Potassium in PDB 8s3e: Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26

The structure of Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26 also contains other interesting chemical elements:

Calcium	(Ca)	8 atoms
Magnesium	(Mg)	4 atoms

The binding sites of Potassium atom in the Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26 (pdb code 8s3e). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26, PDB code: 8s3e:
Jump to Potassium binding site number: 1; 2; 3; 4;

Potassium binding site 1 out of 4 in the Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26 within 5.0Å range: probe atom residue distance (Å) B Occ A:K1217 b:30.0 occ:1.00 O D:VAL288 2.9 33.4 1.0 O A:VAL288 3.0 33.4 1.0 O C:VAL288 3.0 33.4 1.0 O B:VAL288 3.1 33.4 1.0 O D:GLY289 3.2 46.3 1.0 K A:K1218 3.3 30.0 1.0 O C:GLY289 3.3 46.3 1.0 O A:GLY289 3.3 46.3 1.0 O B:GLY289 3.4 46.3 1.0 K D:K1217 3.5 30.0 1.0 C D:GLY289 3.5 22.6 1.0 CA D:GLY289 3.6 12.2 1.0 C A:GLY289 3.6 22.6 1.0 C C:GLY289 3.7 22.6 1.0 CA A:GLY289 3.7 12.2 1.0 C B:GLY289 3.7 22.6 1.0 CA B:GLY289 3.7 12.2 1.0 CA C:GLY289 3.8 12.2 1.0 C D:VAL288 4.0 13.0 1.0 C A:VAL288 4.0 13.0 1.0 C C:VAL288 4.1 13.0 1.0 C B:VAL288 4.1 13.0 1.0 N D:GLY289 4.3 13.5 1.0 N A:GLY289 4.3 13.5 1.0 N B:GLY289 4.4 13.5 1.0 N D:TYR290 4.4 26.0 1.0 N C:GLY289 4.4 13.5 1.0 N A:TYR290 4.5 26.0 1.0 N C:TYR290 4.6 26.0 1.0 N B:TYR290 4.6 26.0 1.0

Potassium binding site 2 out of 4 in the Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26 within 5.0Å range: probe atom residue distance (Å) B Occ A:K1218 b:30.0 occ:1.00 K A:K1217 3.3 30.0 1.0 O D:TYR290 3.3 40.4 1.0 O C:TYR290 3.4 40.4 1.0 O A:TYR290 3.4 40.4 1.0 O B:TYR290 3.5 40.4 1.0 C D:TYR290 3.6 31.1 1.0 C A:TYR290 3.7 31.1 1.0 C C:TYR290 3.7 31.1 1.0 C B:TYR290 3.8 31.1 1.0 CA D:TYR290 4.0 25.9 1.0 CA A:TYR290 4.1 25.9 1.0 O D:GLY289 4.1 46.3 1.0 O A:GLY289 4.1 46.3 1.0 CA C:TYR290 4.1 25.9 1.0 CA B:TYR290 4.2 25.9 1.0 O C:GLY289 4.2 46.3 1.0 N D:TYR290 4.2 26.0 1.0 C D:GLY289 4.2 22.6 1.0 N D:GLY291 4.2 27.4 1.0 O B:GLY289 4.2 46.3 1.0 C A:GLY289 4.2 22.6 1.0 N A:TYR290 4.3 26.0 1.0 C B:GLY289 4.3 22.6 1.0 N B:TYR290 4.3 26.0 1.0 N B:GLY291 4.3 27.4 1.0 N A:GLY291 4.4 27.4 1.0 C C:GLY289 4.4 22.6 1.0 N C:TYR290 4.4 26.0 1.0 N C:GLY291 4.4 27.4 1.0 O C:HOH1301 4.7 30.0 1.0 CA D:GLY291 4.8 27.6 1.0 O D:HOH1301 4.8 30.0 1.0 CA B:GLY291 4.8 27.6 1.0 CA A:GLY291 4.9 27.6 1.0 O A:HOH1301 4.9 30.0 1.0 O B:HOH1301 4.9 30.0 1.0 CA C:GLY291 4.9 27.6 1.0

