Potassium in PDB 8zaq: EXOC110T Class 2 Channelrhodopsin

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>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 24;

Binding sites:

The binding sites of Potassium atom in the EXOC110T Class 2 Channelrhodopsin (pdb code 8zaq). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 24 binding sites of Potassium where determined in the EXOC110T Class 2 Channelrhodopsin, PDB code: 8zaq:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Potassium binding site 1 out of 24 in the EXOC110T Class 2 Channelrhodopsin


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of EXOC110T Class 2 Channelrhodopsin within 5.0Å range: probe atom residue distance (Å) B Occ A:K301 b:33.3 occ:1.00 CD1 A:TYR81 3.0 16.9 1.0 CE1 A:TYR81 3.0 19.1 1.0 O A:HOH410 3.0 30.0 1.0 CE A:LYS84 3.2 16.4 1.0 O A:CYS77 3.4 16.6 1.0 CB A:MET80 3.6 13.7 1.0 CE A:MET80 3.6 17.1 1.0 SG A:CYS77 3.6 26.3 1.0 OD2 A:ASP105 3.7 22.6 1.0 CG A:TYR81 3.9 17.1 1.0 CD A:LYS84 4.0 13.9 1.0 CZ A:TYR81 4.0 20.8 1.0 N A:TYR81 4.0 12.7 1.0 NZ A:LYS84 4.0 21.1 1.0 OD2 A:ASP229 4.0 28.9 1.0 C A:MET80 4.1 13.8 1.0 C A:CYS77 4.3 13.4 1.0 CA A:CYS77 4.3 12.1 1.0 CA A:MET80 4.4 13.3 1.0 CA A:TYR81 4.5 11.8 1.0 CB A:CYS77 4.5 15.0 1.0 CB A:TYR81 4.6 14.3 1.0 CG A:ASP105 4.6 19.9 1.0 CB A:ASP105 4.6 16.9 1.0 CD2 A:TYR81 4.6 15.0 1.0 CG A:MET80 4.6 13.4 1.0 O A:MET80 4.6 18.4 1.0 OH A:TYR81 4.7 20.6 1.0 CE2 A:TYR81 4.7 18.1 1.0 SD A:MET80 4.7 24.2 1.0

Potassium binding site 2 out of 24 in the EXOC110T Class 2 Channelrhodopsin


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of EXOC110T Class 2 Channelrhodopsin within 5.0Å range: probe atom residue distance (Å) B Occ A:K302 b:28.7 occ:1.00 O A:ASN99 2.7 11.6 1.0 O A:HOH403 2.8 30.0 1.0 O A:HOH401 2.9 30.0 1.0 O A:HOH402 3.2 30.0 1.0 C A:ASN99 3.3 11.6 1.0 CA A:ASN99 3.5 12.4 1.0 CA A:TRP102 3.5 11.1 1.0 O A:TYR101 3.6 14.8 1.0 O A:LEU98 3.6 17.0 1.0 CD2 A:TRP102 3.7 13.3 1.0 CE1 A:TYR222 3.8 9.4 1.0 CE3 A:TRP102 3.9 12.3 1.0 N A:TRP102 3.9 9.9 1.0 CG A:TRP102 3.9 12.7 1.0 C A:TYR101 3.9 11.0 1.0 NZ A:LYS84 4.2 21.1 1.0 CE2 A:TRP102 4.2 12.4 1.0 CB A:TRP102 4.3 11.9 1.0 OH A:TYR222 4.3 12.6 1.0 N A:TYR103 4.4 14.2 1.0 N A:ASN99 4.4 13.1 1.0 C A:LEU98 4.4 13.3 1.0 N A:TRP100 4.4 12.4 1.0 CZ3 A:TRP102 4.4 11.3 1.0 C A:TRP102 4.4 12.6 1.0 OD1 A:ASP105 4.5 19.2 1.0 CD1 A:TRP102 4.5 12.1 1.0 CZ A:TYR222 4.5 11.0 1.0 CB A:ASN99 4.6 11.0 1.0 NE1 A:TRP102 4.6 12.8 1.0 C A:TRP100 4.6 13.1 1.0 O A:TRP100 4.7 12.6 1.0 CD1 A:TYR222 4.7 9.0 1.0 N A:TYR101 4.7 10.9 1.0 CZ2 A:TRP102 4.8 11.1 1.0 CH2 A:TRP102 4.8 11.4 1.0 OD1 A:ASN99 4.9 15.8 1.0 CG A:ASP105 5.0 19.9 1.0

