Potassium in PDB 1ad1: Dihydropteroate Synthetase (Apo Form) From Staphylococcus Aureus

All present enzymatic activity of Dihydropteroate Synthetase (Apo Form) From Staphylococcus Aureus:
2.5.1.15;

The structure of Dihydropteroate Synthetase (Apo Form) From Staphylococcus Aureus, PDB code: 1ad1 was solved by D.Kostrewa, C.Oefner, A.D'arcy, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	13.50 / 2.20
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	64.470, 42.190, 101.320, 90.00, 106.33, 90.00
R / Rfree (%)	15.9 / 21.8

The binding sites of Potassium atom in the Dihydropteroate Synthetase (Apo Form) From Staphylococcus Aureus (pdb code 1ad1). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Dihydropteroate Synthetase (Apo Form) From Staphylococcus Aureus, PDB code: 1ad1:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Dihydropteroate Synthetase (Apo Form) From Staphylococcus Aureus


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Dihydropteroate Synthetase (Apo Form) From Staphylococcus Aureus within 5.0Å range: probe atom residue distance (Å) B Occ A:K268 b:26.6 occ:1.00 O A:VAL79 2.7 15.6 1.0 O A:PHE77 2.7 20.5 1.0 O A:VAL75 2.8 22.5 1.0 O A:HOH517 2.9 13.2 1.0 O A:HOH589 3.1 25.9 1.0 O A:HOH594 3.2 27.0 1.0 C A:VAL75 3.8 20.8 1.0 C A:VAL79 3.8 13.3 1.0 C A:PHE77 3.9 18.5 1.0 O A:HOH656 4.0 35.3 1.0 N A:VAL79 4.1 16.5 1.0 CG1 A:ILE81 4.4 8.3 1.0 OD2 A:ASP100 4.4 11.9 1.0 CA A:VAL75 4.4 19.8 1.0 N A:PHE77 4.5 19.1 1.0 C A:GLY76 4.6 19.4 1.0 CA A:VAL79 4.7 14.8 1.0 CA A:LYS80 4.7 12.6 1.0 N A:GLY76 4.7 22.0 1.0 N A:LYS80 4.7 12.8 1.0 O A:ILE74 4.7 20.8 1.0 CG2 A:VAL75 4.8 22.9 1.0 CA A:PHE77 4.8 17.3 1.0 N A:ASP78 4.9 17.6 1.0 CA A:GLY76 4.9 21.5 1.0 CA A:ASP78 4.9 18.8 1.0 O A:GLY76 4.9 20.3 1.0 CG1 A:VAL79 5.0 7.4 1.0

Potassium binding site 2 out of 2 in the Dihydropteroate Synthetase (Apo Form) From Staphylococcus Aureus


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Dihydropteroate Synthetase (Apo Form) From Staphylococcus Aureus within 5.0Å range: probe atom residue distance (Å) B Occ B:K1 b:20.8 occ:1.00 O B:VAL79 2.6 15.6 1.0 O B:PHE77 2.7 19.1 1.0 O B:HOH291 2.7 15.1 1.0 O B:VAL75 2.8 17.7 1.0 O B:HOH424 3.4 33.1 1.0 C B:VAL79 3.7 17.1 1.0 C B:VAL75 3.8 16.1 1.0 C B:PHE77 3.9 18.8 1.0 N B:VAL79 3.9 15.3 1.0 O B:HOH444 4.0 36.9 1.0 CG1 B:ILE81 4.3 11.5 1.0 OD2 B:ASP100 4.3 15.8 1.0 N B:PHE77 4.3 14.6 1.0 CA B:VAL75 4.5 15.3 1.0 CA B:VAL79 4.5 13.7 1.0 C B:GLY76 4.6 14.6 1.0 N B:LYS80 4.6 14.8 1.0 CA B:LYS80 4.7 14.9 1.0 N B:GLY76 4.7 15.7 1.0 CA B:PHE77 4.7 15.9 1.0 CG2 B:VAL75 4.8 13.9 1.0 CA B:GLY76 4.8 12.0 1.0 O B:ILE74 4.8 16.8 1.0 CD1 B:ILE81 4.9 11.5 1.0 N B:ASP78 4.9 21.4 1.0 C B:ASP78 5.0 19.2 1.0 N B:ILE81 5.0 14.3 1.0 CA B:ASP78 5.0 21.3 1.0 CG1 B:VAL79 5.0 4.9 1.0

I.C.Hampele, A.D'arcy, G.E.Dale, D.Kostrewa, J.Nielsen, C.Oefner, M.G.Page, H.J.Schonfeld, D.Stuber, R.L.Then. Structure and Function of the Dihydropteroate Synthase From Staphylococcus Aureus. J.Mol.Biol. V. 268 21 1997.
ISSN: ISSN 0022-2836
PubMed: 9149138
DOI: 10.1006/JMBI.1997.0944