.3 1.0 K A:K201 2.9 53.3 1.0 K A:K203 3.3 80.0 1.0 C B:GLY77 3.5 76.4 1.0 C C:GLY77 3.5 77.6 1.0 C A:GLY77 3.5 83.4 1.0 C D:GLY77 3.6 78.0 1.0 C A:VAL76 3.8 76.0 1.0 C C:VAL76 3.8 65.3 1.0 C B:VAL76 3.8 72.8 1.0 C D:VAL76 3.9 69.2 1.0 CA B:GLY77 4.2 73.5 1.0 CA C:GLY77 4.2 70.4 1.0 CA A:GLY77 4.2 83.7 1.0 CA D:GLY77 4.2 73.7 1.0 N A:TYR78 4.3 79.4 1.0 N B:TYR78 4.3 69.5 1.0 N C:TYR78 4.3 76.0 1.0 N D:TYR78 4.3 75.1 1.0 N A:GLY77 4.5 82.6 1.0 N B:GLY77 4.5 74.2 1.0 N C:GLY77 4.5 70.6 1.0 CA B:TYR78 4.5 66.6 1.0 CA D:TYR78 4.5 67.8 1.0 CA A:TYR78 4.5 71.5 1.0 N D:GLY77 4.5 72.4 1.0 CA C:TYR78 4.5 68.9 1.0 C B:TYR78 4.9 63.5 1.0 C D:TYR78 4.9 64.8 1.0 C C:TYR78 4.9 69.4 1.0 C A:TYR78 4.9 72.2 1.0 CA A:VAL76 4.9 74.8 1.0 CA C:VAL76 5.0 59.7 1.0

Potassium binding site 3 out of 4 in the Kcsa Potassium Channel with Tba (Tetrabutylammonium) and Potassium


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Kcsa Potassium Channel with Tba (Tetrabutylammonium) and Potassium within 5.0Å range: probe atom residue distance (Å) B Occ A:K203 b:80.0 occ:1.00 O A:THR75 2.5 90.3 1.0 O A:VAL76 2.6 76.5 1.0 O B:THR75 2.6 86.3 1.0 O B:VAL76 2.7 74.5 1.0 O D:THR75 2.7 94.5 1.0 O D:VAL76 2.8 66.2 1.0 O C:THR75 2.8 0.0 1.0 O C:VAL76 2.9 66.2 1.0 C A:VAL76 3.2 76.0 1.0 K A:K202 3.3 75.8 1.0 C B:VAL76 3.4 72.8 1.0 CA A:VAL76 3.5 74.8 1.0 C D:VAL76 3.5 69.2 1.0 K B:K204 3.5 64.1 1.0 C A:THR75 3.5 88.2 1.0 C B:THR75 3.6 83.6 1.0 C C:VAL76 3.6 65.3 1.0 CA D:VAL76 3.7 70.7 1.0 CA B:VAL76 3.7 70.4 1.0 C D:THR75 3.8 89.8 1.0 C C:THR75 3.8 90.6 1.0 CA C:VAL76 3.9 59.7 1.0 N A:VAL76 3.9 83.4 1.0 N B:VAL76 4.1 78.8 1.0 N D:VAL76 4.2 82.4 1.0 N C:VAL76 4.3 77.8 1.0 N A:GLY77 4.4 82.6 1.0 N B:GLY77 4.5 74.2 1.0 N D:GLY77 4.6 72.4 1.0 N C:GLY77 4.7 70.6 1.0 CA A:THR75 4.8 88.5 1.0 CA B:THR75 4.8 82.0 1.0 CB A:VAL76 4.9 63.6 1.0

Potassium binding site 4 out of 4 in the Kcsa Potassium Channel with Tba (Tetrabutylammonium) and Potassium


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Kcsa Potassium Channel with Tba (Tetrabutylammonium) and Potassium within 5.0Å range: probe atom residue distance (Å) B Occ B:K204 b:64.1 occ:1.00 O B:THR75 2.6 86.3 1.0 O C:THR75 2.7 0.0 1.0 O D:THR75 2.8 94.5 1.0 O A:THR75 2.8 90.3 1.0 OG1 C:THR75 2.9 86.3 1.0 OG1 B:THR75 2.9 86.8 1.0 OG1 A:THR75 3.0 84.0 1.0 OG1 D:THR75 3.1 91.5 1.0 CB C:THR75 3.3 83.8 1.0 CB B:THR75 3.4 80.3 1.0 K A:K203 3.5 80.0 1.0 CB D:THR75 3.5 87.8 1.0 CB A:THR75 3.5 86.3 1.0 C B:THR75 3.6 83.6 1.0 C C:THR75 3.6 90.6 1.0 C A:THR75 3.7 88.2 1.0 C D:THR75 3.8 89.8 1.0 CA C:THR75 4.1 87.9 1.0 CA B:THR75 4.2 82.0 1.0 CA A:THR75 4.3 88.5 1.0 CA D:THR75 4.3 89.7 1.0 O B:THR74 4.5 77.3 1.0 O C:THR74 4.6 81.0 1.0 CG2 C:THR75 4.6 83.7 1.0 O A:THR74 4.6 81.2 1.0 N B:VAL76 4.6 78.8 1.0 CG2 B:THR75 4.7 79.5 1.0 N C:VAL76 4.7 77.8 1.0 O D:THR74 4.7 83.2 1.0 N A:VAL76 4.7 83.4 1.0 CG2 D:THR75 4.8 94.9 1.0 C11 A:TBA204 4.8 53.2 1.0 C21 A:TBA204 4.8 56.5 1.0 CG2 A:THR75 4.8 86.4 1.0 N D:VAL76 4.8 82.4 1.0 C31 A:TBA204 4.9 74.5 1.0 CA B:VAL76 4.9 70.4 1.0 N1 A:TBA204 4.9 71.9 1.0 CA C:VAL76 5.0 59.7 1.0

M.Zhou, J.H.Morais-Cabral, S.Mann, R.Mackinnon. Potassium Channel Receptor Site For the Inactivation Gate and Quaternary Amine Inhibitors Nature V. 411 657 2001.
ISSN: ISSN 0028-0836
PubMed: 11395760
DOI: 10.1038/35079500