Potassium binding site 3 out of 24 in the EXOC110T Class 2 Channelrhodopsin


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of EXOC110T Class 2 Channelrhodopsin within 5.0Å range: probe atom residue distance (Å) B Occ A:K303 b:38.2 occ:1.00 K A:K304 2.9 42.6 1.0 O A:LYS233 3.2 22.7 1.0 O A:SER70 3.2 23.2 1.0 SG A:CYS74 3.6 21.6 1.0 CA A:GLY237 3.7 21.0 1.0 CD1 A:LEU113 3.8 20.7 1.0 CA A:SER70 3.8 19.0 1.0 C A:SER70 3.9 20.3 1.0 C A:LYS233 4.0 25.7 1.0 N A:GLY237 4.1 22.8 1.0 CG2 A:ILE73 4.1 21.1 1.0 OG A:SER70 4.2 28.0 1.0 CB A:SER70 4.2 21.8 1.0 CB A:ILE73 4.3 17.8 1.0 CA A:LYS233 4.3 26.7 1.0 N A:CYS74 4.4 14.8 1.0 CB A:CYS74 4.6 16.5 1.0 SD A:MET43 4.7 16.5 1.0 CB A:LYS233 4.8 25.5 1.0 CA A:CYS74 4.8 14.7 1.0 CG A:LEU113 4.9 20.5 1.0 C A:ILE73 4.9 15.3 1.0

Potassium binding site 4 out of 24 in the EXOC110T Class 2 Channelrhodopsin


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of EXOC110T Class 2 Channelrhodopsin within 5.0Å range: probe atom residue distance (Å) B Occ A:K304 b:42.6 occ:1.00 OG A:SER70 2.8 28.0 1.0 K A:K303 2.9 38.2 1.0 OD2 A:ASP116 3.0 28.0 1.0 CD2 A:PHE236 3.5 21.2 1.0 CA A:GLY237 3.5 21.0 1.0 CE2 A:PHE236 3.6 20.6 1.0 CB A:SER70 3.8 21.8 1.0 CD1 A:LEU113 4.0 20.7 1.0 N A:GLY237 4.0 22.8 1.0 CA A:SER70 4.0 19.0 1.0 CG A:ASP116 4.0 25.6 1.0 CG A:MET240 4.1 23.9 1.0 CB A:MET240 4.3 23.6 1.0 CG A:LEU113 4.3 20.5 1.0 O A:PHE236 4.4 24.7 1.0 C A:PHE236 4.4 21.1 1.0 CB A:ASP116 4.6 17.7 1.0 CG A:PHE236 4.7 22.1 1.0 C A:GLY237 4.7 19.2 1.0 O A:LYS233 4.8 22.7 1.0 CZ A:PHE236 4.9 20.3 1.0 O A:GLY237 4.9 19.5 1.0 N A:SER70 5.0 19.8 1.0 OD1 A:ASP116 5.0 27.8 1.0 C A:SER70 5.0 20.3 1.0

Potassium binding site 5 out of 24 in the EXOC110T Class 2 Channelrhodopsin


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of EXOC110T Class 2 Channelrhodopsin within 5.0Å range: probe atom residue distance (Å) B Occ A:K305 b:38.3 occ:1.00 O A:HOH409 1.1 30.0 1.0 O A:HOH406 2.0 30.0 1.0 O A:HOH405 2.4 30.0 1.0 OE1 A:GLN218 2.9 18.6 1.0 O A:HOH411 3.0 30.0 1.0 O A:TRP100 3.1 12.6 1.0 CD2 A:TRP100 3.6 10.1 1.0 CE3 A:TRP100 3.7 9.2 1.0 CA A:TRP100 3.7 12.5 1.0 C A:TRP100 3.8 13.1 1.0 CD A:GLN218 3.9 13.8 1.0 OD1 A:ASN18 3.9 18.1 1.0 CG A:TRP100 3.9 8.7 1.0 CE2 A:TRP100 4.0 10.5 1.0 CZ3 A:TRP100 4.1 9.8 1.0 OH A:TYR222 4.1 12.6 1.0 NE2 A:GLN218 4.2 15.6 1.0 CZ2 A:TRP100 4.4 9.9 1.0 CB A:TRP100 4.4 9.7 1.0 CD1 A:TRP100 4.4 8.7 1.0 CH2 A:TRP100 4.4 10.0 1.0 NE1 A:TRP100 4.5 11.2 1.0 O A:ASN99 4.5 11.6 1.0 NE1 A:TRP102 4.6 12.8 1.0 CD1 A:TRP102 4.6 12.1 1.0 CD1 A:ILE17 4.7 18.2 1.0 N A:TRP100 4.8 12.4 1.0

