Potassium in PDB 8vz7: Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan
Enzymatic activity of Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan
All present enzymatic activity of Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan:
1.14.14.1; 1.14.14.51; 1.14.14.52; 1.14.14.53;
1.14.14.1; 1.14.14.51; 1.14.14.52; 1.14.14.53;
Protein crystallography data
The structure of Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan, PDB code: 8vz7
was solved by
M.B.Shah,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 50.01 / 2.53 |
| Space group | I 2 2 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 74.89, 142.17, 163.07, 90, 90, 90 |
| R / Rfree (%) | 15.1 / 21.5 |
Other elements in 8vz7:
The structure of Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan also contains other interesting chemical elements:
| Iron | (Fe) | 1 atom |
| Chlorine | (Cl) | 2 atoms |
Potassium Binding Sites:
The binding sites of Potassium atom in the Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan
(pdb code 8vz7). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan, PDB code: 8vz7:
In total only one binding site of Potassium was determined in the Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan, PDB code: 8vz7:
Potassium binding site 1 out of 1 in 8vz7
Go back to
Potassium Binding Sites List in 8vz7
Potassium binding site 1 out
of 1 in the Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 1 of Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan within 5.0Å range:
|
Reference:
S.J.Parikh,
S.Edara,
S.Deodhar,
A.K.Singh,
K.Maekawa,
Q.Zhang,
K.C.Glass,
M.B.Shah.
Structural and Biophysical Analysis of Cytochrome P450 2C9*14 and *27 Variants in Complex with Losartan J.Inorg.Biochem. 2024.
ISSN: ISSN 0162-0134
DOI: 10.1016/J.JINORGBIO.2024.112622
Page generated: Tue Aug 13 01:12:57 2024
ISSN: ISSN 0162-0134
DOI: 10.1016/J.JINORGBIO.2024.112622
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