Potassium binding site 3 out of 4 in the Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26 within 5.0Å range: probe atom residue distance (Å) B Occ B:K1217 b:30.0 occ:1.00 O D:THR287 2.7 37.9 1.0 O B:THR287 2.7 37.9 1.0 O A:THR287 2.7 37.9 1.0 O C:THR287 2.7 37.9 1.0 OG1 B:THR287 3.1 30.1 1.0 OG1 A:THR287 3.1 30.1 1.0 OG1 D:THR287 3.1 30.1 1.0 K D:K1217 3.2 30.0 1.0 OG1 C:THR287 3.3 30.1 1.0 CB B:THR287 3.4 21.1 1.0 CB A:THR287 3.5 21.1 1.0 CB D:THR287 3.6 21.1 1.0 O D:HOH1304 3.6 30.0 1.0 CB C:THR287 3.7 21.1 1.0 C D:THR287 3.7 15.0 1.0 C B:THR287 3.7 15.0 1.0 C A:THR287 3.8 15.0 1.0 C C:THR287 3.8 15.0 1.0 CA B:THR287 4.2 17.8 1.0 CA D:THR287 4.3 17.8 1.0 CA A:THR287 4.3 17.8 1.0 CA C:THR287 4.4 17.8 1.0 CG2 B:THR287 4.7 21.0 1.0 N D:VAL288 4.7 19.4 1.0 CG2 A:THR287 4.8 21.0 1.0 N B:VAL288 4.8 19.4 1.0 N C:VAL288 4.8 19.4 1.0 N A:VAL288 4.8 19.4 1.0 CG2 D:THR287 4.8 21.0 1.0 CG2 C:THR287 5.0 21.0 1.0 CA D:VAL288 5.0 15.9 1.0 CA C:VAL288 5.0 15.9 1.0

Potassium binding site 4 out of 4 in the Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26 within 5.0Å range: probe atom residue distance (Å) B Occ D:K1217 b:30.0 occ:1.00 O D:VAL288 2.6 33.4 1.0 O A:THR287 2.6 37.9 1.0 O C:VAL288 2.6 33.4 1.0 O B:THR287 2.6 37.9 1.0 O D:THR287 2.7 37.9 1.0 O A:VAL288 2.7 33.4 1.0 O B:VAL288 2.7 33.4 1.0 O C:THR287 2.8 37.9 1.0 K B:K1217 3.2 30.0 1.0 C D:VAL288 3.5 13.0 1.0 K A:K1217 3.5 30.0 1.0 C C:VAL288 3.5 13.0 1.0 C A:VAL288 3.5 13.0 1.0 C B:VAL288 3.5 13.0 1.0 C A:THR287 3.7 15.0 1.0 C B:THR287 3.7 15.0 1.0 C D:THR287 3.8 15.0 1.0 C C:THR287 3.9 15.0 1.0 CA D:VAL288 4.0 15.9 1.0 CA A:VAL288 4.0 15.9 1.0 CA C:VAL288 4.0 15.9 1.0 CA B:VAL288 4.0 15.9 1.0 N D:VAL288 4.3 19.4 1.0 N A:VAL288 4.3 19.4 1.0 N B:VAL288 4.4 19.4 1.0 N C:VAL288 4.4 19.4 1.0 N D:GLY289 4.5 13.5 1.0 N B:GLY289 4.5 13.5 1.0 N A:GLY289 4.5 13.5 1.0 N C:GLY289 4.6 13.5 1.0 CA D:GLY289 4.8 12.2 1.0 CA B:GLY289 4.8 12.2 1.0 CA B:THR287 4.8 17.8 1.0 CA A:GLY289 4.9 12.2 1.0 CA A:THR287 4.9 17.8 1.0 CA C:GLY289 4.9 12.2 1.0 CA D:THR287 4.9 17.8 1.0

M.Redhardt, S.Raunser, T.Raisch. Cryo-Em Structure of the SLO1 Potassium Channel with the Auxiliary Gamma 1 Subunit Suggests A Mechanism For Depolarization-Independent Activation. Febs Lett. 2024.
ISSN: ISSN 0014-5793
PubMed: 38553946
DOI: 10.1002/1873-3468.14863