Potassium binding site 6 out of 24 in the EXOC110T Class 2 Channelrhodopsin


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 6 of EXOC110T Class 2 Channelrhodopsin within 5.0Å range: probe atom residue distance (Å) B Occ A:K306 b:30.4 occ:1.00 O A:SER97 2.6 17.7 1.0 O A:HOH401 3.1 30.0 1.0 N A:TYR101 3.2 10.9 1.0 O A:TYR101 3.5 14.8 1.0 CA A:LEU98 3.5 11.5 1.0 CB A:TYR101 3.5 7.7 1.0 C A:LEU98 3.6 13.3 1.0 C A:SER97 3.7 15.0 1.0 CD2 A:TYR101 3.7 9.7 1.0 CA A:TYR101 3.7 9.0 1.0 CD2 A:LEU104 3.8 11.9 1.0 N A:TRP100 3.8 12.4 1.0 O A:LEU98 3.9 17.0 1.0 N A:ASN99 4.0 13.1 1.0 C A:TYR101 4.0 11.0 1.0 N A:LEU98 4.0 13.2 1.0 CG A:TYR101 4.1 8.9 1.0 C A:TRP100 4.2 13.1 1.0 CB A:LEU104 4.2 11.9 1.0 CA A:TRP100 4.3 12.5 1.0 C A:ASN99 4.4 11.6 1.0 CB A:TRP100 4.4 9.7 1.0 CG A:LEU104 4.5 12.3 1.0 CD2 A:LEU98 4.5 14.3 1.0 CA A:ASN99 4.7 12.4 1.0 CB A:LEU98 4.8 14.3 1.0 CE2 A:TYR101 4.8 10.2 1.0 CA A:SER97 5.0 11.2 1.0

Potassium binding site 7 out of 24 in the EXOC110T Class 2 Channelrhodopsin


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 7 of EXOC110T Class 2 Channelrhodopsin within 5.0Å range: probe atom residue distance (Å) B Occ A:K307 b:48.8 occ:1.00 O A:HOH408 2.2 30.0 1.0 OD1 A:ASN67 3.2 27.1 1.0 OG1 A:THR120 3.7 21.7 1.0 NE A:ARG244 3.7 31.2 1.0 CG A:ASN67 3.8 23.2 1.0 CA A:ASN67 3.9 23.3 1.0 C A:PHE119 3.9 19.2 1.0 CB A:PHE119 3.9 16.4 1.0 N A:THR120 3.9 19.1 1.0 O A:VAL66 3.9 24.8 1.0 O A:PHE119 3.9 23.9 1.0 CA A:THR120 4.0 19.9 1.0 N A:ASN67 4.1 21.6 1.0 CD A:ARG244 4.1 31.3 1.0 C A:VAL66 4.1 21.3 1.0 CB A:THR120 4.4 20.0 1.0 ND2 A:ASN67 4.4 24.7 1.0 CB A:ASN67 4.4 23.6 1.0 CG2 A:VAL66 4.4 21.3 1.0 OD1 A:ASP116 4.5 27.8 1.0 CZ A:ARG244 4.5 30.8 1.0 CA A:PHE119 4.5 15.7 1.0 O A:ASP116 4.6 18.8 1.0 CB A:VAL66 4.7 17.3 1.0 CG2 A:THR120 4.8 20.2 1.0 NH2 A:ARG244 4.8 28.0 1.0

Potassium binding site 8 out of 24 in the EXOC110T Class 2 Channelrhodopsin


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 8 of EXOC110T Class 2 Channelrhodopsin within 5.0Å range: probe atom residue distance (Å) B Occ A:K308 b:33.5 occ:1.00 O A:ASN67 2.9 22.5 1.0 N A:GLY71 3.0 17.7 1.0 O A:HOH404 3.1 30.0 1.0 CB A:SER70 3.6 21.8 1.0 CB A:MET43 3.8 14.0 1.0 CA A:GLY71 3.8 15.2 1.0 CA A:SER68 3.8 18.5 1.0 CD2 A:LEU44 3.8 15.9 1.0 C A:SER68 3.9 19.6 1.0 N A:SER70 3.9 19.8 1.0 C A:SER70 3.9 20.3 1.0 O A:SER68 4.0 19.4 1.0 CA A:SER70 4.0 19.0 1.0 C A:ASN67 4.0 19.6 1.0 O A:MET43 4.0 20.4 1.0 C A:MET43 4.1 16.6 1.0 NH1 A:ARG244 4.2 31.2 1.0 CD2 A:LEU47 4.3 20.2 1.0 N A:SER68 4.4 18.0 1.0 N A:LEU44 4.4 16.2 1.0 N A:LEU69 4.5 20.9 1.0 CA A:MET43 4.5 13.3 1.0 CG A:MET43 4.5 15.2 1.0 OG1 A:THR241 4.7 21.2 1.0 CB A:LEU47 4.7 20.9 1.0 CA A:LEU44 4.7 16.2 1.0 OG A:SER70 4.8 28.0 1.0 NH2 A:ARG244 4.8 28.0 1.0 C A:LEU69 4.8 19.0 1.0 SD A:MET43 4.9 16.5 1.0 CG A:LEU44 4.9 14.8 1.0 CZ A:ARG244 4.9 30.8 1.0 C A:GLY71 5.0 15.8 1.0

