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Potassium in PDB 8bzl: Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42
Enzymatic activity of Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42
All present enzymatic activity of Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42:
3.4.25.1;
3.4.25.1;
Protein crystallography data
The structure of Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42, PDB code: 8bzl
was solved by
F.Henneberg,
A.Chari,
E.Jankowska,
J.Witkowska,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 107.12 / 2.14 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 113.915, 203.262, 316.421, 90, 90, 90 |
| R / Rfree (%) | 19.6 / 22.6 |
Other elements in 8bzl:
The structure of Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42 also contains other interesting chemical elements:
| Magnesium | (Mg) | 10 atoms |
| Chlorine | (Cl) | 54 atoms |
Potassium Binding Sites:
The binding sites of Potassium atom in the Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42
(pdb code 8bzl). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 6 binding sites of Potassium where determined in the Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42, PDB code: 8bzl:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6;
In total 6 binding sites of Potassium where determined in the Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42, PDB code: 8bzl:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6;
Potassium binding site 1 out of 6 in 8bzl
Go back to
Potassium Binding Sites List in 8bzl
Potassium binding site 1 out
of 6 in the Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 1 of Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42 within 5.0Å range:
|
Potassium binding site 2 out of 6 in 8bzl
Go back to
Potassium Binding Sites List in 8bzl
Potassium binding site 2 out
of 6 in the Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 2 of Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42 within 5.0Å range:
|
Potassium binding site 3 out of 6 in 8bzl
Go back to
Potassium Binding Sites List in 8bzl
Potassium binding site 3 out
of 6 in the Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 3 of Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42 within 5.0Å range:
|
Potassium binding site 4 out of 6 in 8bzl
Go back to
Potassium Binding Sites List in 8bzl
Potassium binding site 4 out
of 6 in the Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 4 of Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42 within 5.0Å range:
|
Potassium binding site 5 out of 6 in 8bzl
Go back to
Potassium Binding Sites List in 8bzl
Potassium binding site 5 out
of 6 in the Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 5 of Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42 within 5.0Å range:
|
Potassium binding site 6 out of 6 in 8bzl
Go back to
Potassium Binding Sites List in 8bzl
Potassium binding site 6 out
of 6 in the Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 6 of Human 20S Proteasome in Complex with Peptide Activator Peptide BLM42 within 5.0Å range:
|
Reference:
M.Gizynska,
P.Karpowicz,
D.Sowik,
K.Trepczyk,
J.Witkowska,
F.Hennenberg,
A.Chari,
A.Gieldon,
K.Pierzynowska,
L.Gaffke,
G.Wegrzyn,
E.Jankowska.
Peptidic, BLM10-Based Activators of Human 20S Proteasome in Vitro and in Cellulo Enhance Degradation of Proteins Connected with Neurodegeneration. To Be Published.
Page generated: Mon Aug 12 22:09:19 2024
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