Potassium binding site 9 out of 24 in the EXOC110T Class 2 Channelrhodopsin


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 9 of EXOC110T Class 2 Channelrhodopsin within 5.0Å range: probe atom residue distance (Å) B Occ B:K301 b:34.4 occ:1.00 CD1 B:TYR81 3.0 17.1 1.0 O B:HOH410 3.0 30.0 1.0 CE1 B:TYR81 3.0 19.5 1.0 CE B:LYS84 3.2 16.2 1.0 O B:CYS77 3.4 15.5 1.0 CE B:MET80 3.5 17.5 1.0 CB B:MET80 3.6 14.3 1.0 SG B:CYS77 3.6 24.1 1.0 OD2 B:ASP105 3.7 21.7 1.0 CG B:TYR81 3.9 16.4 1.0 CD B:LYS84 4.0 13.4 1.0 CZ B:TYR81 4.0 20.9 1.0 N B:TYR81 4.0 11.9 1.0 NZ B:LYS84 4.0 20.5 1.0 OD2 B:ASP229 4.0 27.2 1.0 C B:MET80 4.1 13.3 1.0 C B:CYS77 4.3 14.2 1.0 CA B:CYS77 4.3 13.7 1.0 CA B:MET80 4.4 13.4 1.0 CA B:TYR81 4.5 11.4 1.0 CB B:CYS77 4.5 15.4 1.0 CB B:TYR81 4.6 13.8 1.0 CG B:ASP105 4.6 20.4 1.0 CB B:ASP105 4.6 17.4 1.0 CG B:MET80 4.6 15.3 1.0 CD2 B:TYR81 4.6 15.6 1.0 O B:MET80 4.6 18.1 1.0 OH B:TYR81 4.7 21.0 1.0 CE2 B:TYR81 4.7 17.6 1.0 SD B:MET80 4.7 26.5 1.0

Potassium binding site 10 out of 24 in the EXOC110T Class 2 Channelrhodopsin


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 10 of EXOC110T Class 2 Channelrhodopsin within 5.0Å range: probe atom residue distance (Å) B Occ B:K302 b:29.6 occ:1.00 O B:ASN99 2.7 12.8 1.0 O B:HOH403 2.8 30.0 1.0 O B:HOH401 2.9 30.0 1.0 O B:HOH402 3.2 30.0 1.0 C B:ASN99 3.3 12.5 1.0 CA B:ASN99 3.5 12.8 1.0 CA B:TRP102 3.5 11.4 1.0 O B:TYR101 3.6 17.2 1.0 O B:LEU98 3.6 16.1 1.0 CD2 B:TRP102 3.7 13.3 1.0 CE1 B:TYR222 3.8 10.6 1.0 CE3 B:TRP102 3.9 11.8 1.0 N B:TRP102 3.9 9.8 1.0 CG B:TRP102 3.9 12.9 1.0 C B:TYR101 3.9 11.9 1.0 NZ B:LYS84 4.2 20.5 1.0 CE2 B:TRP102 4.2 11.8 1.0 CB B:TRP102 4.3 11.7 1.0 OH B:TYR222 4.3 13.9 1.0 N B:TYR103 4.4 13.8 1.0 N B:ASN99 4.4 14.1 1.0 C B:LEU98 4.4 13.7 1.0 N B:TRP100 4.4 12.9 1.0 C B:TRP102 4.4 12.7 1.0 CZ3 B:TRP102 4.4 10.5 1.0 CD1 B:TRP102 4.4 12.0 1.0 OD1 B:ASP105 4.5 21.8 1.0 CZ B:TYR222 4.6 11.9 1.0 CB B:ASN99 4.6 11.6 1.0 NE1 B:TRP102 4.6 12.5 1.0 C B:TRP100 4.6 13.8 1.0 O B:TRP100 4.7 13.9 1.0 CD1 B:TYR222 4.7 9.5 1.0 N B:TYR101 4.8 12.8 1.0 CZ2 B:TRP102 4.8 10.2 1.0 CH2 B:TRP102 4.9 10.9 1.0 OD1 B:ASN99 4.9 16.4 1.0 CG B:ASP105 5.0 20.4 1.0

Y.Shan, L.Zhao, M.Chen, X.Li, M.Zhang, D.Pei. Channelrhodopsins with Distinct Chromophores and Binding Patterns. Nat Commun V. 15 7292 2024.
ISSN: ESSN 2041-1723
PubMed: 39181878
DOI: 10.1073/PNAS.1818707116